Zobrazeno 1 - 10
of 12
pro vyhledávání: '"785"'
A trichostatin A expression signature identified by TempO-Seq targeted whole transcriptome profiling
Autor:
Peter J. Shepard, Bruce Seligmann, Diana E. Goyena, Harper C. VanSteenhouse, Joel Mccomb, Joanne M. Yeakley
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 5, p e0178302 (2017)
PLoS ONE, Vol 12, Iss 5, p e0178302 (2017)
The use of gene expression signatures to classify compounds, identify efficacy or toxicity, and differentiate close analogs relies on the sensitivity of the method to identify modulated genes. We used a novel ligation-based targeted whole transcripto
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e106706 (2014)
PLoS ONE
PLoS ONE
During folliculogenesis, cumulus cells surrounding the oocyte differentiate into corona radiata cells (CRCs) and cumulus oophorus cells (COCs), which are involved in gonadal steroidogenesis and the development of germ cells. Several studies suggested
Autor:
Richard W. Troughton, Gillian A. Whalley, A. Mark Richards, Vicky A. Cameron, Michael Lever, Timothy G. Yandle, Peter M. George, Robert N. Doughty, Stephen T. Chambers, Anna P. Pilbrow, Lorraine Skelton, Chris Frampton, Katrina L. Ellis, Barry R. Palmer, Sandy Slow, Chris Ellis, Suetonia C. Palmer
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e89029 (2014)
PLoS ONE
PLoS ONE
BACKGROUND AND AIMS: The methylene-tetrahydrofolate dehydrogenase (NADP+ dependent) 1-like (MTHFD1L) gene is involved in mitochondrial tetrahydrofolate metabolism. Polymorphisms in MTHFD1L, including rs6922269, have been implicated in risk for corona
Autor:
Mala Singh, Anish M. Shah, Mohmmad Shoab Mansuri, Nishtha Agarwal, Rasheedunnisa Begum, Naresh C. Laddha, Mitesh Dwivedi, Hetanshi H. Patel
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e107020 (2014)
PLoS ONE
PLoS ONE
Background Vitiligo is a depigmenting disorder resulting from loss of functional melanocytes in the skin. NPY plays an important role in induction of immune response by acting on a variety of immune cells. NPY synthesis and release is governed by IL1
Autor:
Messias Gonzaga Pereira, Newton Medeiros Vidal, Ana Laura Grazziotin, Helaine Christine Cancela Ramos, Thiago M. Venancio
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e112654 (2014)
PLoS ONE
PLoS ONE
Carica papaya (papaya) is an economically important tropical fruit. Molecular marker-assisted selection is an inexpensive and reliable tool that has been widely used to improve fruit quality traits and resistance against diseases. In the present stud
Autor:
Zhijiang Fan, Li Ding, Jing Wang, Ying Shi, Feng Li, Qi Ding, Bo Fan, Wenjian Tu, Xiaohua Jin
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e57246 (2013)
PLoS ONE
PLoS ONE
Interleukin-10 (IL-10) is a multifunctional cytokine which participates in the development and progression of various malignant tumors. To date, a number of case–control studies were conducted to detect the association between IL-10-592C>A polymorp
Publikováno v:
PLoS ONE
PLoS ONE, Vol 11, Iss 4, p e0154337 (2016)
PLoS ONE, Vol 11, Iss 4, p e0154337 (2016)
Background C677T and A1298C are the most common allelic variants of Methylenetetrahydrofolate Reductase (MTHFR) gene. The association between MTHFR polymorphisms and the occurrence of non-alcoholic fatty liver disease (NAFLD) remains controversial. T
Autor:
Renyi Pang, Changwei Shao, Yangzhen Li, Yuze Niu, Yongwei Zhao, Liu Yang, Song-Lin Chen, Wentao Song, Xiaolin Liao, Guidong Miao, Fengtao Gao
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e52097 (2012)
PLoS ONE
PLoS ONE
High-density genetic linkage maps of half-smooth tongue sole were developed with 1007 microsatellite markers, two SCAR markers and an F1 family containing 94. The female map was composed of 828 markers in 21 linkage groups, covering a total of 1447.3
Autor:
Akihiro Hosaka, Yoshihiro Onouchi, T. Miyata, Kouichi Ozaki, Michiaki Kubo, Takashi Morizono, Mitsuru Matsukura, Hiroyoshi Komai, Tatsuhiko Tsunoda, Atsushi Takahashi, Hideo Kimura, Kunihiro Shigematsu, Toshihiro Tanaka, Hiroshi Shigematsu, Toshiaki Watanabe, Toshifumi Kudo, Yoshinori Inoue
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0139262 (2015)
PLoS ONE
PLoS ONE
Characteristics of peripheral arterial disease (PAD) are the occlusion or stenosis of multiple vessel sites caused mainly by atherosclerosis and chronic lower limb ischemia. To identify PAD susceptible loci, we conducted a genome-wide association stu
Autor:
Annie W.C. Kung, Beom-Jun Kim, Seung Hun Lee, Daniel F. Gudbjartsson, Augustine Kong, Stacey S. Cherny, Anthony W.L. Kwok, Jean Woo, Shin-Yoon Kim, Jung-Min Koh, Jelena Kostic, Stefan T Palsson, Bjarni V. Halldorsson, P. C. Leung, Gunnar Sigurdsson, Timothy Kwok, Solveig Gretarsdottir, Juliana C.N. Chan, Unnur Thorsteinsdottir, Pak C. Sham, Nelson L.S. Tang, Su-Mei Xiao, Ghi Su Kim, Unnur Styrkarsdottir, S Ho, Kari Stefansson
Publikováno v:
PLoS ONE, Vol 5, Iss 10, p e13217 (2010)
PLoS ONE
PLoS ONE; Vol 5
PLoS ONE
PLoS ONE; Vol 5
Most genome-wide association (GWA) studies have focused on populations of European ancestry with limited assessment of the influence of the sequence variants on populations of other ethnicities. To determine whether markers that we have recently show