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Autor:
Zhi-Ping Zhang, Kaio Kitazato, Qing-Yu He, Feng Ge, Wang Yifei, Sheng Xiong, Ge Liu, Guo Chaowan, Xian-En Zhang
Publikováno v:
PROTEOMICS. 10:2337-2347
MIP-T3 (microtubule-interacting protein associated with TRAF3) is a microtubule-interacting protein that evolutionarily conserved from worms to humans, but whose cellular functions remains unknown. To get insight into the functions of MIP-T3, we set
Publikováno v:
PROTEOMICS. 9:4071-4086
The RAD51 family of proteins is involved in homologous recombination (HR) DNA repair and maintaining chromosome integrity. To identify candidates that interact with HR proteins, the mouse RAD51C, RAD51D and XRCC2 proteins were purified using bacteria
Autor:
Patrick Lécine, Subhash Thalappilly, Philippe Soubeyran, Odile Gayet, Muhtadi Suliman, Juan L. Iovanna, Aurélie Hermant, Nelson Dusetti
Publikováno v:
PROTEOMICS. 8:3071-3081
Pancreatic ductal adenocarcinoma (PDAC) is a fatal disease that shows minimal response to chemotherapy. Genetic changes involved in the progression of PDAC concern genes that encode proteins related to signal transduction networks. This fact reveals
Autor:
Stacy L. DeBlasio, Michelle Cilia, Michael J. MacCoss, Richard J. Johnson, Alexander V. Karasev, Stewart M. Gray, Michelle Sweeney
Publikováno v:
Proteomics. 15(12)
Potato leafroll virus (PLRV) produces a readthrough protein (RTP) via translational readthrough of the coat protein amber stop codon. The RTP functions as a structural component of the virion and as a nonincorporated protein in concert with numerous
Autor:
Lianghao Lu, Tomohiko Fukuda, Tomoya Isaji, Jianguo Gu, Ryota Akama, Masayuki Ozawa, Yuya Sato, Naoyuki Taniguchi, Yoshinobu Kariya
Publikováno v:
Proteomics. 8(16)
Recently, our research group investigated the effects of cell-cell interactions on N-linked oligosaccharides (N-glycans). We found that N-acetylglucosaminyltransferase III (GnT-III) activity, and thus, the enzyme product-bisected N-glycans were induc
Autor:
E Olmedo, Núria Canela, Elielson Souza-Rodrígues, Neus Agell, Erica Friedrich-Heineken, Jorge Vera, Sonia Brun, Montserrat Jaumot, Ulrich Hübscher, Oriol Bachs, Josep Maria Estanyol
Publikováno v:
Proteomics. 7(22)
The p16(ink4a) tumor suppressor protein plays a critical role in cell cycle control, tumorogenesis and senescence. The best known activity for p16(ink4a) is the inhibition of the activity of CDK4 and CDK6 kinases, both playing a key role in cell cycl
Autor:
Alberto Bavelloni, Irene Faenza, Lucio Cocco, Daniela Parisi, Manuela Piazzi, Nadir M. Maraldi, Ivan Matic, Gabriella Cioffi
Publikováno v:
Proteomics
An extensive body of evidence links inositide-specific phospholipase C (PLC) to the nucleus and the main isoform located in the nucleus is PLCbeta(1). Constitutive overexpression of nuclear PLCbeta(1) has been previously shown to inhibit Friend eryth