Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Alanna C. Morrison"'
Autor:
Chloé Sarnowski, Han Chen, Mary L Biggs, Sylvia Wassertheil-Smoller, Jan Bressler, Marguerite R Irvin, Kathleen A Ryan, David Karasik, Donna K Arnett, L Adrienne Cupples, David W Fardo, Stephanie M Gogarten, Benjamin D Heavner, Deepti Jain, Hyun Min Kang, Charles Kooperberg, Arch G Mainous, Braxton D Mitchell, Alanna C Morrison, Jeffrey R O'Connell, Bruce M Psaty, Kenneth Rice, Albert V Smith, Ramachandran S Vasan, B Gwen Windham, Douglas P Kiel, Joanne M Murabito, Kathryn L Lunetta, TOPMed Longevity and Healthy Aging Working Group, from the NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium
Publikováno v:
PLoS ONE, Vol 16, Iss 7, p e0253611 (2021)
Handgrip strength is a widely used measure of muscle strength and a predictor of a range of morbidities including cardiovascular diseases and all-cause mortality. Previous genome-wide association studies of handgrip strength have focused on common va
Externí odkaz:
https://doaj.org/article/c6f9d153af14487282b1e003198122ed
Autor:
Han Chen, Braxton D. Mitchell, Charles Kooperberg, TOPMed Longevity, Kenneth Rice, Kathleen A. Ryan, David W. Fardo, Hyun Min Kang, Alanna C. Morrison, Arch G. Mainous, Jeffrey R. O'Connell, Albert V. Smith, Stephanie M. Gogarten, Ramachandran S. Vasan, Jan Bressler, Donna K. Arnett, Sylvia Wassertheil-Smoller, Joanne M. Murabito, Deepti Jain, B. Gwen Windham, Kathryn L. Lunetta, Benjamin D. Heavner, L. Adrienne Cupples, Mary L. Biggs, David Karasik, Bruce M. Psaty, Marguerite R. Irvin, Chloé Sarnowski, Douglas P. Kiel
Publikováno v:
PLoS ONE, Vol 16, Iss 7, p e0253611 (2021)
PLoS ONE
PLoS ONE
Handgrip strength is a widely used measure of muscle strength and a predictor of a range of morbidities including cardiovascular diseases and all-cause mortality. Previous genome-wide association studies of handgrip strength have focused on common va
Autor:
Jose-Miguel Yamal, Michael R. Brown, Deborah Banerjee, Dritana Marko Serbo, Matt D. Gunther, Paul S. de Vries, Dania Mofleh, Robert Murphy, Nick Bonvino, Qiang Wei, Farhaan S Vahidy, Warren Clifford, Eric Boerwinkle, Jemima C. John, Jennifer Kiger, Alanna C. Morrison, Shreela V. Sharma, Angela Merchant, Hua Xu, Jenny Mikhail, Ryan Ramphul, Rachel D. Harris, Marcia C de Oliveira Otto, Guillermo A. Tortolero, David Aguilar
Publikováno v:
PLoS ONE, Vol 16, Iss 6, p e0247235 (2021)
PLoS ONE
PLoS ONE
Understanding sociodemographic, behavioral, clinical, and laboratory risk factors in patients diagnosed with COVID-19 is critically important, and requires building large and diverse COVID-19 cohorts with both retrospective information and prospectiv
Autor:
J. Wouter Jukema, Jennifer A. Brody, Wolfgang Koenig, Patricia A. Peyser, Graciela Delgado, André G. Uitterlinden, Yii-Der Ida Chen, Jennifer A. Smith, Bruce M. Psaty, Suzette J. Bielinski, Naveed Sattar, Rasika A. Mathias, Lawrence F. Bielak, Kent D. Taylor, Jie Yao, George Davey Smith, Jack Bowden, Moniek P.M. de Maat, Diane M. Becker, Tim Kacprowski, Konstantin Strauch, Weihong Tang, Paul M. Ridker, Kerri L. Wiggins, Yi-Ping Fu, Russell P. Tracy, Cavin K. Ward-Caviness, Stella Trompet, Astrid Petersman, Lisa R. Yanek, Eric Boerwinkle, Franco Giulianini, Annette Peters, Ci Song, Barbara McKnight, Jennifer E. Huffman, Fernando Pires Hartwig, Winfried März, Xiuqing Guo, Paul S. de Vries, Lewis C. Becker, Alanna C. Morrison, Stefan Gross, Thomas Meitinger, Nicholas L. Smith, Melanie Waldenberger, Abbas Dehghan, Marcus Dörr, Marcus E. Kleber, Christopher J. O'Donnell, Sharon L.R. Kardia, Nathan Pankratz, Andrew D. Johnson, Daniel I. Chasman, Oscar H. Franco, Gibran Hemani, Jerome I. Rotter, Martina Muller-Nuraysid
Publikováno v:
PLoS ONE, Vol 14, Iss 5, p e0216222 (2019)
PloS one, vol 14, iss 5
PLoS One (online), 14(5):e0216222. Public Library of Science
PLoS ONE
PLoS ONE, 14(5). PUBLIC LIBRARY SCIENCE
Ward-Caviness, C K, S. de Vries, P, Davey Smith, G, Hartwig, F, Bowden, J, Hemani, G & et al. 2019, ' Mendelian randomization evaluation of causal effects of fibrinogen on incident coronary heart disease ', PLoS ONE, vol. 14, no. 5, e0216222 . https://doi.org/10.1371/journal.pone.0216222
PloS one, vol 14, iss 5
PLoS One (online), 14(5):e0216222. Public Library of Science
PLoS ONE
PLoS ONE, 14(5). PUBLIC LIBRARY SCIENCE
Ward-Caviness, C K, S. de Vries, P, Davey Smith, G, Hartwig, F, Bowden, J, Hemani, G & et al. 2019, ' Mendelian randomization evaluation of causal effects of fibrinogen on incident coronary heart disease ', PLoS ONE, vol. 14, no. 5, e0216222 . https://doi.org/10.1371/journal.pone.0216222
Background: Fibrinogen is an essential hemostatic factor and cardiovascular disease risk factor. Early attempts at evaluating the causal effect of fibrinogen on coronary heart disease (CHD) and myocardial infraction (MI) using Mendelian randomization
Autor:
Kit Sing Au, Allison E. Ashley-Koch, Michael R. Brown, Hope Northrup, Luke Hebert, Paul Hillman, Alanna C. Morrison, Craig Baker, James E. Hixson
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 9, p e0239083 (2020)
PLoS ONE, Vol 15, Iss 9, p e0239083 (2020)
Genes in the noncanonical WNT signaling pathway controlling planar cell polarity have been linked to the neural tube defect myelomeningocele. We hypothesized that some genes in the WNT signaling network have a higher mutational burden in myelomeningo
Autor:
Eric Boerwinkle, Alon Keinan, Xiaoming Liu, Alanna C. Morrison, Haley Hunter-Zinck, Donna M. Muzny, Andrew G. Clark, Ran Blekhman, Andrew D. Johnson, Joshua C. Bis, Jin Yu, Diana Chang, Leonardo Arbiza, Srilakshmi M. Raj, Cris Van Hout, Jian Lu, Bruce M. Psaty, Richard A. Gibbs, Fuli Yu, Elodie Gazave, L. Adrienne Cupples
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0121644 (2015)
PLoS ONE
PLoS ONE
Whole genome analysis in large samples from a single population is needed to provide adequate power to assess relative strengths of natural selection across different functional components of the genome. In this study, we analyzed next-generation seq
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0133031 (2015)
PLoS ONE
PLoS ONE
Blood pressure (BP) is a heritable trait with multiple environmental and genetic contributions, with current heritability estimates from twin and family studies being ~ 40%. Here, we use genome-wide polymorphism data from the Atherosclerosis Risk in
Autor:
Bernd Meibohm, Nadia N. Hansel, Medea Imboden, Susan R. Heckbert, Stephen B. Kritchevsky, Henry Völzke, María Soler Artigas, Jerome I. Rotter, Ivan Curjuric, Daan W. Loth, Albert Hofman, Guy Brusselle, Vilmundur Gudnason, R. Graham Barr, George T. O'Connor, Matthew Kowgier, Thomas Lumley, Jemma B. Wilk, J Hansen, Tamara B. Harris, Stefan Karrasch, Bruno H. Stricker, Wei Gao, Alan James, Xiangjun Gu, David P. Strachan, Martin D. Tobin, Joachim Heinrich, Myriam Fornage, Yongmei Liu, Gail Davies, Alanna C. Morrison, Akshay Sood, Lyle J. Palmer, Alexander Teumer, Millennia Foy, Bill Musk, Holger Schulz, Patricia A. Cassano, Guo Li, O. Dale Williams, Lenore J. Launer, Michael Allerhand, Bruce M. Psaty, Melinda C. Aldrich, Lars Lind, Fernando Rivadeneira, David Couper, Kurt Lohman, Sven Gläser, Emily Hodge, Bonnie R. Joubert, Rasika A. Mathias, John M. Starr, Lies Lahousse, Tove Fall, Kathleen C. Barnes, Erik Ingelsson, Stephanie J. London, Ian J. Deary, Martin T. Wells, Kari E. North, Ashok Kumar, Arend Voorman, Eva Albrecht, Wendy L. McArdle, Albert V. Smith, Ingo Ruczinski, Beate Koch, Josée Dupuis, Nicole Probst-Hensch, Nora Franceschini, Lewis J. Smith, Dana B. Hancock, Wenbo Tang, Ian P. Hall, Sina A. Gharib, Louise V. Wain, Andrew P. Morris, André G. Uitterlinden, Cecilia M. Lindgren
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e100776 (2014)
PLoS ONE
PLOS ONE
PloS one, vol 9, iss 7
Tang, W, Kowgier, M, Loth, D W, Soler Artigas, M, Joubert, B R, Hodge, E, Gharib, S A, Smith, A V, Ruczinski, I, Gudnason, V, Mathias, R A, Harris, T B, Hansel, N N, Launer, L J, Barnes, K C, Hansen, J G, Albrecht, E, Aldrich, M C, Allerhand, M, Barr, R G, Brusselle, G G, Couper, D J, Curjuric, I, Davies, G, Deary, I J, Dupuis, J, Fall, T, Foy, M, Franceschini, N, Gao, W, Gläser, S, Gu, X, Hancock, D B, Heinrich, J, Hofman, A, Imboden, M, Ingelsson, E, James, A, Karrasch, S, Koch, B, Kritchevsky, S B, Kumar, A, Lahousse, L, Li, G, Lind, L, Lindgren, C, Liu, Y, Lohman, K, Lumley, T, McArdle, W L, Meibohm, B, Morris, A P, Morrison, A C, Musk, B, North, K E, Palmer, L J, Probst-Hensch, N M, Psaty, B M, Rivadeneira, F, Rotter, J I, Schulz, H, Smith, L J, Sood, A, Starr, J M, Strachan, D P, Teumer, A, Uitterlinden, A G, Völzke, H, Voorman, A, Wain, L V, Wells, M T, Wilk, J B, Williams, O D, Heckbert, S R, Stricker, B H, London, S J, Fornage, M, Hall, I P & Cassano, P A 2014, ' Large-scale genome-wide association studies and meta-analyses of longitudinal change in adult lung function ', PLoS ONE, vol. 9, no. 7, pp. e100776 . https://doi.org/10.1371/journal.pone.0100776
PLoS One (print), 9(7). Public Library of Science
PLoS ONE
PLOS ONE
PloS one, vol 9, iss 7
Tang, W, Kowgier, M, Loth, D W, Soler Artigas, M, Joubert, B R, Hodge, E, Gharib, S A, Smith, A V, Ruczinski, I, Gudnason, V, Mathias, R A, Harris, T B, Hansel, N N, Launer, L J, Barnes, K C, Hansen, J G, Albrecht, E, Aldrich, M C, Allerhand, M, Barr, R G, Brusselle, G G, Couper, D J, Curjuric, I, Davies, G, Deary, I J, Dupuis, J, Fall, T, Foy, M, Franceschini, N, Gao, W, Gläser, S, Gu, X, Hancock, D B, Heinrich, J, Hofman, A, Imboden, M, Ingelsson, E, James, A, Karrasch, S, Koch, B, Kritchevsky, S B, Kumar, A, Lahousse, L, Li, G, Lind, L, Lindgren, C, Liu, Y, Lohman, K, Lumley, T, McArdle, W L, Meibohm, B, Morris, A P, Morrison, A C, Musk, B, North, K E, Palmer, L J, Probst-Hensch, N M, Psaty, B M, Rivadeneira, F, Rotter, J I, Schulz, H, Smith, L J, Sood, A, Starr, J M, Strachan, D P, Teumer, A, Uitterlinden, A G, Völzke, H, Voorman, A, Wain, L V, Wells, M T, Wilk, J B, Williams, O D, Heckbert, S R, Stricker, B H, London, S J, Fornage, M, Hall, I P & Cassano, P A 2014, ' Large-scale genome-wide association studies and meta-analyses of longitudinal change in adult lung function ', PLoS ONE, vol. 9, no. 7, pp. e100776 . https://doi.org/10.1371/journal.pone.0100776
PLoS One (print), 9(7). Public Library of Science
BACKGROUND: Genome-wide association studies (GWAS) have identified numerous loci influencing cross-sectional lung function, but less is known about genes influencing longitudinal change in lung function.METHODS: We performed GWAS of the rate of chang
Autor:
James E. Hixson, Lawrence C. Shimmin, Jennifer A. Smith, Lawrence F. Bielak, Alanna C. Morrison, Linda M. Polfus, Patricia A. Peyser, Sharon L.R. Kardia
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 10, p e74642 (2013)
PLoS ONE, Vol 8, Iss 10, p e74642 (2013)
Many GWAS have identified novel loci associated with common diseases, but have focused only on main effects of individual genetic variants rather than interactions with environmental factors (GxE). Identification of GxE interactions is particularly i
Autor:
Alanna C. Morrison, Carla A. Martinez, Kit Sing Au, Hope Northrup, Jack M. Fletcher, Paul T. Cirino, Catherine J. Spellicy, Maureen Dennis
Publikováno v:
PLoS ONE
PLoS ONE, Vol 7, Iss 12, p e51330 (2012)
PLoS ONE, Vol 7, Iss 12, p e51330 (2012)
The objective of this study was to examine the relation between the 5, 10-methylenetetrahydrofolate reductase (MTHFR) gene and behaviors related to attention- deficit/hyperactivity disorder (ADHD) in individuals with myelomeningocele. The rationale f