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Autor:
Christian Grandfils, João Pedro Nunes, Tatyana Strekalova, Ana Isabel Santos, Julie Vignisse, Alexei Bolkunov, Harry W.M. Steinbusch, Sergei Olegovich Bachurin
Publikováno v:
Progress in Neuro-Psychopharmacology & Biological Psychiatry, 35(2), 510-522. Elsevier Science
Pre-clinical and clinical studies on dimebon (dimebolin or latrepirdine) have demonstrated its use as a cognitive enhancer. Here, we show that dimebon administered to 3-month-old C57BL6N mice 15 min prior to training in both appetitive and inhibitory
Publikováno v:
Progress in neuro-psychopharmacologybiological psychiatry. 26(7-8)
Background: YKP10A is a novel, new antidepressant that may affect dopamine neurotransmission. We present results from the first Phase II clinical trial of YKP10A antidepressant activity in patients with major depression. Methods: This was a single-si
Autor:
Christoph Fehr, Alexandra Schleicher, I. O. N. Anghelescu, Armin Szegedi, Christoph Klawe, Christoph Hiemke, Norbert Dahmen
Publikováno v:
Progress in neuro-psychopharmacologybiological psychiatry. 25(5)
1. Alterations in the serotonergic neurotransmission have been frequently described for patients suffering from alcoholism, anxiety disorders and narcolepsy. 2. The authors tested for association of the 5-HT2A receptor polymorphism (T102C) and the in