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Autor:
Oleksandr Maximyuk, Oleg Krishtal, Artur Romanov, D.S. Isaev, Murat Oz, Gregory L. Holmes, O Netsyk, Olha Zapukhliak
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 3, p e0240074 (2021)
PLoS ONE, Vol 16, Iss 3, p e0240074 (2021)
Cholinergic modulation of hippocampal network function is implicated in multiple behavioral and cognitive states. Activation of nicotinic and muscarinic acetylcholine receptors affects neuronal excitability, synaptic transmission and rhythmic oscilla
Autor:
Junhyung Kim, Gi-Hyeok Yang, Jangmi Lee, Seongsung Kwak, Won-ho Kang, Mi-Sun Park, Chang-Hoon Rhee, Woo-Chan Son
Publikováno v:
PLoS ONE, Vol 16, Iss 8, p e0256869 (2021)
PLoS ONE
PLoS ONE
Human serum albumin (HSA) has been widely used as a pharmaceutical excipient in Botulinum toxin serotype A (BoNT/A) products that are indicated for use in therapeutics and cosmetics. However, HSA as a human-derived material has some concerns, such as
Publikováno v:
PLoS ONE, Vol 16, Iss 3, p e0247890 (2021)
PLoS ONE
PLoS ONE
Objective This study aimed to monitor the secretion of serotonin and melatonin in the blood serum of rats in the presence of rice bran (RB), and Sarcodon aspratus (S) extracts for sleep promotion. Background Sleep is a natural physiological phenomeno
Publikováno v:
PLoS ONE, Vol 16, Iss 3, p e0248584 (2021)
PLoS ONE
PLoS ONE
A treatment option for constipation that improves the quality of life is needed since available laxatives do not effectively improve the quality of life in patients with constipation. A significant association between gut dysbiosis and constipation i
Publikováno v:
PLoS ONE, Vol 16, Iss 9, p e0257012 (2021)
PLoS ONE
PLoS ONE
Sodium carboxymethyl starch (CMS-Na), a kind of food additive with high degree of substitution, is also known as a prebiotic. The aim of this study was to determine the effect of CMS-Na on defecation. Constipated mouse model was prepared by loperamid
Autor:
Byung Kook Lee, Najmiddin Mamadjonov, Chun Song Youn, In Seok Jeong, Yong Il Min, Hyoung Youn Lee, Tag Heo, Yong Hun Jung, Kyung Woon Jeung
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 4, p e0249794 (2021)
PLoS ONE, Vol 16, Iss 4, p e0249794 (2021)
Several studies have suggested that sympathetic overstimulation causes deleterious effects in septic shock. A previous study suggested that pralidoxime exerted a pressor effect through a mechanism unrelated to the sympathetic nervous system; this eff
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 3, p e0230238 (2020)
PLoS ONE, Vol 15, Iss 3, p e0230238 (2020)
Social withdrawal in the sub-chronic phencyclidine (PCP) rat model, a behavioral correlate of the negative symptoms of schizophrenia, results from deficits in brain endocannabinoid transmission. As cannabis intake has been shown to affect negatively
Autor:
Alberto Marcos, Mario Moreno, Javier Orihuel, Marcos Ucha, Ana Mª de Paz, Alejandro Higuera-Matas, Roberto Capellán, Antonio L Crego, María-Rosa Martínez-Larrañaga, Emilio Ambrosio, Arturo Anadón
Publikováno v:
PLoS ONE, Vol 15, Iss 3, p e0227044 (2020)
PLoS ONE
PLoS ONE
Under paradigms of combined intravenous cocaine and ethanol self-administration, the effects on behavior have been poorly explored. Numerous studies have found sex differences in amino acids profile and behavioral responses to each drug, yet few have
Publikováno v:
PLoS ONE, Vol 15, Iss 7, p e0236363 (2020)
PLoS ONE
PLoS ONE
Auditory steady-state responses (ASSRs) are states in which the electrical activity of the brain reacts steadily to repeated auditory stimuli. They are known to be useful for testing the functional integrity of neural circuits in the cortex, as well
Autor:
Joanne Tran, Lina Gao, Beth A. Habecker, William R. Woodward, Suzanne S. Fei, Richard Bayles, Antoinette Olivas
Publikováno v:
PLoS ONE
PLoS ONE, Vol 14, Iss 6, p e0218133 (2019)
PLoS ONE, Vol 14, Iss 6, p e0218133 (2019)
The stellate ganglia are the predominant source of sympathetic innervation to the heart. Remodeling of sympathetic nerves projecting to the heart has been observed in several cardiovascular diseases, and sympathetic dysfunction contributes to cardiac