Zobrazeno 1 - 10
of 90
pro vyhledávání: ''
Autor:
Kyoung Min Moon, Mi Jung Kwon, Young Wha Koh, Il Hwan Oh, Intazur Rahaman, Eun Kyung Kim, Kyueng-Whan Min, So Myoung Kim, So Won Kim, Byoung Kwan Son, Dong-Hoon Kim
Publikováno v:
PLoS ONE, Vol 16, Iss 3, p e0245075 (2021)
PLoS ONE
PLoS ONE
High expression of glucose transporter family members, which augment glucose uptake and glycolytic flux, has been shown to play a pivotal role in the proliferation and survival of tumor cells, contributing to the energy supply, biosynthesis and homeo
Autor:
Piet Pattyn, Charlotte Vandeputte, Lieven Depypere, Bram De Laere, Philippe Nafteux, Katleen De Preter, Steffi Oeyen, Annouck Philippron
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 5, p e0251052 (2021)
PLOS ONE
PLoS ONE, Vol 16, Iss 5, p e0251052 (2021)
PLOS ONE
Objective The enrichment of circulating tumor cells (CTCs) from blood provides a minimally invasive method for biomarker discovery in cancer. Longitudinal interrogation allows monitoring or prediction of therapy response, detection of minimal residua
Autor:
Mikiya Fujii, Kosuke Ogawa, Atsushi Kudo, Toshiro Ogura, Shinji Tanaka, Daisuke Ban, Hiroaki Ono, Tomotaka Kato, Minoru Tanabe, Keiichi Akahoshi
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 6 (2021)
PLoS ONE, Vol 16, Iss 6, p e0252917 (2021)
PLoS ONE, Vol 16, Iss 6 (2021)
PLoS ONE, Vol 16, Iss 6, p e0252917 (2021)
BackgroundRRM1 is functionally associated with DNA replication and DNA damage repair. However, the biological activity of RRM1 in pancreatic cancer remains undetermined.MethodsTo determine relationships between RRM1 expression and the prognosis of pa
Autor:
Akinobu Taketomi, Moto Fukai, Hideki Yokoo, Toshiya Kamiyama, Kanako C. Hatanaka, Takeshi Aiyama, Yutaka Hatanaka, Tatsuya Orimo, Takanori Ohata
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 9, p e0239462 (2020)
PLoS ONE, Vol 15, Iss 9, p e0239462 (2020)
This study was performed to determine the clinical significance of adenomatous polyposis coli (APC)-binding protein end-binding 1 (EB1) in hepatocellular carcinoma (HCC) and to characterize its biochemical role in comparison with previous reports. We
Autor:
J.M. Galbis, Javier Alcácer, José Javier Martín de Llano, María Oliver, Carmen Carda, Manuel de la Mata, María Sancho-Tello, Julian Carretero, Lara Milian, Carlos Camps
Publikováno v:
PLoS ONE
PLoS One
r-FISABIO: Repositorio Institucional de Producción Científica
Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO)
r-FISABIO. Repositorio Institucional de Producción Científica
instname
PLoS ONE, Vol 15, Iss 2, p e0228909 (2020)
r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVA
PLoS One
r-FISABIO: Repositorio Institucional de Producción Científica
Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO)
r-FISABIO. Repositorio Institucional de Producción Científica
instname
PLoS ONE, Vol 15, Iss 2, p e0228909 (2020)
r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVA
Background/Objective Patients with non-small cell lung cancer (NSCLC) develop resistance to antitumor agents by mechanisms that involve the epithelial-to-mesenchymal transition (EMT). This necessitates the development of new complementary drugs, e.g.
Autor:
Yusuke Tsuruda, Taro Tobo, Yosuke Kuroda, Shotaro Kuramitsu, Koshi Mimori, Shinya Kidogami, Qingjiang Hu, Masaki Mori, Shuhei Ito, Takaaki Masuda, Sho Nambara, Eiji Oki, Masami Ueda, Kuniaki Sato
Publikováno v:
PLoS ONE, Vol 15, Iss 10, p e0241140 (2020)
PLoS ONE
PLoS ONE
BackgroundPeritoneal dissemination (PD) frequently occurs in gastric cancer (GC) and is incurable. In this study, we aimed to identify novel PD-associated genes and clarify their clinical and biological significance in GC.Materials and methodsWe iden
Autor:
Debu Tripathy, Naoto T. Ueno, Kumiko Kida, Darren W. Davis, Diane D. Liu, James M. Reuben, Carlos H. Barcenas, Takeo Fujii, Minjeong Park, Vicente Valero, Mariana Chavez-MacGregor, Fanny Le Du, Weiguo Wu
Publikováno v:
PLoS ONE, Vol 15, Iss 3, p e0229903 (2020)
PLoS ONE
PLoS ONE
BackgroundTumor cells with a mesenchymal phenotype and/or cancer stem-like cells (CSCs) are known to contribute to metastasis and drug resistance. Circulating tumor cells (CTCs) undergoing epithelial-mesenchymal transition (EMT) and CTCs reflecting a
Autor:
Gunhild Mari Mælandsmo, Marta Nyakas, Erin McFadden, Patrik Wernhoff, Kari Dolven Jacobsen, Karine Flem-Karlsen, I. N. Farstad, Vivi Ann Flørenes
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 1, p e0227187 (2020)
PLoS ONE, Vol 15, Iss 1, p e0227187 (2020)
Receptor tyrosine kinase AXL is a one-pass transmembrane protein upregulated in cancers and associated with lower survival and therapy resistance. AXL can be cleaved by the A Disintegrin and Metalloproteinases (ADAM)10 and ADAM17, yielding a soluble
Autor:
Rakesh K. Tyagi, Sudhir Rawal, Gunjan Dagar, Ravi Datta Sharma, Julie Pratibha Singh, Sudhir Kumar, Gargi Bagchi, Manisha Dagar
Publikováno v:
PLoS ONE, Vol 15, Iss 9, p e0226056 (2020)
PLoS ONE
PLoS ONE
The androgen receptor (AR) is activated in patients with castration resistant prostate cancer (CRPC) despite low circulating levels of androgen, suggesting that intracellular signaling pathways and non-androgenic factors may contribute to AR activati
Autor:
Carmen Ili, Kurt Buchegger, Priscilla Brebi, Stephen R. Piccolo, Ismael Riquelme, Louise Zanella, María Elena Reyes, Alyssa C. Parker, Irene Cartas-Espinel, Tamara Viscarra, Barbara Mora-Lagos
Publikováno v:
PLoS ONE, Vol 15, Iss 1, p e0228331 (2020)
PLoS ONE
PLoS ONE
Gastric cancer (GC) is a significant cancer-related cause of death worldwide. The most used chemotherapeutic regimen in GC is based on platinum drugs such as cisplatin (CDDP). However, CDDP resistance reduces advanced GC survival. In vitro drug-resis