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Autor:
Akira Kurisaki, Yuko Yamanaka, Hisashi Hirano, Hiroyuki Fukuda, Makoto Asashima, Hiromu Sugino, Atsushi Intoh
Publikováno v:
PROTEOMICS. 9:126-137
Embryonic stem cells (ESCs) are established from the inner cell mass of preimplantation embryos, are capable of self-renewal, and exhibit pluripotency. Given these unique properties, ESCs are expected to have therapeutic potential in regenerative med
Autor:
Kohji Nagano, Takashi Shinkawa, Nobuhiro Takahashi, Kazuto Nunomura, Masato Taoka, Chiharu Itagaki, Yoshio Yamauchi, Nobuko Okamura, Tomonori Izumi, Toshiaki Isobe
Publikováno v:
PROTEOMICS. 5:1346-1361
A protein subset expressed in the mouse embryonic stem (ES) cell line, E14-1, was characterized by mass spectrometry-based protein identification technology and data analysis. In total, 1790 proteins including 365 potential nuclear and 260 membrane p
Publikováno v:
PROTEOMICS. 17:1600294
EVA1A is an autophagy-related protein, which plays an important role in embryonic neurogenesis. In this study, we found that loss of EVA1A could decrease neural differentiation in the brain of adult Eva1a-/- mice. To determine the mechanism underlyin
Autor:
Brian A. Gerwe, Franklin D. West, Ron Orlando, Peggi M. Angel, Steven L. Stice, Amber Young, Kowser Hasneen
Publikováno v:
Proteomics. 11(12)
Cultured human embryonic stem cells (hESCs) and derived derivatives contain heterogeneous cell populations with varying degrees of differentiation and karyotypic stability. The inability to isolate homogenous population presents a challenge toward ce