Zobrazeno 131 - 140
of 192
pro vyhledávání: '"398"'
Autor:
Dharambir K Sanghera, Latonya F Been, Sarju Ralhan, Gurpreet S Wander, Narinder K Mehra, Jai Rup Singh, Robert E Ferrell, Mohammed I Kamboh, Christopher E Aston
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e21188 (2011)
In this investigation, we have carried out an autosomal genome-wide linkage analysis to map genes associated with type 2 diabetes (T2D) and five quantitative traits of blood lipids including total cholesterol, high-density lipoprotein (HDL) cholester
Externí odkaz:
https://doaj.org/article/0b30c41060f7488688aaf1e7fe4eee1b
Autor:
Christine A M Payan, François Viallet, Bernhard G Landwehrmeyer, Anne-Marie Bonnet, Michel Borg, Franck Durif, Lucette Lacomblez, Frédéric Bloch, Marc Verny, Jacques Fermanian, Yves Agid, Albert C Ludolph, Peter N Leigh, Gilbert Bensimon, NNIPPS Study Group
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e22293 (2011)
The Natural History and Neuroprotection in Parkinson Plus Syndromes (NNIPPS) study was a large phase III randomized placebo-controlled trial of riluzole in Progressive Supranuclear Palsy (PSP, n = 362) and Multiple System Atrophy (MSA, n = 398). To a
Externí odkaz:
https://doaj.org/article/a2e443fa8eef46ee84896ee858169e23
Autor:
Ravi Kalhan, Betty T Tran, Laura A Colangelo, Sharon R Rosenberg, Kiang Liu, Bharat Thyagarajan, David R Jacobs, Lewis J Smith
Publikováno v:
PLoS ONE, Vol 5, Iss 7, p e11431 (2010)
BACKGROUND:Systemic inflammation is associated with reduced lung function in both healthy individuals and those with chronic obstructive pulmonary disease (COPD). Whether systemic inflammation in healthy young adults is associated with future impairm
Externí odkaz:
https://doaj.org/article/301b45cbf9774c4f808a0a0ea29c523c
Autor:
Kylie L Gorringe, Joshy George, Michael S Anglesio, Manasa Ramakrishna, Dariush Etemadmoghadam, Prue Cowin, Anita Sridhar, Louise H Williams, Samantha E Boyle, Nozomu Yanaihara, Aikou Okamoto, Mitsuyoshi Urashima, Gordon K Smyth, Ian G Campbell, David D L Bowtell, Australian Ovarian Cancer Study
Publikováno v:
PLoS ONE, Vol 5, Iss 9, p e815 (2010)
Ovarian cancer is a heterogeneous disease displaying complex genomic alterations, and consequently, it has been difficult to determine the most relevant copy number alterations with the scale of studies to date. We obtained genome-wide copy number al
Externí odkaz:
https://doaj.org/article/bf27f078765340e890a95da9aab9f420
Autor:
Sanjay Chandriani, Eirik Frengen, Victoria H Cowling, Sarah A Pendergrass, Charles M Perou, Michael L Whitfield, Michael D Cole
Publikováno v:
PLoS ONE, Vol 4, Iss 8, p e6693 (2009)
BACKGROUND:The MYC oncogene contributes to induction and growth of many cancers but the full spectrum of the MYC transcriptional response remains unclear. METHODOLOGY/PRINCIPAL FINDINGS:Using microarrays, we conducted a detailed kinetic study of gene
Externí odkaz:
https://doaj.org/article/69ff29d0c9f247e09bbe3c302719b746
Publikováno v:
PLoS ONE, Vol 4, Iss 5, p e5542 (2009)
DRIL1 is an ARID family transcription factor that can immortalize primary mouse fibroblasts, bypass RAS(V12)-induced cellular senescence and collaborate with RAS(V12) or MYC in mediating oncogenic transformation. It also activates immunoglobulin heav
Externí odkaz:
https://doaj.org/article/b6173a6219ab49f0820dd9f6d86a6062
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 7, p e0251708 (2021)
PLoS ONE, Vol 16, Iss 7, p e0251708 (2021)
Background COVID-19 is an emerging infectious disease which is a major public health problem worldwide. Given the serious threats imposed by COVID-19 and the absence of vaccines until August 2020, preventive measures play an essential role in reducin
Publikováno v:
PLoS ONE, Vol 16, Iss 3, p e0249243 (2021)
PLoS ONE
PLoS ONE
Background and objectives Diagnosis of Pulmonary Rifampicin Resistant Tuberculosis (RR-TB) with the Drug-Susceptibility Test (DST) is costly and time-consuming. Furthermore, GeneXpert for rapid diagnosis is not widely available in Indonesia. This stu
Autor:
Chevallier, M. (Marie), Ancel, P-Y. (Pierre-Yves), Torchin, H. (Heloise), Marchand-Martin, L. (Laetitia), Lorthe, E. (Elsa), Truffert, P. (Patrick), Jarreau, P-H. (Pierre-Henri), Roze, J-C. (Jean-Christophe), Pierrat, V. (Véronique), Marret, S. (Stéphane), Baud, O. (Olivier), Benhammou, V. (Valérie), Ego, A. (Anne), Debillon, T. (Thierry)
Publikováno v:
PLoS ONE, Vol 14, Iss 4, p e0214232 (2019)
PLOS ONE, Vol. 14, No 4 (2019) P. e0214232
PLoS ONE
PLoS ONE, Public Library of Science, 2019, 14 (4), pp.e0214232. ⟨10.1371/journal.pone.0214232⟩
PLoS ONE, 2019, 14 (4), pp.e0214232. ⟨10.1371/journal.pone.0214232⟩
PLOS ONE, Vol. 14, No 4 (2019) P. e0214232
PLoS ONE
PLoS ONE, Public Library of Science, 2019, 14 (4), pp.e0214232. ⟨10.1371/journal.pone.0214232⟩
PLoS ONE, 2019, 14 (4), pp.e0214232. ⟨10.1371/journal.pone.0214232⟩
ObjectiveTo determine whether there is an association between severe intraventricular hemorrhage and early extubation in preterm infants born before 29 weeks of gestational age and intubated at birth.MethodsThis study included 1587 preterm infants fr
Publikováno v:
PLoS ONE, Vol 15, Iss 12, p e0244869 (2020)
PLoS ONE
PLoS ONE
Background The diagnosis of gastric cancer mainly relies on endoscopy, which is invasive and costly. The aim of this study is to develop a predictive model for the diagnosis of gastric cancer based on noninvasive characteristics. Aims To construct a