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Autor:
Chiocchetti, Andreas G., Yousaf, Afsheen, Kohls, Gregor, Vetro, Agnes, Hervas, Amaia, Fernández-Rivas, Aranzazu, Freitag, Christine M., Waltes, Regina, Bernhard, Anka, Martinelli, Anne, Ackermann, Katharina, Haslinger, Denise, Rotter, Björn, Krezdorn, Nico, Konrad, Kerstin
Publikováno v:
PLoS ONE, Vol 17, Iss 1, p e0261691 (2022)
PLOS ONE 17(1), e0261691-(2022). doi:10.1371/journal.pone.0261691
PLoS ONE
PLOS ONE 17(1), 1-7 (2022). doi:10.1371/journal.pone.0261691
PLOS ONE 17(1), e0261691-(2022). doi:10.1371/journal.pone.0261691
PLoS ONE
PLOS ONE 17(1), 1-7 (2022). doi:10.1371/journal.pone.0261691
PLOS ONE 17(1), 1-7 (2022). doi:10.1371/journal.pone.0261691
Published by PLOS, San Francisco, California, US
Published by PLOS, San Francisco, California, US
Autor:
Christel Rousseaux, Paolo Spagnolo, Silvia Speca, Caroline Dubuquoy, Pierre Desreumaux, Philippe Chavatte
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 9, p e0257281 (2021)
PLoS ONE, Vol 16, Iss 9, p e0257281 (2021)
The development of more effective, better tolerated drug treatments for progressive pulmonary fibrosis (of which idiopathic pulmonary fibrosis is the most common and severe form) is a research priority. The peroxisome proliferator-activated receptor
Autor:
Katharine L. Korunes, Jie Liu, Ruili Huang, Menghang Xia, Keith A. Houck, J. Christopher Corton
Publikováno v:
PLoS ONE
PLoS ONE, Vol 17, Iss 2, p e0261854 (2022)
PLoS ONE, Vol 17, Iss 2, p e0261854 (2022)
The nuclear factor-kappa B (NF-κB) is a transcription factor with important roles in inflammation, immune response, and oncogenesis. Dysregulation of NF-κB signaling is associated with inflammation and certain cancers. We developed a gene expressio
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 11 (2021)
PLoS ONE, Vol 16, Iss 11, p e0260071 (2021)
PLoS ONE, Vol 16, Iss 11 (2021)
PLoS ONE, Vol 16, Iss 11, p e0260071 (2021)
Hyperglycemia is generally considered to be an important cause of diabetic retinopathy (DR). The aim of the present study was to investigate the role of miR-5195-3p in high glucose (HG)-induced human retinal pigment epithelial ARPE-19 cell injury. He
Autor:
Yumi Maeda, Yuqian Luo, Kazuaki Yokoyama, Koichi Suzuki, Yasuhiro Nakamura, Ken Karasawa, Akira Kawashima, Mitsuo Kiriya, Kotaro Hama, Atsushi Yamashita, Yasuhiro Hayashi, Kazunari Tanigawa, Ayako Harada
Publikováno v:
PLoS ONE, Vol 16, Iss 3, p e0249184 (2021)
PLoS ONE
PLoS ONE
Mycobacterium leprae (M. leprae) is the etiological agent of leprosy, and the skin lesions of lepromatous leprosy are filled with numerous foamy or xanthomatous histiocytes that are parasitized by M. leprae. Lipids are an important nutrient for the i
Autor:
Jialu Qiao, Qian Peng, Feng Qian, Qiang You, Lingyan Feng, Song Hu, Wei Liu, Lixia Huang, Xiji Shu, Binlian Sun
Publikováno v:
PLoS ONE, Vol 16, Iss 12, p e0261971 (2021)
PLoS ONE
PLoS ONE
MicroRNAs (miRNAs) are important molecules that mediate virus-host interactions, mainly by regulating gene expression via gene silencing. Here, we demonstrated that HIV-1 infection upregulated miR-210-5p in HIV-1-inoculated cell lines and in the seru
Autor:
Masaki Nishimura, Takao Morimune, Haruka Yukiue, Yoshihiro Maruo, Yuya Tanaka, Takefumi Yamamoto, Masaki Mori, Ayami Tano, Ikuo Tooyama
Publikováno v:
PLoS ONE, Vol 16, Iss 4, p e0248517 (2021)
PLoS ONE
PLoS ONE
It is not fully understood how enzymes are regulated in the tiny reaction field of a cell. Several enzymatic proteins form cytoophidia, a cellular macrostructure to titrate enzymatic activities. Here, we show that the epileptic encephalopathy-associa
Publikováno v:
PLoS ONE, Vol 16, Iss 6, p e0253821 (2021)
PLoS ONE
PLoS ONE
Recently, we reported that the chemokine (C-X-C motif) receptor 4 (CXCR4) and atypical chemokine receptor 3 (ACKR3) heteromerize with α1A/B/D-adrenoceptors (ARs) and arginine vasopressin receptor 1A (AVPR1A) in recombinant systems and in rodent and
Publikováno v:
PLoS ONE, Vol 16, Iss 11, p e0259894 (2021)
PLoS ONE, Vol 16, Iss 11 (2021)
PLoS ONE
PLoS ONE, Vol 16, Iss 11 (2021)
PLoS ONE
Neutrophil extracellular traps (NETs) are web-like structures, which are released upon neutrophil activation. It has previously been demonstrated that NETs are present in atherosclerotic lesions of both humans and animal models thus playing a decisiv
Autor:
Marat S. Pavlyukov, L. I. Patrushev, Mikhail I. Shakhparonov, Alina M. Gamisoniya, Ksenia Anufrieva, Ksenia V. Morozova, T. F. Kovalenko, Lyudmila A. Ozolinya, Mikhail Yu. Bobrov, Yulia E. Dobrokhotova
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 1, p e0243093 (2021)
PLoS ONE, Vol 16, Iss 1, p e0243093 (2021)
The processed pseudogene PTENP1 is involved in the regulation of the expression of the PTEN and acts as a tumor suppressor in many types of malignances. In our previous study we showed that PTENP1 methylation is present not only in tumor, but also in