Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Zhengyi Wang"'
Publikováno v:
Regular and Young Investigator Award Abstracts.
Publikováno v:
Regular and Young Investigator Award Abstracts.
Autor:
Wei Cao, Chan Chen, Joan Huaqiong Shen, Julia Neugebauer, Christian Augsberger, Jane Meng, Stefan Haertle, Zhengyi Wang
Publikováno v:
Regular and young investigator award abstracts.
Background Extensive investigations into the tumor microenvironment (TME) have uncovered molecular mechanisms linking aberrant complement activation and cancer progression. Specifically, C5a, as a highly potent chemoattractant, recruits immune suppre
Autor:
Jordan Berlin, Wael Harb, Alex Adjei, Yan Xing, Paul Swiecicki, Mahesh Seetharam, Lakshminarayanan Nandagopal, Ajay Gopal, Cong Xu, Yuan Meng, Linda Lee, Yonggang Zhao, Zhengyi Wang, Joan Huaqiong Shen
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Background CD47 blockade using SIRPα-Fc or anti-CD47 antibodies results in inhibition of the ‘do not eat’ signal and activation of phagocytosis and has emerged as a promising cancer treatment strategy. However, targeting CD47 leads to various he