Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Elizabeth M. Jaffee"'
Autor:
Aditya Mohan, Mark Yarchoan, Elizabeth M. Jaffee, Nilofer S. Azad, Amanda Ruggieri, Gregory B. Lesinski, Teena Vithayathil, Todd D. Armstrong, Lauren Dennison
Publikováno v:
PLoS ONE
PLoS ONE, Vol 14, Iss 10, p e0224600 (2019)
PLoS ONE, Vol 14, Iss 10, p e0224600 (2019)
Mitogen-activated protein kinase (MAPK) kinase (MEK) is an integral component of the RAS pathway and a therapeutic target in RAS-driven cancers. Although tumor responses to MEK inhibition are rarely durable, MEK inhibitors have shown substantial acti
Autor:
George Sgouros, Todd D. Armstrong, Elizabeth M. Jaffee, Timothy H. Lee, Chelsea M. Black, Theodore Kouo, Hong Song, Vivian L. Weiss
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e31962 (2012)
PLoS ONE
PLoS ONE
Background Cancer vaccines are designed to activate and enhance cancer-antigen-targeted T cells that are suppressed through multiple mechanisms of immune tolerance in cancer-bearing hosts. T regulatory cell (Treg) suppression of tumor-specific T cell
Autor:
Lanqing Huang, Robert A. Anders, Lei Zheng, Jennifer E. Van Eyk, Dung T. Le, Rajni Sharma, Ashley Leubner, Masamichi Mizuma, Barish H. Edil, Peter B. Illei, Kelly Olino, Elizabeth M. Jaffee, Anirban Maitra, Guanglan Mo, Daniel A. Laheru, Kelly Foley
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e19390 (2011)
PLoS ONE
PLoS ONE
The aggressiveness of pancreatic ductal adenocarcinoma (PDA) is characterized by its high metastatic potential and lack of effective therapies, which is the result of a lack of understanding of the mechanisms involved in promoting PDA metastases. We
Autor:
Mark Yarchoan, Aditya A Mohan, Lauren Dennison, Teena Vithayathil, Amanda Ruggieri, Gregory B Lesinski, Todd D Armstrong, Nilofer S Azad, Elizabeth M Jaffee
Publikováno v:
PLoS ONE, Vol 14, Iss 10, p e0224600 (2019)
Mitogen-activated protein kinase (MAPK) kinase (MEK) is an integral component of the RAS pathway and a therapeutic target in RAS-driven cancers. Although tumor responses to MEK inhibition are rarely durable, MEK inhibitors have shown substantial acti
Externí odkaz:
https://doaj.org/article/deeb6c87dad04ce283915d1ea8fb3199
Autor:
Kimberline Y Gerrick, Elias R Gerrick, Anuj Gupta, Sarah J Wheelan, Srinivasan Yegnasubramanian, Elizabeth M Jaffee
Publikováno v:
PLoS ONE, Vol 13, Iss 12, p e0208602 (2018)
Macrophages are key inflammatory immune cells that display dynamic phenotypes and functions in response to their local microenvironment. Major advances have occurred in understanding the transcriptional, epigenetic, and functional differences in vari
Externí odkaz:
https://doaj.org/article/9fa4135bf2d9403484c5728d477ff71c
Autor:
Vivian L Weiss, Timothy H Lee, Hong Song, Theodore S Kouo, Chelsea M Black, George Sgouros, Elizabeth M Jaffee, Todd D Armstrong
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e31962 (2012)
Cancer vaccines are designed to activate and enhance cancer-antigen-targeted T cells that are suppressed through multiple mechanisms of immune tolerance in cancer-bearing hosts. T regulatory cell (Treg) suppression of tumor-specific T cells is one ba
Externí odkaz:
https://doaj.org/article/8e03c679d1a24ecb8ea89378e05b17c2
Autor:
Lei Zheng, Kelly Foley, Lanqing Huang, Ashley Leubner, Guanglan Mo, Kelly Olino, Barish H Edil, Masamichi Mizuma, Rajni Sharma, Dung T Le, Robert A Anders, Peter B Illei, Jennifer E Van Eyk, Anirban Maitra, Daniel Laheru, Elizabeth M Jaffee
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e19390 (2011)
The aggressiveness of pancreatic ductal adenocarcinoma (PDA) is characterized by its high metastatic potential and lack of effective therapies, which is the result of a lack of understanding of the mechanisms involved in promoting PDA metastases. We
Externí odkaz:
https://doaj.org/article/676fb71067e54a059241229da6941bc0