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Autor:
Weiwei Nie, Chen-Yu Zhang, Xi Chen, Minghui Cao, Dongxia Hou, Ke Zen, Xiaohong Jiang, Xiaoxiang Guan, Xin Yan, Yujing Zhang, Jing Li
Publikováno v:
Protein & Cell
MicroRNAs (miRNAs) are small, non-coding RNAs that function as post-transcriptional regulators of gene expression. The deregulated expression of miRNAs is associated with a variety of diseases, including breast cancer. In the present study, we found
Publikováno v:
Protein & Cell
Our previous studies indicate that phosphatidylinositol 4-kinase IIα can promote the growth of multi-malignant tumors via HER-2/PI3K and MAPK pathways. However, the molecular mechanisms of this pathway and its potential for clinical application rema
Autor:
Zhu Liu, Jie Ran, Jun Zhou, Min Liu, Bing Yan, Youguang Luo, Dengwen Li, Xin Dong, Jie Chen, Ruming Liu
Publikováno v:
Protein & Cell
Paclitaxel is a microtubule-targeting agent widely used for the treatment of many solid tumors. However, patients show variable sensitivity to this drug, and effective diagnostic tests predicting drug sensitivity remain to be investigated. Herein, we