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Autor:
Ali Hassan, Nicolas Blanchard
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 18, Iss 2, p e1010212 (2022)
PLoS Pathogens, Vol 18, Iss 2, p e1010212 (2022)
It is well established that by modulating various immune functions, host infection may alter the course of concomitant inflammatory diseases, of both infectious and autoimmune etiologies. Beyond the major impact of commensal microbiota on the immune
Autor:
Eric M. Burton, Benjamin E. Gewurz
Publikováno v:
PLoS Pathogens, Vol 18, Iss 2, p e1010254 (2022)
PLoS Pathogens
PLoS Pathogens
Autor:
Damien Glon, Géraldine Vilmen, Daniel Perdiz, Eva Hernandez, Guillaume Beauclair, Frédérique Quignon, Clarisse Berlioz-Torrent, Vincent Maréchal, Christian Poüs, Marion Lussignol, Audrey Esclatine
Publikováno v:
PLoS Pathogens
PLoS Pathogens, 2022, 18 (3), pp.e1010371. ⟨10.1371/journal.ppat.1010371⟩
PLoS Pathogens, 2022, 18 (3), pp.e1010371. ⟨10.1371/journal.ppat.1010371⟩
Innate immunity constitutes the first line of defense against viruses, in which mitochondria play an important role in the induction of the interferon (IFN) response. BHRF1, a multifunctional viral protein expressed during Epstein-Barr virus reactiva
Autor:
Felix J. Flomm, Søren Pfitzner, Hannah M. Britt, Timothy K. Soh, Jens B. Bosse, Kay Grünewald, Carola Schneider, Konstantinos Thalassinos, Rudolph Reimer
Publikováno v:
PLoS pathogens. 18(8)
Human Cytomegalovirus (HCMV) can infect a variety of cell types by using virions of varying glycoprotein compositions. It is still unclear how this diversity is generated, but spatio-temporally separated envelopment and egress pathways might play a r
Autor:
Dan Wang, Xinxin Zhang, Liwen Yin, Qi Liu, Zhaoli Yu, Congjuan Xu, Zhenzhen Ma, Yushan Xia, Jing Shi, Yuehua Gong, Fang Bai, Zhihui Cheng, Weihui Wu, Jinzhong Lin, Yongxin Jin
Publikováno v:
PLoS Pathogens, Vol 18, Iss 1 (2022)
PLoS Pathogens, Vol 18, Iss 1, p e1010170 (2022)
PLoS Pathogens
PLoS Pathogens, Vol 18, Iss 1, p e1010170 (2022)
PLoS Pathogens
Pseudomonas aeruginosa is an important opportunistic pathogen capable of causing variety of infections in humans. The type III secretion system (T3SS) is a critical virulence determinant of P. aeruginosa in the host infections. Expression of the T3SS
Autor:
Sven Peine, Marissa Herrmann, Hendrik Karsten, Marc Lütgehetmann, Matthias Marget, Matin Kohsar, William W. Kwok, John Sidney, Janna Heide, Sophia Schulte, Alessandro Sette, Julian Schulze zur Wiesch, Alexandra M. Johansson, Thomas Theo Brehm
Publikováno v:
PLoS Pathogens, Vol 18, Iss 1 (2022)
PLoS Pathogens, Vol 17, Iss 9, p e1009842 (2021)
PLoS Pathogens
PLoS Pathogens, Vol 18, Iss 1, p e1010220 (2022)
PLoS Pathogens, Vol 17, Iss 9, p e1009842 (2021)
PLoS Pathogens
PLoS Pathogens, Vol 18, Iss 1, p e1010220 (2022)
The aim of this study was to define the breadth and specificity of dominant SARS-CoV-2-specific T cell epitopes using a comprehensive set of 135 overlapping 15-mer peptides covering the SARS-CoV-2 envelope (E), membrane (M) and nucleoprotein (N) in a
Autor:
Talita B. Gagliardi, Monty E. Goldstein, Daniel Song, Kelsey M. Gray, Jae W. Jung, Maxinne A. Ignacio, Kimberly M. Stroka, Gregg A. Duncan, Margaret A. Scull
Publikováno v:
PLoS Pathogens, Vol 18, Iss 1, p e1010159 (2022)
PLoS Pathogens
PLoS Pathogens
The clinical impact of rhinovirus C (RV-C) is well-documented; yet, the viral life cycle remains poorly defined. Thus, we characterized RV-C15 replication at the single-cell level and its impact on the human airway epithelium (HAE) using a physiologi
Autor:
Guanwei Wu, Zhaoxing Jia, Kaida Ding, Hongying Zheng, Yuwen Lu, Lin Lin, Jiejun Peng, Shaofei Rao, Aiming Wang, Jianping Chen, Fei Yan
Publikováno v:
PLoS Pathogens, Vol 18, Iss 1, p e1010257 (2022)
PLoS Pathogens
PLoS Pathogens
Accumulated experimental evidence has shown that viruses recruit the host intracellular machinery to establish infection. It has recently been shown that the potyvirus Turnip mosaic virus (TuMV) transits through the late endosome (LE) for viral genom
Autor:
Aparna Jorapur, Lisa A. Marshall, Scott Jacobson, Mengshu Xu, Sachie Marubayashi, Mikhail Zibinsky, Dennis X. Hu, Omar Robles, Jeffrey J. Jackson, Valentin Baloche, Pierre Busson, David Wustrow, Dirk G. Brockstedt, Oezcan Talay, Paul D. Kassner, Gene Cutler
Publikováno v:
PLoS Pathogens, Vol 18, Iss 1, p e1010200 (2022)
PLoS Pathogens
PLoS Pathogens
The Epstein-Barr Virus (EBV) is involved in the etiology of multiple hematologic and epithelial human cancers. EBV+ tumors employ multiple immune escape mechanisms, including the recruitment of immunosuppressive regulatory T cells (Treg). Here, we sh
Autor:
Miguel Ángel Cuesta-Geijo, Isabel García-Dorival, Ana del Puerto, Jesús Urquiza, Inmaculada Galindo, Lucía Barrado-Gil, Fátima Lasala, Ana Cayuela, Carlos Oscar S. Sorzano, Carmen Gil, Rafael Delgado, Covadonga Alonso
Publikováno v:
PLoS Pathogens, Vol 18, Iss 1, p e1009784 (2022)
PLoS Pathogens
Digital.CSIC. Repositorio Institucional del CSIC
instname
PLoS Pathogens
Digital.CSIC. Repositorio Institucional del CSIC
instname
28 p.-7 fig.-- Departamento de Biotecnología.
African swine fever virus (ASFV) infectious cycle starts with the viral adsorption and entry into the host cell. Then, the virus is internalized via clathrin/dynamin mediated endocytosis and macropi
African swine fever virus (ASFV) infectious cycle starts with the viral adsorption and entry into the host cell. Then, the virus is internalized via clathrin/dynamin mediated endocytosis and macropi