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Autor:
Niina Lietzén, Sandra Söderholm, Tiina Öhman, Sampsa Matikainen, Tuula A. Nyman, Maruthibabu Paidikondala
Publikováno v:
PROTEOMICS. 15:2087-2097
Sendai virus (SeV) is a common respiratory pathogen in mice, rats, and hamsters. Host cell recognition of SeV is mediated by pathogen recognition receptors, which recognize viral components and induce intracellular signal transduction pathways that a
Publikováno v:
Proteomics
Rice yield and quality are adversely affected by increasing global surface temperature, and are strongly attributed to high night temperature (HNT) than high daytime temperature. However, the molecular mechanism underlying the heat-tolerant character
Autor:
Bárbara Du-Rocher, Luciana Pizzatti, Julliana Ferreira Sant’Anna, Milene Rangel da Costa, Eliana Abdelhay, Adalberto Vieyra, Rafael Soares Lindoso
Publikováno v:
PROTEOMICS. 14:1480-1493
Acute kidney injury (AKI) is one of the more frequent and lethal pathological conditions seen in intensive care units. Currently available treatments are not totally effective but stem cell-based therapies are emerging as promising alternatives, espe
Publikováno v:
Proteomics
Tropomyosin-related kinase A (TrkA) is a receptor-type protein tyrosine kinase and exploits pleiotypic roles via nerve growth factor (NGF)-dependent or NGF-independent mechanisms in various cell types. Here, we showed that the inhibition of TrkA acti
Autor:
Patrick Lécine, Subhash Thalappilly, Philippe Soubeyran, Odile Gayet, Muhtadi Suliman, Juan L. Iovanna, Aurélie Hermant, Nelson Dusetti
Publikováno v:
PROTEOMICS. 8:3071-3081
Pancreatic ductal adenocarcinoma (PDAC) is a fatal disease that shows minimal response to chemotherapy. Genetic changes involved in the progression of PDAC concern genes that encode proteins related to signal transduction networks. This fact reveals
Autor:
Qingsong Lin, Ping Chen, Canhua Huang, Quek Choon Lau, Jiong Li, Aiping Tong, Lijuan Chen, Yuquan Wei, Xia Zhao, Lihong Wu, Hong Tang
Publikováno v:
PROTEOMICS. 8:2012-2023
Hepatitis B virus (HBV) is one of the major etiological factors responsible for acute and chronic liver disease and for the development of hepatocellular carcinoma (HCC). To determine the effects of HBV replication on host cell-protein expression, we
Autor:
Lili Li, Wei Luo, Min Tang, Guangrong Yan, Yongguang Tao, Yong Wu, Zigang Dong, Ya Cao, Yi-ping Liu, Sufang Liu
Publikováno v:
PROTEOMICS. 6:1810-1821
Previous studies have shown that the Epstein-Barr virus-encoded latent membrane protein1 (LMP1) could activate nuclear factor kappa B, activator protein-1, and Janus kinases/signal transducer and activation of transcription factors pathways. However,
Publikováno v:
Proteomics. 15(13)
Lactobacillus acidophilus probiotic bacteria have lasting beneficial health effects in the gastrointestinal tract, including protecting against pathogens, improving immunomodulation, and producing beneficial bacteria-derived molecules. In lipopolysac
Autor:
Oda Stoevesandt, Karsten Köhler, Roland Brock, Martin Elbs, Rainer Fischer, Thomas André, Annemarie C. Lellouch
Publikováno v:
Proteomics
Proteomics, 2005, 5 (8), pp.2010-7. ⟨10.1002/pmic.200401095⟩
Proteomics, Wiley-VCH Verlag, 2005, 5 (8), pp.2010-7. ⟨10.1002/pmic.200401095⟩
Proteomics, 2005, 5 (8), pp.2010-7. ⟨10.1002/pmic.200401095⟩
Proteomics, Wiley-VCH Verlag, 2005, 5 (8), pp.2010-7. ⟨10.1002/pmic.200401095⟩
The formation of protein complexes is a hallmark of cellular signal transduction. Here, we show that peptide microarrays provide a robust and quantitative means to detect signalling-dependent changes of molecular interactions. Recruitment of a protei
Autor:
James D. Pomonis, Gregory F. Egnaczyk, John E. Maggio, Joseph R. Ghilardi, Julie A Schmidt, Patrick W. Mantyh, Christopher M. Peters, Scott D. Rogers
Publikováno v:
PROTEOMICS. 3:689-698
Reactive gliosis is an invariant feature of the pathology of central nervous system (CNS) injury and a major determinant of neuronal survival and regeneration. To begin to understand the alterations in astrocyte protein expression that drive glial ch