Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Maria R. Baer"'
Autor:
Maria R. Baer, Suneet Shukla, Jasjeet Bhullar, Karthika Natarajan, Trevor J. Mathias, Suresh V. Ambudkar, Mariola Sadowska
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e71266 (2013)
PLoS ONE
PLoS ONE
The oral second-generation bis-aryl urea fms-like tyrosine kinase 3 (FLT3) inhibitor quizartinib (AC220) has favorable kinase selectivity and pharmacokinetics. It inhibits mutant and wild-type FLT3 in vivo at 0.1 and 0.5 µM, respectively, and has sh
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 9, p e74653 (2013)
PLoS ONE, Vol 8, Iss 9, p e74653 (2013)
The type III receptor tyrosine kinase fms-like tyrosine kinase 3 (FLT3) is expressed on both normal hematopoietic stem cells and acute myeloid leukemia (AML) cells and regulates their proliferation. Internal tandem duplication (ITD) mutation of FLT3
Autor:
Brianne Teaboldt, Kara A. Scheibner, Shelly Heimfeld, Curt I. Civin, Shannon M. Kelley, Zhenqiu Liu, Mary Claire Hauer, Xiaochun Chen, Yin Guo, Maria R. Baer, Srujana Cherukuri
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e50895 (2012)
PLoS ONE
PLoS ONE
MicroRNAs (miRs) play major roles in normal hematopoietic differentiation and hematopoietic malignancies. In this work, we report that miR-27a, and its coordinately expressed cluster (miR-23a∼miR-27a∼miR-24-2), was down-regulated in acute leukemi
Autor:
Jasjeet Bhullar, Karthika Natarajan, Suneet Shukla, Trevor J Mathias, Mariola Sadowska, Suresh V Ambudkar, Maria R Baer
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e71266 (2013)
The oral second-generation bis-aryl urea fms-like tyrosine kinase 3 (FLT3) inhibitor quizartinib (AC220) has favorable kinase selectivity and pharmacokinetics. It inhibits mutant and wild-type FLT3 in vivo at 0.1 and 0.5 µM, respectively, and has sh
Externí odkaz:
https://doaj.org/article/ab5b8f0484cd41be89e70542266bb8b9
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e74653 (2013)
The type III receptor tyrosine kinase fms-like tyrosine kinase 3 (FLT3) is expressed on both normal hematopoietic stem cells and acute myeloid leukemia (AML) cells and regulates their proliferation. Internal tandem duplication (ITD) mutation of FLT3
Externí odkaz:
https://doaj.org/article/e803b2ac63df4c3e9c2b7a6898ffd48f
Autor:
Kara A Scheibner, Brianne Teaboldt, Mary Claire Hauer, Xiaochun Chen, Srujana Cherukuri, Yin Guo, Shannon M Kelley, Zhenqiu Liu, Maria R Baer, Shelly Heimfeld, Curt I Civin
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e50895 (2012)
MicroRNAs (miRs) play major roles in normal hematopoietic differentiation and hematopoietic malignancies. In this work, we report that miR-27a, and its coordinately expressed cluster (miR-23a∼miR-27a∼miR-24-2), was down-regulated in acute leukemi
Externí odkaz:
https://doaj.org/article/f3f653cf4b9b49d29412744869333db9