Zobrazeno 241 - 250
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pro vyhledávání: ''
Autor:
Shin Aizawa, Akiko Ohashi, Tomihisa Takahashi, Hiroyuki Hasegawa, Masako Naito, Tomonori Harada, Yusuke Saeki
Publikováno v:
PLoS ONE
PLoS ONE, Vol 11, Iss 10, p e0164305 (2016)
PLoS ONE, Vol 11, Iss 10, p e0164305 (2016)
Tetrahydrobiopterin (BH4) is an essential cofactor of nitric oxide synthase (NOS) and aromatic amino acid hydroxylases. BH4 and 7,8-dihydrobiopterin (BH2) are metabolically interchangeable at the expense of NADPH. Exogenously administered BH4 can be
Autor:
Lennart Hammarström, Harold Marcotte, Yin Lin, Kasper Krogh-Andersen, Julien Pelletier, Claes-Göran Östenson
Publikováno v:
PLoS ONE
PLoS ONE, Vol 11, Iss 9, p e0162733 (2016)
PLoS ONE, Vol 11, Iss 9, p e0162733 (2016)
Glucagon-like peptide-1 (GLP-1) is an incretin hormone produced by intestinal cells and stimulates insulin secretion from the pancreas in a glucose-dependent manner. Exogenously supplied GLP-1 analogues are used in the treatment of type 2 diabetes. A
Autor:
Donna B. Stolz, Anne Orr, William C. Bowen, Amantha Michalopoulos, George K. Michalopoulos, Michael Q. Ding
Publikováno v:
PLoS ONE
PLoS ONE, Vol 9, Iss 4, p e95487 (2014)
PLoS ONE, Vol 9, Iss 4, p e95487 (2014)
Chemically defined serum-free media for rat hepatocytes have been useful in identifying EGFR ligands and HGF/MET signaling as direct mitogenic factors for rat hepatocytes. The absence of such media for mouse hepatocytes has prevented screening for di
Autor:
Caroline Chevarin, Sandrine Barthélémy, Michel Hamon, Sylvie Bourgoin, Saïd M'Dahoma, Didier Orsal, Valérie Kayser, Farah Chali
Publikováno v:
PLoS ONE
PLoS ONE, Public Library of Science, 2014, 9 (7), pp.e102027. ⟨10.1371/journal.pone.0102027⟩
PLoS ONE, 2014, 9 (7), pp.e102027. ⟨10.1371/journal.pone.0102027⟩
PLoS ONE, Vol 9, Iss 7, p e102027 (2014)
PLoS ONE, Public Library of Science, 2014, 9 (7), pp.e102027. 〈10.1371/journal.pone.0102027〉
PLoS ONE, Public Library of Science, 2014, 9 (7), pp.e102027. ⟨10.1371/journal.pone.0102027⟩
PLoS ONE, 2014, 9 (7), pp.e102027. ⟨10.1371/journal.pone.0102027⟩
PLoS ONE, Vol 9, Iss 7, p e102027 (2014)
PLoS ONE, Public Library of Science, 2014, 9 (7), pp.e102027. 〈10.1371/journal.pone.0102027〉
International audience; In humans, spinal cord lesions induce not only major motor and neurovegetative deficits but also severe neuropathic pain which is mostly resistant to classical analgesics. Better treatments can be expected from precise charact
Autor:
Silvia Guatimosim, Cibele Rocha-Resende, Marina Ladeira, Robson A.S. Santos, Marcos B. Melo, Denis D. Damasceno, Pedro W.M. Almeida, Mariana Gavioli, Augusto Martins Lima, Marco Antônio Peliky Fontes, Aline Lara, Marco A. M. Prado, Rodrigo R. Resende, Patrícia Massara Martinelli, Patricia Chakur Brum
Publikováno v:
PLoS ONE
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
PLoS ONE, Vol 9, Iss 7, p e100179 (2014)
Anatomy and Cell Biology Publications
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
PLoS ONE, Vol 9, Iss 7, p e100179 (2014)
Anatomy and Cell Biology Publications
Cholinergic control of the heart is exerted by two distinct branches; the autonomic component represented by the parasympathetic nervous system, and the recently described non-neuronal cardiomyocyte cholinergic machinery. Previous evidence has shown
Autor:
Takaji Yajima, Megumi Matsumoto, Hiroshi Hara, Ryo Inoue, Tomohiro Mitani, Masako Yajima, Masahito Hagio
Publikováno v:
PLoS ONE
PLoS ONE, Vol 9, Iss 4, p e93529 (2014)
PLoS ONE, Vol 9, Iss 4, p e93529 (2014)
To evaluate the effects of lutein-fortified milk administration on running exercise, a voluntary wheel-running model was performed in rats. Four-week-old F344 rats were administered test milk (10 mL/kg) daily following a 4-h fasting period, and their
The impact of adult vitamin D deficiency on behaviour and brain function in male Sprague-Dawley rats
Autor:
Karly M. Turner, John J. McGrath, Darryl W. Eyles, Meggie Voogt, Thomas H. J. Burne, Jacqueline H. Byrne
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 8, p e71593 (2013)
PLoS ONE, Vol 8, Iss 8, p e71593 (2013)
BackgroundVitamin D deficiency is common in the adult population, and this has been linked to depression and cognitive outcomes in clinical populations. The aim of this study was to investigate the effects of adult vitamin D (AVD) deficiency on behav
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e57396 (2013)
PLoS ONE
PLoS ONE
Additional somatosensory contact of preterm human infants improves a variety of developmental assessment scores, but less is known about its lasting consequences. In rodents, maternal contact may influence the programming of juvenile social play beha
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e79226 (2013)
PLoS ONE
PLoS ONE
Sildenafil citrate (Viagra), a phosphodiesterase 5 inhibitor (PDE5i), is a commonly prescribed drug for erectile dysfunction. Since the introduction of Viagra in 1997, several case reports have linked Viagra to sudden sensorineural hearing loss. Howe
Autor:
Una-Jovana Vajic, Zoran Miloradovic, Djurdjica Jovovic, Jasmina Markovic-Lipkovski, Nevena Mihailovic-Stanojevic, Jelica Grujic-Milanovic, Maja Zivotic, Milan Ivanov, Danijela Karanovic
Publikováno v:
PLoS One
PLoS ONE, Vol 11, Iss 8, p e0161706 (2016)
PLoS ONE
PLoS ONE, Vol 11, Iss 8, p e0161706 (2016)
PLoS ONE
Oxidative stress has been widely implicated in both hypertension and chronic kidney disease (CKD). Hypertension is a major risk factor for CKD progression. In the present study we have investigated the effects of chronic single tempol (membrane-perme