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Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 6, p e0253731 (2021)
PLoS ONE, Vol 16, Iss 6, p e0253731 (2021)
This study aimed to evaluate the effects of epidural anaesthesia with lidocaine in combination with general anaesthesia with propofol on some immunologic indices in dogs undergoing ovariohysterectomy. Twelve adult dogs were anesthetized with propofol
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 2, p e0246213 (2021)
PLoS ONE, Vol 16, Iss 2, p e0246213 (2021)
Despite the need for safe and effective postoperative analgesia in neonates, research regarding pain management in neonatal rodents is relatively limited. Here, we investigate whether sustained release buprenorphine (Bup SR) effectively attenuates th
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 1, p e0244244 (2021)
PLoS ONE, Vol 16, Iss 1, p e0244244 (2021)
Dietary interventions such as intermittent fasting and the ketogenic diet have demonstrated neuroprotective effects in various models of neurological insult. However, there has been a lack of evaluation of these interventions from a surgical perspect
Publikováno v:
PLoS ONE, Vol 16, Iss 1, p e0245553 (2021)
PLoS ONE
PLoS ONE
ObjectiveTo evaluate the effect of an intra-articular (IA) administration of triamcinolone hexacetonide, compared with saline.Patients and methodsForty (N = 40) hip joints were randomly assigned to a treatment group (THG, n = 20, receiving IA triamci
Publikováno v:
PLoS ONE, Vol 16, Iss 7, p e0254497 (2021)
PLoS ONE
PLoS ONE
The aim of the study was to evaluate the analgesic efficacy of tramadol compared to butorphanol administered locally in ventral surface of the hind paw of rats. Prospective, randomized experimental study; twenty-one adult male Wistar rats were select
Autor:
Maria do Socorro de Sousa Cartágenes, José Osvaldo Barbosa Neto, João Batista Santos Garcia, Lyvia Maria Rodrigues de Sousa Gomes, Rayanne Luiza Tajra Mualem Araújo, Nicolau Gregori Czeczko
Publikováno v:
PLoS ONE, Vol 16, Iss 1, p e0245194 (2021)
PLoS ONE
PLoS ONE
Pharmacological treatment of osteoarthritis is still inadequate due to the low efficacy of the drugs used. Dexmedetomidine via the intra-articular (i.a.) route might be an option for the treatment of osteoarthritis-associated pain. The present study
Publikováno v:
PLoS ONE, Vol 16, Iss 8, p e0255155 (2021)
PLoS ONE
PLoS ONE, Vol 16, Iss 8 (2021)
PLoS ONE
PLoS ONE, Vol 16, Iss 8 (2021)
Use of normothermic ex vivo lung perfusion (EVLP) was adopted in clinical practice to assess the quality of marginal donor lungs. Subnormothermic perfusion temperatures are in use among other solid organs to improve biochemical, clinical and immunolo
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 6, p e0235046 (2020)
PLoS ONE, Vol 15, Iss 6, p e0235046 (2020)
Post-ictal emergence of slow wave EEG (electroencephalogram) activity and burst-suppression has been associated with the therapeutic effects of the electroconvulsive therapy (ECT), indicating that mere “cerebral silence” may elicit antidepressant
Publikováno v:
PLoS ONE, Vol 15, Iss 4, p e0231090 (2020)
PLoS ONE
PLoS ONE
Sevoflurane and isoflurane are among the most commonly used general anesthetics for children including infants, but their impact on metabolism, especially on blood glucose level, in children is not well understood. We investigated the impacts of anes
Autor:
Maik Brune, B. Luise Deutsch, Armin Kalenka, Alexander Harms, M. O. Fiedler, Markus A. Weigand, Florian Uhle, Emilis Simeliunas, Thorsten Brenner, Dovile Diktanaite
Publikováno v:
PLoS ONE, Vol 15, Iss 4, p e0230830 (2020)
PLoS ONE
PLoS ONE
INTRODUCTION Intra-abdominal hypertension (IAH) is a well-known phenomenon in critically ill patients. Effects of a moderately elevated intra-abdominal pressure (IAP) on lung mechanics are still not fully analyzed. Moreover, the optimal positive end-