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Autor:
Gustavo B. Menezes, Rodrigo A. Fraga-Silva, Letícia A.S. Pereira, Liliane Diniz de Araújo, Anderson J. Ferreira, Heder José Ribeiro, Vinayak Shenoy, Marilda L. A De Maria, Mohan K. Raizada
Publikováno v:
Protein & Peptide Letters. 23:9-16
Previous studies have shown that activation of endogenous angiotensin-converting enzyme 2 (ACE2) results in various beneficial effects in the cardiovascular system. Recently, a new ACE2 activator, named diminazene aceturate (DIZE), was described. Her
Autor:
Sérgio Henrique Sousa Santos, Alfredo Maurício Batista de Paula, Deborah de Farias Lelis, Antônio Prates Caldeira, João Marcus Oliveira Andrade, Emillio Cesar Neves Ferreira, Thaisa de Almeida Pinheiro, André Luiz Sena Guimarães, John David Feltenberger, Thales de Almeida Pinheiro
Publikováno v:
Protein & Peptide Letters. 24
Background Lipogenesis is a process that involves the fatty acids synthesis. Resveratrol and enalapril have been studied for their beneficial physiological properties on the glucose and lipid metabolism. Objectives The aim of the present study was to
Publikováno v:
Protein & Peptide Letters. 22:736-742
Former data of our workgroup indicated that the accumulation of oxidized amino acids (meta- and ortho-tyrosine) due to oxidative stress may play an important role in the impaired insulininduced vasoactive properties of different arterial segments. Th
Publikováno v:
Protein & Peptide Letters. 22:256-263
Earlier peptidomic analysis of the skin secretion of Xenopus amieti led to the identification of orthologs of magainins and other peptides. This study investigated the degradation, in vitro insulin-releasing and acute metabolic effects of magainin-AM
Publikováno v:
Protein & Peptide Letters. 15:850-853
Advanced glycation end products (AGEs)-their receptor (RAGE) axis plays a central role in the pathogenesis of diabetic microangiopathy. Since the pathophysiological crosstalk between the AGEs-RAGE system and angiotensin II has also been associated wi
Autor:
D.E. Barre
Publikováno v:
Protein & Peptide Letters. 14:839-842
Lipoprotein (a) (Lp (a)) may be pro-thrombotic in humans due to its apolipoprotein (a) (apo(a))-mediated decreases in fibrinolysis. Such decreased fibrinolysis arises putatively from interference with plasminogen conversion to plasmin due to the cons