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Autor:
Gregory D. Ebel, Michael C. Young, Gareth Halladay, Deedra J Murrieta, Joseph R. Fauver, James Weger-Lucarelli, Selene M. Garcia-Luna, Reyes A. Murrieta, Claudia Rückert, Alex Gendernalik
Publikováno v:
PLoS Pathogens, Vol 17, Iss 11, p e1009433 (2021)
PLoS Pathogens
PLoS Pathogens
Arthropod-borne viruses (arboviruses) require replication across a wide range of temperatures to perpetuate. While vertebrate hosts tend to maintain temperatures of approximately 37°C—40°C, arthropods are subject to ambient temperatures which can
Autor:
Peter Simmonds, M. Azim Ansari
Publikováno v:
PLoS Pathogens, Vol 17, Iss 6, p e1009596 (2021)
PLoS Pathogens
PLoS Pathogens
The rapid evolution of RNA viruses has been long considered to result from a combination of high copying error frequencies during RNA replication, short generation times and the consequent extensive fixation of neutral or adaptive changes over short
Autor:
Jonathon A. Siva-Jothy, Pedro F. Vale
Publikováno v:
PLoS Pathogens, Vol 17, Iss 1, p e1009196 (2021)
PLoS Pathogens
Siva-Jothy, J & Vale, P F D 2021, ' Dissecting genetic and sex-specific sources of host heterogeneity in pathogen shedding and spreading ', PLoS Pathogens, vol. 17, no. 1, e1009196 . https://doi.org/10.1371/journal.ppat.1009196
PLoS Pathogens
Siva-Jothy, J & Vale, P F D 2021, ' Dissecting genetic and sex-specific sources of host heterogeneity in pathogen shedding and spreading ', PLoS Pathogens, vol. 17, no. 1, e1009196 . https://doi.org/10.1371/journal.ppat.1009196
Host heterogeneity in disease transmission is widespread but precisely how different host traits drive this heterogeneity remains poorly understood. Part of the difficulty in linking individual variation to population-scale outcomes is that individua
Autor:
Kei Sato, Mahoko Takahashi Ueda, Keiya Uriu, Yusuke Kosugi, Reuben S. Harris, Yusuke Nakano, Yoshio Koyanagi, Shumpei Nagaoka, Hirofumi Aso, Keito Mitsumune, Yoriyuki Konno, Andrew Soper, Jumpei Ito, Naoko Misawa, So Nakagawa, Izumi Kimura, Terumasa Ikeda, Keisuke Yamamoto, Soma Shimizu, Guillermo Juarez-Fernandez, Ryuichi Kumata
Publikováno v:
PLoS Pathogens, Vol 16, Iss 9, p e1008812 (2020)
PLoS Pathogens
PLoS Pathogens
The APOBEC3 deaminases are potent inhibitors of virus replication and barriers to cross-species transmission. For simian immunodeficiency virus (SIV) to transmit to a new primate host, as happened multiple times to seed the ongoing HIV-1 epidemic, th
Autor:
Clement Pellegrin, Etienne Danchin, Thomas R. Maier, Lev G. Nemchinov, Sebastian Eves-van den Akker, Catherine Wram, Thomas J. Baum, Georgios Koutsovoulos, Cedar Hesse, Paulo Vieira, Jonathan Shao, Inga A. Zasada, Tracie K. Matsumoto, Roxana Y. Myers
Publikováno v:
PLoS Pathogens, Vol 17, Iss 11, p e1010036 (2021)
PLoS Pathogens
PLoS Pathogens, Vol 17, Iss 11 (2021)
PLoS Pathogens
PLoS Pathogens, Vol 17, Iss 11 (2021)
The burrowing nematode, Radopholus similis, is an economically important plant-parasitic nematode that inflicts damage and yield loss to a wide range of crops. This migratory endoparasite is widely distributed in warmer regions and causes extensive d
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 17, Iss 9, p e1009845 (2021)
PLoS Pathogens, Vol 17, Iss 9, p e1009845 (2021)
Publikováno v:
PLoS Pathogens, Vol 17, Iss 5, p e1009528 (2021)
PLoS Pathogens
PLoS Pathogens
Tradeoff theory, which postulates that virulence provides both transmission costs and benefits for pathogens, has become widely adopted by the scientific community. Although theoretical literature exploring virulence-tradeoffs is vast, empirical stud
Autor:
Shannon C. Brady, Ellen Chao, Steffen Hahnel, Briana C. Rodriguez, Erik C. Andersen, Katherine Introcaso, Grace Park, Kathryn S. Evans, Lewis Stevens, Janneke Wit, Robyn E. Tanny, Mostafa Zamanian
Publikováno v:
PLoS Pathogens, Vol 17, Iss 3, p e1009297 (2021)
PLoS Pathogens
PLoS Pathogens
Parasitic nematodes cause a massive worldwide burden on human health along with a loss of livestock and agriculture productivity. Anthelmintics have been widely successful in treating parasitic nematodes. However, resistance is increasing, and little
Autor:
Jean-François Allienne, Silvain Pinaud, Anaïs Portet, David Duval, Guillaume M. Charrière, Julien Portela, Nolwenn M. Dheilly, Richard Galinier, Cristian Chaparro, Benjamin Gourbal
Publikováno v:
PLoS Pathogens, Vol 15, Iss 3, p e1007647 (2019)
PLoS Pathogens
PLoS Pathogens, Public Library of Science, 2019, 15 (3), pp.e1007647. ⟨10.1371/journal.ppat.1007647⟩
Plos Pathogens (1553-7366) (Public Library Science), 2019-03, Vol. 15, N. 3, P. e1007647. (28p.)
PLoS Pathogens
PLoS Pathogens, Public Library of Science, 2019, 15 (3), pp.e1007647. ⟨10.1371/journal.ppat.1007647⟩
Plos Pathogens (1553-7366) (Public Library Science), 2019-03, Vol. 15, N. 3, P. e1007647. (28p.)
Selective pressures between hosts and their parasites can result in reciprocal evolution or adaptation of specific life history traits. Local adaptation of resident hosts and parasites should lead to increase parasite infectivity/virulence (higher co
Autor:
Aleyla Escueta-de Cadiz, Emi Sato-Ebine, Makoto Kuroda, Dar Der Ji, Tomoyoshi Nozaki, Tsuyoshi Sekizuka, Kumiko Nakada-Tsukui, Kentaro Tomii
Publikováno v:
PLoS Pathogens, Vol 14, Iss 3, p e1006882 (2018)
PLoS Pathogens
PLoS Pathogens, Vol 14, Iss 5, p e1007091 (2018)
PLoS Pathogens
PLoS Pathogens, Vol 14, Iss 5, p e1007091 (2018)
The disease state of amebiasis, caused by Entamoeba histolytica, varies from asymptomatic to severe manifestations that include dysentery and extraintestinal abscesses. The virulence factors of the pathogen, and host defense mechanisms, contribute to