Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Christian Drosten"'
Autor:
Baxolele Mhlekude, Dylan Postmus, Saskia Stenzel, January Weiner, Jenny Jansen, Francisco J Zapatero-Belinchón, Ruth Olmer, Anja Richter, Julian Heinze, Nicolas Heinemann, Barbara Mühlemann, Simon Schroeder, Terry C Jones, Marcel A Müller, Christian Drosten, Andreas Pich, Volker Thiel, Ulrich Martin, Daniela Niemeyer, Gisa Gerold, Dieter Beule, Christine Goffinet
Publikováno v:
PLoS Pathogens, Vol 19, Iss 9, p e1011657 (2023)
Inhibitors of bromodomain and extra-terminal proteins (iBETs), including JQ-1, have been suggested as potential prophylactics against SARS-CoV-2 infection. However, molecular mechanisms underlying JQ-1-mediated antiviral activity and its susceptibili
Externí odkaz:
https://doaj.org/article/68f2a8478fe7484fafc679780534d4ce
Autor:
B. Karina Montero, Wasimuddin, Nina Schwensow, Mark A. F. Gillingham, Yedidya R. Ratovonamana, S. Jacques Rakotondranary, Victor Corman, Christian Drosten, Jörg U. Ganzhorn, Simone Sommer
Publikováno v:
PLoS Pathogens, Vol 17, Iss 11 (2021)
Until recently, the study of major histocompability complex (MHC) mediated immunity has focused on the direct link between MHC diversity and susceptibility to parasite infection. However, MHC genes can also influence host health indirectly through th
Externí odkaz:
https://doaj.org/article/257fc14d68e8438aa6e506af41d08873
Autor:
Simon Käfer, Sofia Paraskevopoulou, Florian Zirkel, Nicolas Wieseke, Alexander Donath, Malte Petersen, Terry C Jones, Shanlin Liu, Xin Zhou, Martin Middendorf, Sandra Junglen, Bernhard Misof, Christian Drosten
Publikováno v:
PLoS Pathogens, Vol 15, Iss 12, p e1008224 (2019)
The spectrum of viruses in insects is important for subjects as diverse as public health, veterinary medicine, food production, and biodiversity conservation. The traditional interest in vector-borne diseases of humans and livestock has drawn the att
Externí odkaz:
https://doaj.org/article/cb24a7a5eeeb457e9205a86420270bca
Autor:
Daniela Niemeyer, Kirstin Mösbauer, Eva M Klein, Andrea Sieberg, Robert C Mettelman, Anna M Mielech, Ronald Dijkman, Susan C Baker, Christian Drosten, Marcel A Müller
Publikováno v:
PLoS Pathogens, Vol 14, Iss 9, p e1007296 (2018)
SARS-coronavirus (CoV) is a zoonotic agent derived from rhinolophid bats, in which a plethora of SARS-related, conspecific viral lineages exist. Whereas the variability of virulence among reservoir-borne viruses is unknown, it is generally assumed th
Externí odkaz:
https://doaj.org/article/e2c3a18d260f4854ab9ea12b5d41be2e
Autor:
Christian Gortazar, Leslie A Reperant, Thijs Kuiken, José de la Fuente, Mariana Boadella, Beatriz Martínez-Lopez, Francisco Ruiz-Fons, Agustin Estrada-Peña, Christian Drosten, Graham Medley, Richard Ostfeld, Townsend Peterson, Kurt C VerCauteren, Christian Menge, Marc Artois, Constance Schultsz, Richard Delahay, Jordi Serra-Cobo, Robert Poulin, Frederic Keck, A Alonso Aguirre, Heikki Henttonen, Andrew P Dobson, Susan Kutz, Juan Lubroth, Atle Mysterud
Publikováno v:
PLoS Pathogens, Vol 10, Iss 6, p e1004129 (2014)
Externí odkaz:
https://doaj.org/article/0811ab6411644ee7a49f6c7eca5c173c
Autor:
Anna Lundin, Ronald Dijkman, Tomas Bergström, Nina Kann, Beata Adamiak, Charles Hannoun, Eveline Kindler, Hulda R Jónsdóttir, Doreen Muth, Joeri Kint, Maria Forlenza, Marcel A Müller, Christian Drosten, Volker Thiel, Edward Trybala
Publikováno v:
PLoS Pathogens, Vol 10, Iss 5, p e1004166 (2014)
Coronaviruses raise serious concerns as emerging zoonotic viruses without specific antiviral drugs available. Here we screened a collection of 16671 diverse compounds for anti-human coronavirus 229E activity and identified an inhibitor, designated K2
Externí odkaz:
https://doaj.org/article/c8481c7f14ad4444af2631693445ff2f
Autor:
Jan Felix Drexler, Victor Max Corman, Marcel Alexander Müller, Alexander N Lukashev, Anatoly Gmyl, Bruno Coutard, Alexander Adam, Daniel Ritz, Lonneke M Leijten, Debby van Riel, Rene Kallies, Stefan M Klose, Florian Gloza-Rausch, Tabea Binger, Augustina Annan, Yaw Adu-Sarkodie, Samuel Oppong, Mathieu Bourgarel, Daniel Rupp, Bernd Hoffmann, Mathias Schlegel, Beate M Kümmerer, Detlev H Krüger, Jonas Schmidt-Chanasit, Alvaro Aguilar Setién, Veronika M Cottontail, Thiravat Hemachudha, Supaporn Wacharapluesadee, Klaus Osterrieder, Ralf Bartenschlager, Sonja Matthee, Martin Beer, Thijs Kuiken, Chantal Reusken, Eric M Leroy, Rainer G Ulrich, Christian Drosten
Publikováno v:
PLoS Pathogens, Vol 9, Iss 6, p e1003438 (2013)
Hepatitis C virus (HCV) is among the most relevant causes of liver cirrhosis and hepatocellular carcinoma. Research is complicated by a lack of accessible small animal models. The systematic investigation of viruses of small mammals could guide effor
Externí odkaz:
https://doaj.org/article/9d69d55584884b4f8a36a3eb0a8044b1
Autor:
Susanne Pfefferle, Julia Schöpf, Manfred Kögl, Caroline C Friedel, Marcel A Müller, Javier Carbajo-Lozoya, Thorsten Stellberger, Ekatarina von Dall'Armi, Petra Herzog, Stefan Kallies, Daniela Niemeyer, Vanessa Ditt, Thomas Kuri, Roland Züst, Ksenia Pumpor, Rolf Hilgenfeld, Frank Schwarz, Ralf Zimmer, Imke Steffen, Friedemann Weber, Volker Thiel, Georg Herrler, Heinz-Jürgen Thiel, Christel Schwegmann-Wessels, Stefan Pöhlmann, Jürgen Haas, Christian Drosten, Albrecht von Brunn
Publikováno v:
PLoS Pathogens, Vol 7, Iss 10, p e1002331 (2011)
Coronaviruses (CoVs) are important human and animal pathogens that induce fatal respiratory, gastrointestinal and neurological disease. The outbreak of the severe acute respiratory syndrome (SARS) in 2002/2003 has demonstrated human vulnerability to
Externí odkaz:
https://doaj.org/article/59ad8fba594d461dbfeef4a5582bf8f4
Autor:
Marcel A. Müller, E. Klein, Daniela Niemeyer, Kirstin Mösbauer, Robert C. Mettelman, Christian Drosten, Anna M. Mielech, Ronald Dijkman, Susan C. Baker, Andrea Sieberg
Publikováno v:
PLoS Pathogens, Vol 14, Iss 9, p e1007296 (2018)
PLoS Pathogens
Niemeyer, Daniela; Mösbauer, Kirstin; Klein, Eva M; Sieberg, Andrea; Mettelman, Robert C; Mielech, Anna M; Dijkman, Ronald; Baker, Susan C; Drosten, Christian; Müller, Marcel A (2018). The papain-like protease determines a virulence trait that varies among members of the SARS-coronavirus species. PLoS pathogens, 14(9), e1007296. Public Library of Science 10.1371/journal.ppat.1007296
PLOS Pathogens
PLoS Pathogens
Niemeyer, Daniela; Mösbauer, Kirstin; Klein, Eva M; Sieberg, Andrea; Mettelman, Robert C; Mielech, Anna M; Dijkman, Ronald; Baker, Susan C; Drosten, Christian; Müller, Marcel A (2018). The papain-like protease determines a virulence trait that varies among members of the SARS-coronavirus species. PLoS pathogens, 14(9), e1007296. Public Library of Science 10.1371/journal.ppat.1007296
PLOS Pathogens
SARS-coronavirus (CoV) is a zoonotic agent derived from rhinolophid bats, in which a plethora of SARS-related, conspecific viral lineages exist. Whereas the variability of virulence among reservoir-borne viruses is unknown, it is generally assumed th
Autor:
Julia Schöpf, Javier Carbajo-Lozoya, Georg Herrler, Stefan Pöhlmann, Marcel A. Müller, Friedemann Weber, Christian Drosten, Heinz Jürgen Thiel, Ralf Zimmer, Petra Herzog, Jürgen Haas, Susanne Pfefferle, Thomas Kuri, Imke Steffen, Volker Thiel, Manfred Kögl, Frank Schwarz, Stefan Kallies, Daniela Niemeyer, Ekatarina von Dall'Armi, Albrecht von Brunn, Caroline C. Friedel, Roland Züst, Christel Schwegmann-Weßels, Thorsten Stellberger, Rolf Hilgenfeld, Vanessa Ditt, Ksenia Pumpor
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 7, Iss 10, p e1002331 (2011)
Pfefferle, S, Schoepf, J, Koegl, M, Friedel, C C, Mueller, M A, Carbajo-Lozoya, J, Stellberger, T, von Dall'Armi, E, Herzog, P, Kallies, S, Niemeyer, D, Ditt, V, Kuri, T, Zuest, R, Pumpor, K, Hilgenfeld, R, Schwarz, F, Zimmer, R, Steffen, I, Weber, F, Thiel, V, Herrler, G, Thiel, H-J, Schwegmann-Wessels, C, Poehlmann, S, Haas, J, Drosten, C & von Brunn, A 2011, ' The SARS-Coronavirus-Host Interactome: Identification of Cyclophilins as Target for Pan-Coronavirus Inhibitors ', PLoS Pathogens, vol. 7, no. 10, e1002331, pp.-. https://doi.org/10.1371/journal.ppat.1002331
PLoS pathogens
PLoS Pathogens, Vol 7, Iss 10, p e1002331 (2011)
Pfefferle, S, Schoepf, J, Koegl, M, Friedel, C C, Mueller, M A, Carbajo-Lozoya, J, Stellberger, T, von Dall'Armi, E, Herzog, P, Kallies, S, Niemeyer, D, Ditt, V, Kuri, T, Zuest, R, Pumpor, K, Hilgenfeld, R, Schwarz, F, Zimmer, R, Steffen, I, Weber, F, Thiel, V, Herrler, G, Thiel, H-J, Schwegmann-Wessels, C, Poehlmann, S, Haas, J, Drosten, C & von Brunn, A 2011, ' The SARS-Coronavirus-Host Interactome: Identification of Cyclophilins as Target for Pan-Coronavirus Inhibitors ', PLoS Pathogens, vol. 7, no. 10, e1002331, pp.-. https://doi.org/10.1371/journal.ppat.1002331
PLoS pathogens
Coronaviruses (CoVs) are important human and animal pathogens that induce fatal respiratory, gastrointestinal and neurological disease. The outbreak of the severe acute respiratory syndrome (SARS) in 2002/2003 has demonstrated human vulnerability to