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Autor:
Chanson J. Brumme, Nozomi Kuse, Zabrina L. Brumme, Tomohiro Akahoshi, Hayato Murakoshi, Takayuki Chikata, Masafumi Takiguchi, Shinichi Oka, Naoki Ishizuka, Madoka Koyanagi, Hiroyuki Gatanaga
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 16, Iss 12, p e1009177 (2020)
PLoS Pathogens, Vol 16, Iss 12, p e1009177 (2020)
HIV-1 strains harboring immune escape mutations can persist in circulation, but the impact of selection by multiple HLA alleles on population HIV-1 dynamics remains unclear. In Japan, HIV-1 Reverse Transcriptase codon 135 (RT135) is under strong immu