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Autor:
Thomas L. Archer
Publikováno v:
Reproduction. 161:V15-V17
Dysfunctional labor is a common cause of cesarean delivery and may be caused by myometrial hypoxia. Obstruction of uterine venous return due to compression of the inferior vena cava by the gravid uterus or the abdominal wall may be an auxiliary cause
Publikováno v:
Reproduction. 156:207-218
Preterm birth continues to be the leading cause of neonatal mortality and morbidities that can extend into adult life. Few treatment options stem from our incomplete understanding of the mechanisms of human labour and delivery. Activation of the infl
Autor:
James Davis, Pai-Jong Stacy Tsai, Sandra Y. Yamamoto, Kelly Yamasato, Gillian D. Bryant-Greenwood
Publikováno v:
Reproduction. 154:67-77
Relaxin, a systemic and placental hormone, has potential roles in fetoplacental growth. Human placenta expresses two RLN genes, RLNH1 and RLNH2. Maternal obesity is common and is associated with abnormal fetal growth. Our aims were to relate systemic
Publikováno v:
Reproduction.
The type of stimuli triggering GnRH secretion has been used to classify mammalian species into two categories: spontaneous or induced ovulators. In the former, ovarian steroids produced by a mature follicle elicit the release of GnRH from the hypotha
Autor:
Matthew S. Payne, Lisa F Stinson, Sarah J. Stock, Demelza J. Ireland, John P. Newnham, Jeffrey A. Keelan, Matthew W. Kemp
Publikováno v:
REPRODUCTION. 147:313-320
Intrauterine infection and inflammation are responsible for the majority of early (N-acetyl cysteine (NAC), SB239063, TPCA-1 and NEMO binding domain inhibitor (NBDI)) were assessed on human and ovine gestational membrane inflammation. Full-thickness
Autor:
Francisco Gaytan, Raúl Gómez, Hortensia Ferrero, Carlos Simón, Francisco Delgado-Rosas, Juan A. Garcia-Velasco, Antonio Pellicer
Publikováno v:
REPRODUCTION. 142:745-755
Implantation of a retrogradely shed endometrium during menstruation requires an adequate blood supply, which allows the growth of endometriotic lesions. This suggests that the development of endometriosis can be impaired by inhibiting angiogenesis. T
Autor:
Michael Clay, Hamish M. Fraser, W. Colin Duncan, Helen Wilson, Emily C Turner, Tiina Kipari, Katie J. Mylonas, Jeremy Hughes
Publikováno v:
Reproduction (Cambridge, England)
Turner, E C, Hughes, J, Wilson, H, Clay, M, Mylonas, K J, Kipari, T, Duncan, W C & Fraser, H M 2011, ' Conditional ablation of macrophages disrupts ovarian vasculature ', Reproduction, vol. 141, no. 6, pp. 821-831 . https://doi.org/10.1530/REP-10-0327
Turner, E C, Hughes, J, Wilson, H, Clay, M, Mylonas, K J, Kipari, T, Duncan, W C & Fraser, H M 2011, ' Conditional ablation of macrophages disrupts ovarian vasculature ', Reproduction, vol. 141, no. 6, pp. 821-831 . https://doi.org/10.1530/REP-10-0327
Macrophages are the most abundant immune cell within the ovary. Their dynamic distribution throughout the ovarian cycle and heterogenic array of functions suggest the involvement in various ovarian processes, but their functional role has yet to be f
Autor:
Patrick M. Catalano
Publikováno v:
REPRODUCTION. 140:365-371
There has been a significant increase over the past few decades in the number of reproductive age women who are either overweight or obese. Overweight and obese women are at increased risk for having decreased insulin sensitivity as compared with lea
Autor:
A.H. Balen, Christopher Brewer
Publikováno v:
REPRODUCTION. 140:347-364
Whilst many multiparous women are obese (body mass index >30 kg/m2), obesity has been associated with impaired fecundity; however, the mechanism which links obesity to reduced fertility remains to be fully elucidated. Obese women, particularly those
Autor:
Mary Lynn Johnson, Dale A. Redmer, Anna T. Grazul-Bilska, Lawrence P. Reynolds, Pawel P. Borowicz, Jerzy J. Bilski, Megan Minten, Robert Wroblewski
Publikováno v:
REPRODUCTION. 140:165-174
Placental vascular development (angiogenesis) is critical for placental function and thus for normal embryonic/fetal growth and development. Specific environmental factors or use of assisted reproductive techniques may result in poor placental angiog