Zobrazeno 101 - 110
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pro vyhledávání: ''
Autor:
Elena H. Chartoff, Marco Pravetoni, David N. Potter, Mark G. LeSage, Paul R. Pentel, Laura Tally
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e101807 (2014)
PLoS ONE
PLoS ONE
Prescription opioid abuse is an increasing public health concern in the USA. A vaccine comprising a hapten (OXY) conjugated to the carrier protein keyhole limpet hemocyanin (OXY-KLH) has been shown to attenuate the antinociceptive effects of oxycodon
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e98681 (2014)
PLoS ONE
PLoS ONE
We recently reported that chronic nicotine impairs reflex chronotropic activity in female rats. Here, we sought evidence to implicate nitric oxide synthase (NOS) and/or heme oxygenase (HO) in the nicotine-baroreflex interaction. Baroreflex curves rel
Autor:
Yukihiro Wada, Taihei Suzuki, Ken Iseri, Masayuki Iyoda, Tomohiro Saito, Takanori Shibata, Yoshihiro Kuno, Yuki Shindo-Hirai, Yasutaka Yamamoto, Kei Matsumoto
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e111728 (2014)
PLoS ONE
PLoS ONE
The effects of blocking the epidermal growth factor receptor (EGFR) in acute kidney injury (AKI) are controversial. Here we investigated the renoprotective effect of erlotinib, a selective tyrosine kinase inhibitor that can block EGFR activity, on ci
Autor:
María Claudia, Sandoval-Usme, Adriana, Umaña-Pérez, Borja, Guerra, Octavio, Hernández-Perera, Orlando, Hernández-Perera, José Manuel, García-Castellano, Leandro, Fernández-Pérez, Myriam, Sánchez-Gómez
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e87769 (2014)
Digital.CSIC. Repositorio Institucional del CSIC
instname
PLoS ONE
Digital.CSIC. Repositorio Institucional del CSIC
instname
PLoS ONE
This is an open-access article distributed under the terms of the Creative Commons Attribution License.-- et al.
Recent studies have demonstrated that statins reduce cell viability and induce apoptosis in various types of cancer cells. The molec
Recent studies have demonstrated that statins reduce cell viability and induce apoptosis in various types of cancer cells. The molec
Autor:
José Heriberto Oliveira do Nascimento, Raimundo Fernandes de Araújo Júnior, Gerly Anne de Castro Brito, Hugo de Almeida Varela, Aurigena Antunes de Araújo, Lorena de Souza Araújo, Caroline Addison Carvalho Xavier de Medeiros
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e96750 (2014)
PLoS ONE
Repositório Institucional da Universidade Federal do Ceará (UFC)
Universidade Federal do Ceará (UFC)
instacron:UFC
Repositório Institucional da UFRN
Universidade Federal do Rio Grande do Norte (UFRN)
instacron:UFRN
PLoS ONE
Repositório Institucional da Universidade Federal do Ceará (UFC)
Universidade Federal do Ceará (UFC)
instacron:UFC
Repositório Institucional da UFRN
Universidade Federal do Rio Grande do Norte (UFRN)
instacron:UFRN
AimsThe aim of this study was to evaluate the effects of azilsartan (AZT) on bone loss, inflammation, and the expression of matrix metallo proteinases (MMPs), receptor activator of nuclear factor κB ligand (RANKL), receptor activator of nuclear fact
Autor:
Pouya Hassandarvish, Nahla Saeed Al-Wajeeh, Maryam Hajrezaie, Abdulwali Ablat, Anwar Norazit, Raied Mustafa Shakir, Daleya Abdulaziz Bardi, Mahmood Ameen Abdulla, Mohammed Farouq Halabi
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e95908 (2014)
PLoS ONE
PLoS ONE
Background The study was carried out to determine the cytotoxic, antioxidant and gastro-protective effect of ethyl-4-[(3,5-di-tert-butyl-2-hydroxybenzylidene)amino] benzoate (ETHAB) in rats. Methodology/Principal Findings The cytotoxic effect of E
Autor:
Anil Kumar Kalvala, Shyam Sunder Rachamalla, Ramakrishna Sistla, Bidya Dhar Sahu, Meghana Koneru, Jerald Mahesh Kumar, Madhusudana Kuncha
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e105070 (2014)
PLoS ONE
PLoS ONE
Nephrotoxicity is a dose-dependent side effect of cisplatin limiting its clinical usage in the field of cancer chemotherapy. Fisetin is a bioactive flavonoid with recognized antioxidant and anti-inflammatory properties. In the present study, we inves
Autor:
Ming-Xiang Zhang, Xiangjuan Liu, Fengshuang An, Yanfei Xia, Yun Zhang, Cheng Zhang, Wen-ke Wang, Beibei Luo, Bo Li
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e104771 (2014)
PLoS ONE
PLoS ONE
Background Nucleotide-binding oligomerization domain-like receptor protein 3 (NLRP3) inflammasome is associated with metabolic disorder and cell death, which are important triggers in diabetic cardiomyopathy (DCM). We aimed to explore whether NLRP3 i
Autor:
Roland Andersson, Bicheng Chen, Mengtao Zhou, Hongwei Sun, Yangyun Xie, Weiming Wang, Jianming Xie, Yuepeng Jin, Dan Xu, Fajing Yang
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e108525 (2014)
PLoS ONE; 9(9), no e108525 (2014)
PLoS ONE
PLoS ONE; 9(9), no e108525 (2014)
PLoS ONE
Objective Investigate the therapeutic effect of regional arterial infusion (RAI) with Aspirin-Triggered Lipoxin A4 (ATL) in experimental severe acute pancreatitis (SAP) in rats. Materials and Methods SAP was induced by injection of 5% sodium taurocho
Autor:
Lu Jin, Lu-Lu Pan, Jing-jing Min, Cui-cui Zhao, Xin-long Huo, Cai-yu Pan, Fei-fei Gui, Xiaotong Wang
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e94278 (2014)
PLoS ONE
PLoS ONE
BackgroundChronic intermittent hypoxia-hypercapnia (CIHH) exposure leads to learnning and memory deficits in rats. Overactivation of N-methyl-D-aspartate receptors(NMDARs) can lead to the death of neurons through a process termed excitotoxicity, whic