Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Gary S Gilkeson"'
Autor:
Bahram Namjou, Xana Kim-Howard, Celi Sun, Adam Adler, Sharon A Chung, Kenneth M Kaufman, Jennifer A Kelly, Stuart B Glenn, Joel M Guthridge, Robert H Scofield, Robert P Kimberly, Elizabeth E Brown, Graciela S Alarcón, Jeffrey C Edberg, Jae-Hoon Kim, Jiyoung Choi, Rosalind Ramsey-Goldman, Michelle A Petri, John D Reveille, Luis M Vilá, Susan A Boackle, Barry I Freedman, Betty P Tsao, Carl D Langefeld, Timothy J Vyse, Chaim O Jacob, Bernardo Pons-Estel, Argentine Collaborative Group, Timothy B Niewold, Kathy L Moser Sivils, Joan T Merrill, Juan-Manuel Anaya, Gary S Gilkeson, Patrick M Gaffney, Sang-Cheol Bae, Marta E Alarcón-Riquelme, BIOLUPUS and GENLES Networks, John B Harley, Lindsey A Criswell, Judith A James, Swapan K Nath
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e69404 (2013)
Protein tyrosine phosphatase non-receptor type 22 (PTPN22) is a negative regulator of T-cell activation associated with several autoimmune diseases, including systemic lupus erythematosus (SLE). Missense rs2476601 is associated with SLE in individual
Externí odkaz:
https://doaj.org/article/7f544fb4ff94405a99392c0cc98528bd
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e64650 (2013)
Systemic lupus erythematosus, in both animal models and in humans, is characterized by autoantibody production followed by immune complex deposition in target tissues. Ensuing target organ damage is modulated by reactive intermediates, including reac
Externí odkaz:
https://doaj.org/article/f925e42c91d84ea38b2cb0be76b41cf4
Autor:
Ilan Ben-Zvi, Cynthia Aranow, Meggan Mackay, Anfisa Stanevsky, Diane L Kamen, L Manuela Marinescu, Christopher E Collins, Gary S Gilkeson, Betty Diamond, John A Hardin
Publikováno v:
PLoS ONE, Vol 5, Iss 2, p e9193 (2010)
Excessive activity of dendritic cells (DCs) is postulated as a central disease mechanism in Systemic Lupus Erythematosus (SLE). Vitamin D is known to reduce responsiveness of healthy donor DCs to the stimulatory effects of Type I IFN. As vitamin D de
Externí odkaz:
https://doaj.org/article/b249c53d0a5441e1948b59a9379f318b
Autor:
Shizhong Han, Joel M Guthridge, Isaac T W Harley, Andrea L Sestak, Xana Kim-Howard, Kenneth M Kaufman, Bahram Namjou, Harshal Deshmukh, Gail Bruner, Luis R Espinoza, Gary S Gilkeson, John B Harley, Judith A James, Swapan K Nath
Publikováno v:
PLoS ONE, Vol 3, Iss 3, p e0001757 (2008)
Osteopontin (SPP1) is an important bone matrix mediator found to have key roles in inflammation and immunity. SPP1 genetic polymorphisms and increased osteopontin protein levels have been reported to be associated with SLE in small patient collection
Externí odkaz:
https://doaj.org/article/e291051d6aea40bc92ed01d7fb7fa7bc
Autor:
Amr H Sawalha, Ryan Webb, Shizhong Han, Jennifer A Kelly, Kenneth M Kaufman, Robert P Kimberly, Marta E Alarcón-Riquelme, Judith A James, Timothy J Vyse, Gary S Gilkeson, Chan-Bum Choi, R Hal Scofield, Sang-Cheol Bae, Swapan K Nath, John B Harley
Publikováno v:
PLoS ONE, Vol 3, Iss 3, p e1727 (2008)
Systemic lupus erythematosus (SLE) is a predominantly female autoimmune disease that affects multiple organ systems. Herein, we report on an X-chromosome gene association with SLE. Methyl-CpG-binding protein 2 (MECP2) is located on chromosome Xq28 an
Externí odkaz:
https://doaj.org/article/3951a4f4528f4e5395924a8e5de16241
Autor:
Jessalyn Rodgers, Ivan Molano, Tamara K. Nowling, Kamala P. Sundararaj, Thirumagal Thiyagarajan, Bethany J. Wolf, Gary S. Gilkeson, Evelyn Bruner
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 3, p e0230499 (2020)
PLoS ONE, Vol 15, Iss 3, p e0230499 (2020)
Glycosphingolipids (GSLs) hexosylceramides and lactosylceramides are elevated in lupus mice and human patients with nephritis. Whereas other renal diseases characterized by increased GSL levels are thought to be a result of upregulated GSL synthesis,
Autor:
Luis M. Vilá, Juan-Manuel Anaya, Bahram Namjou, Graciela S. Alarcón, John B. Harley, Jeffrey C. Edberg, Marta E. Alarcón-Riquelme, Elizabeth E. Brown, R. H. Scofield, Timothy B. Niewold, Jiyoung Choi, Carl D. Langefeld, Robert P. Kimberly, Barry I. Freedman, Betty P. Tsao, Swapan K. Nath, Jennifer A. Kelly, Bernardo A. Pons-Estel, John D. Reveille, Kenneth M. Kaufman, Joel M. Guthridge, Kathy L. Sivils, Susan A. Boackle, Judith A. James, Timothy J. Vyse, Patrick M. Gaffney, Lindsey A. Criswell, Jaehoon Kim, Sharon A. Chung, Chaim O. Jacob, Michelle Petri, Sang Cheol Bae, Joan T. Merrill, Adam Adler, Stuart B. Glenn, Xana Kim-Howard, Rosalind Ramsey-Goldman, Celi Sun, Gary S. Gilkeson
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 8, p e69404 (2013)
Repositorio EdocUR-U. Rosario
Universidad del Rosario
instacron:Universidad del Rosario
PLoS ONE, Vol 8, Iss 8, p e69404 (2013)
Repositorio EdocUR-U. Rosario
Universidad del Rosario
instacron:Universidad del Rosario
Protein tyrosine phosphatase non-receptor type 22 (PTPN22) is a negative regulator of T-cell activation associated with several autoimmune diseases, including systemic lupus erythematosus (SLE). Missense rs2476601 is associated with SLE in individual
Autor:
Isaac T.W. Harley, Swapan K. Nath, Kenneth M. Kaufman, Judith A. James, Joel M. Guthridge, John B. Harley, Xana Kim-Howard, Harshal Deshmukh, Andrea L. Sestak, Gail R. Bruner, Bahram Namjou, Shizhong Han, Gary S. Gilkeson, Luis R. Espinoza
Publikováno v:
PLoS ONE
PLoS ONE, Vol 3, Iss 3, p e0001757 (2008)
PLoS ONE, Vol 3, Iss 3, p e0001757 (2008)
Osteopontin (SPP1) is an important bone matrix mediator found to have key roles in inflammation and immunity. SPP1 genetic polymorphisms and increased osteopontin protein levels have been reported to be associated with SLE in small patient collection
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e114589 (2014)
PLoS ONE
PLoS ONE
Introduction TLR7/8 and TLR9 signaling pathways have been extensively studied in systemic lupus erythematosus (SLE) as possible mediators of disease. Monocytes are a major source of pro-inflammatory cytokines and are understudied in SLE. In the curre
Autor:
Kenneth M. Kaufman, Judith A. James, Marta E. Alarcón-Riquelme, Shizhong Han, Robert P. Kimberly, Chan-Bum Choi, Jennifer A. Kelly, John B. Harley, R. Hal Scofield, Ryan Webb, Timothy J. Vyse, Sang Cheol Bae, Gary S. Gilkeson, Swapan K. Nath, Amr H. Sawalha
Publikováno v:
PLoS ONE
PLoS ONE, Vol 3, Iss 3, p e1727 (2008)
PLoS ONE, Vol 3, Iss 3, p e1727 (2008)
Systemic lupus erythematosus (SLE) is a predominantly female autoimmune disease that affects multiple organ systems. Herein, we report on an X-chromosome gene association with SLE. Methyl-CpG-binding protein 2 (MECP2) is located on chromosome Xq28 an