Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Thatcher A."'
Publikováno v:
PLoS ONE, Vol 17, Iss 3, p e0245817 (2022)
The standard treatment for glioblastoma involves a combination of surgery, radiation and chemotherapy but have limited impact on survival. The exponential increase in targeted agents directed at pivotal oncogenic pathways now provide new therapeutic
Externí odkaz:
https://doaj.org/article/d07d76b81cdb4578a214ceae321c8ed6
Autor:
Marco Loddo, Keeda-Marie Hardisty, Alexander Llewelyn, Tiffany Haddow, Robert Thatcher, Gareth Williams
Publikováno v:
PLoS ONE, Vol 17, Iss 8, p e0246778 (2022)
Oncogenic fusions represent compelling druggable targets in solid tumours highlighted by the recent site agnostic FDA approval of larotrectinib for NTRK rearrangements. However screening for fusions in routinely processed tissue samples is constraine
Externí odkaz:
https://doaj.org/article/ff44c4eca87a435cbd7166f80343403a
Autor:
Kathryn M Emmerson, Jeremy D Silver, Marcus Thatcher, Alan Wain, Penelope J Jones, Andrew Dowdy, Edward J Newbigin, Beau W Picking, Jason Choi, Elizabeth Ebert, Tony Bannister
Publikováno v:
PLoS ONE, Vol 16, Iss 4, p e0249488 (2021)
The world's most severe thunderstorm asthma event occurred in Melbourne, Australia on 21 November 2016, coinciding with the peak of the grass pollen season. The aetiological role of thunderstorms in these events is thought to cause pollen to rupture
Externí odkaz:
https://doaj.org/article/41efdc90e0ae434193feaf01697170b7
Autor:
Parker F Duffney, A Karim Embong, Connor C McGuire, Thomas H Thatcher, Richard P Phipps, Patricia J Sime
Publikováno v:
PLoS ONE, Vol 15, Iss 5, p e0232102 (2020)
Cigarette smoke exposure is a risk factor for many pulmonary diseases, including Chronic Obstructive Pulmonary Disease (COPD). Cigarette smokers are more prone to respiratory infections with more severe symptoms. In those with COPD, viral infections
Externí odkaz:
https://doaj.org/article/e4efa8400677485bb41a9ba3bd6eefa9
Akademický článek
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Akademický článek
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Publikováno v:
PLoS ONE, Vol 11, Iss 5, p e0154504 (2016)
Experimental and comparative evidence suggests that the striped coats of zebras deter biting fly attack, but the mechanisms by which flies fail to target black-and-white mammals are still opaque. Two hypotheses have been proposed: stripes might serve
Externí odkaz:
https://doaj.org/article/b5a73f7f6f7f4b33831c29d91c72ce6e
Autor:
Thozhukat Sathyapalan, Natalie J Thatcher, Richard Hammersley, Alan S Rigby, Fraser L Courts, Alexandros Pechlivanis, Nigel J Gooderham, Elaine Holmes, Carel W le Roux, Stephen L Atkin
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0116212 (2015)
BackgroundAspartame is a commonly used intense artificial sweetener, being approximately 200 times sweeter than sucrose. There have been concerns over aspartame since approval in the 1980s including a large anecdotal database reporting severe symptom
Externí odkaz:
https://doaj.org/article/d40813aad0ae47938a84bab766e22596
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0126978 (2015)
Glutathione S-transferases (GSTs) play important roles in the protection of cells against toxins and oxidative damage where one Arabidopsis member, GSTF8, has become a commonly used marker gene for early stress and defense responses. A GSTF8 promoter
Externí odkaz:
https://doaj.org/article/33f74e5e15ce44a4b9062c560d2e4d44
Autor:
Amali P Epa, Thomas H Thatcher, Stephen J Pollock, Lindsay A Wahl, Elizabeth Lyda, R M Kottmann, Richard P Phipps, Patricia J Sime
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0135266 (2015)
INTRODUCTION:Idiopathic pulmonary fibrosis (IPF) is a chronic progressive disease with very few effective treatments. The key effector cells in fibrosis are believed to be fibroblasts, which differentiate to a contractile myofibroblast phenotype with
Externí odkaz:
https://doaj.org/article/add295e12d964b9cb506b33c13033749