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Publikováno v:
Proteomics, 20(12). Wiley-VCH Verlag
Quantitative proteomic studies are contributing greatly to the understanding of the spermatozoon through the provision of detailed information on the proteins spermatozoa acquire and shed in the acquisition of fertility. Extracellular vesicles (EVs)
Publikováno v:
Proteomics. 20(7)
Transgelin is a protein reported to be a marker of several cancers. However, previous studies have shown both up- and down-regulation of transgelin in tumors when compared with non-tumor tissues and the mechanisms whereby transgelin may affect the de
Publikováno v:
Proteomics. 19(19)
Females have less incidence/prevalence of kidney stone disease than males. Estrogen thus may serve as the protective factor but with unclear mechanism. This study explores cellular mechanism underlying such stone preventive mechanism of estrogen. Mad
Autor:
George Hajishengallis, Abe Toshiharu, Jonas Grossmann, Kai Bao, Tetsuhiro Kajikawa, Xiaofei Li, Nagihan Bostanci, Nathalie Selevsek
Publikováno v:
Proteomics
Understanding the progression of periodontal tissue destruction is at the forefront of periodontal research. The authors aimed to capture the dynamics of gingival tissue proteome during the initiation and progression of experimental (ligature-induced
Publikováno v:
PROTEOMICS. 20:1900294
Schwann cells (SC) are essential for the growth, maintenance, and regeneration of peripheral nerves, but the proteome of normal human SC is poorly defined. Here, a proteomic analysis by LC-MS/MS is performed to define the protein expression profile o
Publikováno v:
PROTEOMICS. 19:1800432
Niemann-Pick disease, type C1 (NPC1) is a fatal, autosomal recessive, neurodegenerative disorder caused by mutations in the NPC1 gene. As a result, there is accumulation of unesterified cholesterol and sphingolipids in the late endosomal/lysosomal sy
Autor:
Shu Wen Wen, Andreas Möller, Emma L. Norris, Richard J. Lobb, Sophie Krumeich, Marcus L. Hastie, Luize G. Lima
Publikováno v:
PROTEOMICS. 19:1800180
A manner in which cells can communicate with each other is via secreted nanoparticles termed exosomes. These vesicles contain lipids, nucleic acids, and proteins, and are said to reflect the cell-of-origin. However, for the exosomal protein content,
Autor:
Julia Calzada-Wack, Soile Tapio, Michael J. Atkinson, Zarko Barjaktarovic, Hakan Sarioglu, Andreas Vogt, Frauke Neff, Omid Azimzadeh, Marcus Conrad, Harry Scherthan, Christian Buske, Michaela Aubele
Publikováno v:
Practical proteomics 11(16), 3299-3311 (2011). doi:10.1002/pmic.201100178
Accidental nuclear scenarios lead to environmental contamination of unknown level. Immediate radiation-induced biological responses that trigger processes leading to adverse health effects decades later are not well understood. A comprehensive proteo
Autor:
Angela Bamundo, Giovanni Nassa, Roberta Tarallo, E. Nola, Ornella Paris, Marc Baumann, Tuula A. Nyman, Angelo Facchiano, Alessandro Weisz, Concetta Ambrosino
Publikováno v:
Proteomics. 11(1)
Estrogen receptor α (ER-α) is a key mediator of estrogen actions in breast cancer (BC) cells. Understanding the effects of ligand-activated ER-α in target cells requires identification of the molecular partners acting in concert with this nuclear