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Autor:
Eric M. Burton, Benjamin E. Gewurz
Publikováno v:
PLoS Pathogens, Vol 18, Iss 2, p e1010254 (2022)
PLoS Pathogens
PLoS Pathogens
Autor:
Felix J. Flomm, Søren Pfitzner, Hannah M. Britt, Timothy K. Soh, Jens B. Bosse, Kay Grünewald, Carola Schneider, Konstantinos Thalassinos, Rudolph Reimer
Publikováno v:
PLoS pathogens. 18(8)
Human Cytomegalovirus (HCMV) can infect a variety of cell types by using virions of varying glycoprotein compositions. It is still unclear how this diversity is generated, but spatio-temporally separated envelopment and egress pathways might play a r
Autor:
Sven Peine, Marissa Herrmann, Hendrik Karsten, Marc Lütgehetmann, Matthias Marget, Matin Kohsar, William W. Kwok, John Sidney, Janna Heide, Sophia Schulte, Alessandro Sette, Julian Schulze zur Wiesch, Alexandra M. Johansson, Thomas Theo Brehm
Publikováno v:
PLoS Pathogens, Vol 18, Iss 1 (2022)
PLoS Pathogens, Vol 17, Iss 9, p e1009842 (2021)
PLoS Pathogens
PLoS Pathogens, Vol 18, Iss 1, p e1010220 (2022)
PLoS Pathogens, Vol 17, Iss 9, p e1009842 (2021)
PLoS Pathogens
PLoS Pathogens, Vol 18, Iss 1, p e1010220 (2022)
The aim of this study was to define the breadth and specificity of dominant SARS-CoV-2-specific T cell epitopes using a comprehensive set of 135 overlapping 15-mer peptides covering the SARS-CoV-2 envelope (E), membrane (M) and nucleoprotein (N) in a
Autor:
Aparna Jorapur, Lisa A. Marshall, Scott Jacobson, Mengshu Xu, Sachie Marubayashi, Mikhail Zibinsky, Dennis X. Hu, Omar Robles, Jeffrey J. Jackson, Valentin Baloche, Pierre Busson, David Wustrow, Dirk G. Brockstedt, Oezcan Talay, Paul D. Kassner, Gene Cutler
Publikováno v:
PLoS Pathogens, Vol 18, Iss 1, p e1010200 (2022)
PLoS Pathogens
PLoS Pathogens
The Epstein-Barr Virus (EBV) is involved in the etiology of multiple hematologic and epithelial human cancers. EBV+ tumors employ multiple immune escape mechanisms, including the recruitment of immunosuppressive regulatory T cells (Treg). Here, we sh
Autor:
Miguel Ángel Cuesta-Geijo, Isabel García-Dorival, Ana del Puerto, Jesús Urquiza, Inmaculada Galindo, Lucía Barrado-Gil, Fátima Lasala, Ana Cayuela, Carlos Oscar S. Sorzano, Carmen Gil, Rafael Delgado, Covadonga Alonso
Publikováno v:
PLoS Pathogens, Vol 18, Iss 1, p e1009784 (2022)
PLoS Pathogens
Digital.CSIC. Repositorio Institucional del CSIC
instname
PLoS Pathogens
Digital.CSIC. Repositorio Institucional del CSIC
instname
28 p.-7 fig.-- Departamento de Biotecnología.
African swine fever virus (ASFV) infectious cycle starts with the viral adsorption and entry into the host cell. Then, the virus is internalized via clathrin/dynamin mediated endocytosis and macropi
African swine fever virus (ASFV) infectious cycle starts with the viral adsorption and entry into the host cell. Then, the virus is internalized via clathrin/dynamin mediated endocytosis and macropi
Autor:
Abdullah M. Izmirly, Adam-Nicolas Pelletier, Jennifer Connors, Bhavani Taramangalam, Sawsan O. Alturki, Emma A. Gordon, Sana O. Alturki, Joshua C. Mell, Gokul Swaminathan, Vivin Karthik, Michele A. Kutzler, Esper G. Kallas, Rafick-Pierre Sekaly, Elias K. Haddad
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 18, Iss 1, p e1009903 (2022)
PLoS Pathogens, Vol 18, Iss 1, p e1009903 (2022)
It has been estimated that more than 390 million people are infected with Dengue virus every year; around 96 millions of these infections result in clinical pathologies. To date, there is only one licensed viral vector-based Dengue virus vaccine CYD-
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 17, Iss 12, p e1010109 (2021)
PLoS Pathogens, Vol 17, Iss 12, p e1010109 (2021)
Publikováno v:
PLoS Pathogens, Vol 17, Iss 12, p e1009600 (2021)
PLoS Pathogens
PLoS Pathogens
Kaposi’s sarcoma (KS) is an angioproliferative and invasive tumor caused by Kaposi’s sarcoma-associated herpesvirus (KSHV). The cellular origin of KS tumor cells remains contentious. Recently, evidence has accrued indicating that KS may arise fro
Autor:
Marissa Fahlberg, Cecily C. Midkiff, Hongmei Gao, Faith Schiro, Breanna Picou, Kasi E. Russell-Lodrigue, Pyone P. Aye, Kelly Goff, Krystle Hensley, Nadia A. Golden, Rudolf P. Bohm, David C. Montefiori, Lara A. Doyle-Meyers, Nicholas J. Maness, Robert V Blair, Scott C. Weaver, Joseph L. Mankowski, Alexandra Melton, Jay Rappaport, Brandon J. Beddingfield, Dawn M. Szeltner, Chad J. Roy, Kristin E Chandler, Skye Spencer, Toni Penney, Jessica A. Plante, James A. Hoxie, Hunter J Melton, Kenneth S. Plante
Publikováno v:
PLoS Pathogens, Vol 17, Iss 12, p e1010162 (2021)
PLoS Pathogens
PLoS Pathogens
The novel coronavirus SARS-CoV-2, the causative agent of COVID-19 disease, has killed over five million people worldwide as of December 2021 with infections rising again due to the emergence of highly transmissible variants. Animal models that faithf
Autor:
Alexander C. Dowell, Tracey A. Haigh, Gordon B. Ryan, James E. Turner, Heather M. Long, Graham S. Taylor
Publikováno v:
PLoS Pathogens, Vol 17, Iss 12, p e1010137 (2021)
PLoS Pathogens
PLoS Pathogens
Epstein Barr Virus (EBV) infects more than 95% of the population whereupon it establishes a latent infection of B-cells that persists for life under immune control. Primary EBV infection can cause infectious mononucleosis (IM) and long-term viral car