Zobrazeno 1 - 10
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pro vyhledávání: ''
Autor:
Victor E. Arana-Chavez, Alyne Simões, Cíntia Yuki Fukuoka, Hugo Passos Vicari, Ujjal K. Bhawal, Carla Renata Sipert, Yoshimitsu Abiko
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 8, p e0236727 (2020)
PLoS ONE, Vol 15, Iss 8, p e0236727 (2020)
Low-power laser irradiation (LPLI) is clinically used to modulate inflammation, proliferation and apoptosis. However, its molecular mechanisms are still not fully understood. This study aimed to describe the effects of LPLI upon inflammatory, apoptot
Autor:
Shohreh Issazadeh-Navikas, Michal K. Oklinski, Tae-Hwan Kwon, Angelique Corthals, Robert Bockermann, Agnete Larsen, Søren Nielsen, Anne Skøttrup Mørkholt, John Nieland, Jette G. K. Nieland
Publikováno v:
Mørkholt, A S, Oklinski, M K, Larsen, A, Bockermann, R, Issazadeh-Navikas, S, Nieland, J G K, Kwon, T-H, Corthals, A, Nielsen, S & Nieland, J D V 2020, ' Pharmacological inhibition of carnitine palmitoyl transferase 1 inhibits and reverses experimental autoimmune encephalitis in rodents ', PLoS ONE, vol. 15, no. 6, pp. e0234493 . https://doi.org/10.1371/journal.pone.0234493
PLoS ONE
Mørkholt, A S, Oklinski, M K, Larsen, A, Bockermann, R, Issazadeh-Navikas, S, Nieland, J G K, Kwon, T-H, Corthals, A, Nielsen, S & Nieland, J D V 2020, ' Pharmacological inhibition of carnitine palmitoyl transferase 1 inhibits and reverses experimental autoimmune encephalitis in rodents ', PLOS ONE, vol. 15, no. 6, e0234493 . https://doi.org/10.1371/journal.pone.0234493
PLoS ONE, Vol 15, Iss 6, p e0234493 (2020)
Mørkholt, A S, Oklinski, M K, Larsen, A, Bockermann, R, Issazadeh-Navikas, S, Nieland, J G K, Kwon, T H, Corthals, A, Nielsen, S & Nieland, J D V 2020, ' Pharmacological inhibition of carnitine palmitoyl transferase 1 inhibits and reverses experimental autoimmune encephalitis in rodents ', PLOS ONE, vol. 15, no. 6, e0234493 . https://doi.org/10.1371/journal.pone.0234493
PLoS ONE
Mørkholt, A S, Oklinski, M K, Larsen, A, Bockermann, R, Issazadeh-Navikas, S, Nieland, J G K, Kwon, T-H, Corthals, A, Nielsen, S & Nieland, J D V 2020, ' Pharmacological inhibition of carnitine palmitoyl transferase 1 inhibits and reverses experimental autoimmune encephalitis in rodents ', PLOS ONE, vol. 15, no. 6, e0234493 . https://doi.org/10.1371/journal.pone.0234493
PLoS ONE, Vol 15, Iss 6, p e0234493 (2020)
Mørkholt, A S, Oklinski, M K, Larsen, A, Bockermann, R, Issazadeh-Navikas, S, Nieland, J G K, Kwon, T H, Corthals, A, Nielsen, S & Nieland, J D V 2020, ' Pharmacological inhibition of carnitine palmitoyl transferase 1 inhibits and reverses experimental autoimmune encephalitis in rodents ', PLOS ONE, vol. 15, no. 6, e0234493 . https://doi.org/10.1371/journal.pone.0234493
Multiple sclerosis (MS) is a neurodegenerative disease characterized by demyelination and inflammation. Dysregulated lipid metabolism and mitochondrial dysfunction are hypothesized to play a key role in MS. Carnitine Palmitoyl Transferase 1 (CPT1) is
Autor:
Steven H.K. Chung, Raymond M.H. Wong, Yu On Leung, Yijun Cai, Oscar M. Leung, Alan W.L. Law, Sui Yi Kwok, Ka Chun Chau, Yun Chung Leung, Jeremy P.H. Chow, Daniel T.L. Chow, Ka Ying Ng
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 4, p e0231633 (2020)
PLoS ONE, Vol 15, Iss 4, p e0231633 (2020)
Arginine deprivation cancer therapy targets certain types of malignancies with positive result in many studies and clinical trials. NEI-01 was designed as a novel arginine-depleting enzyme comprising an albumin binding domain capable of binding to hu
Autor:
Kristen C. Hunn, Leigh M. Jacobs, Tally M. Largent-Milnes, Chelsea Jarvis, Nathan B. Arkwright, Thomas P. Davis, Margaret E. Tome, Charles P. Schaefer
Publikováno v:
PLoS ONE
PLoS ONE, Vol 13, Iss 2, p e0192340 (2018)
PLoS ONE, Vol 13, Iss 2, p e0192340 (2018)
The rates of opioid prescription and use have continued to increase over the last few decades resulting in a greater number of opioid tolerant patients. Treatment of acute pain from surgery and injury is a clinical challenge for these patients. Sever
Autor:
Thiago Berti Kirsten, Maria Martha Bernardi, Luciano Freitas Felício, Renato Corrêa Viana Casarin
Publikováno v:
PLoS ONE, Vol 13, Iss 5, p e0197060 (2018)
PLoS ONE
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
PLoS ONE
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Autism is characterized by social deficits, communication abnormalities, and repetitive behaviors. The risk factors appear to include genetic and environmental conditions, such as prenatal infections and maternal dietary factors. Previous investigati
Publikováno v:
PLoS ONE, Vol 13, Iss 10, p e0205372 (2018)
PLoS ONE
PLoS ONE
Development and maturation of submandibular salivary glands are influenced by intrauterine diabetic environment. Several studies investigated the effects of diabetes on the salivary glands. However, the effects of maternal diabetes on the submandibul
Autor:
Christoph Bührer, Claudia Spies, Stefanie Endesfelder, Marco Sifringer, Clarissa von Haefen, Hanan Makki
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0171498 (2017)
PLoS ONE
PLoS ONE
Dexmedetomidine (DEX) is a highly selective agonist of α2-receptors with sedative, anxiolytic, and analgesic properties. Neuroprotective effects of dexmedetomidine have been reported in various brain injury models. In the present study, we investiga
Autor:
Nabanita Halder, Rajvardhan Azad, Madhu Nath, Thirumurthy Velpandian, Baskar Singh, Ashok K. Deorari, Atul Kumar, Parijat Chandra
Publikováno v:
PLoS ONE
PLoS ONE, Vol 11, Iss 12, p e0168809 (2016)
PLoS ONE, Vol 11, Iss 12, p e0168809 (2016)
Objective Examining the Retinal Renin Angiotensin System (RRAS) in the ROP neonates and analyzing the possibility of modulating the RRAS to prevent the progression in Oxygen Induced Retinopathy (OIR) model. Method Vitreous of ROP patients (n = 44, me
Autor:
Yunlin Feng, Qi Yu, Zhiyi Liu, Jiamei Lin, Liuqin Wu, Zhiyi Zuo, Yan Hu, Lin Xu, Weilu Zhao, Binda Li, Foquan Luo
Publikováno v:
PLoS ONE, Vol 11, Iss 8, p e0160826 (2016)
PLoS ONE
PLoS ONE
Increasing evidence indicates that most general anesthetics can harm developing neurons and induce cognitive dysfunction in a dose- and time-dependent manner. Histone deacetylase 2 (HDAC2) has been implicated in synaptic plasticity and learning and m
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0164796 (2016)
PLoS ONE
PLoS ONE
Urine, reflecting many changes in the body, is a better source than blood for biomarker discovery. However, even under physiological conditions, the urine proteome often varies. Understanding how various regulating factors affect urine proteome helps