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Publikováno v:
PLoS ONE, Vol 15, Iss 9 (2020)
PLoS ONE
PLoS ONE, Vol 15, Iss 9, p e0238727 (2020)
PLoS ONE
PLoS ONE, Vol 15, Iss 9, p e0238727 (2020)
PurposeFemale mice have been found to be resistant to streptozotocin (STZ)-induced diabetes, and pre-clinical research related to diabetic complications commonly omits females. The purpose of this study was to develop a method to induce diabetes in f
Publikováno v:
PLoS ONE, Vol 15, Iss 12, p e0243398 (2020)
PLoS ONE
PLoS ONE, Vol 10, Iss 7, p e0134156 (2015)
PLoS ONE
PLoS ONE, Vol 10, Iss 7, p e0134156 (2015)
Objectives Iron overload is now recognized as a health problem in industrialized countries, as excessive iron is highly toxic for liver and spleen. The potential use of curcumin as an iron chelator has not been clearly identified experimentally in ir
Autor:
Andrea Ferrigno, Luca Fabris, Stefano Perlini, Mariapia Vairetti, Luciano Adorini, Clarissa Berardo, Giuseppina Palladini, Plinio Richelmi, Laura Giuseppina Di Pasqua, Massimiliano Cadamuro
Publikováno v:
PLoS ONE, Vol 15, Iss 9 (2020)
PLoS ONE, Vol 15, Iss 9, p e0238543 (2020)
PLoS ONE
PLoS ONE, Vol 15, Iss 9, p e0238543 (2020)
PLoS ONE
BackgroundWe have previously shown that obeticholic acid (OCA) upregulates the biliary excretion of asymmetric dimethylarginine (ADMA), an inhibitor of iNOS regulating the activity of matrix metalloproteinases (MMPs). Here, the effects of OCA on MMP-
Autor:
Michelle M. Estrella, Derek M. Fine, Bryan Lau, Mohamed G. Atta, Bhavna Bhasin, Gregory M. Lucas, George J. Schwartz
Publikováno v:
PLoS ONE, Vol 14, Iss 4, p e0215630 (2019)
[This corrects the article DOI: 10.1371/journal.pone.0082028.].
Autor:
Yeong Jin Choi, Hyeyoung Lee, Byung Ha Chung, Eun-Jee Oh, Chul Woo Yang, Eunhee Han, Ae-Ran Choi, Tae Hyun Ban
Publikováno v:
PLoS ONE
PLoS ONE, Vol 13, Iss 11, p e0207434 (2018)
PLoS ONE, Vol 13, Iss 11, p e0207434 (2018)
Introduction Complement binding activity of donor-specific HLA antibodies (DSA) has been suggested as a new tool to stratify immunologic risk in kidney transplantation (KT). The objective of this study was to evaluate the clinical implication of C1q/
Publikováno v:
PLoS ONE
PLoS ONE, Vol 13, Iss 11, p e0206646 (2018)
PLoS ONE, Vol 13, Iss 11, p e0206646 (2018)
Purpose To investigate the correlation between geographic filling delays in the choriocapillaris using indocyanine green angiography (ICGA) images and dilated vortex veins in central serous chorioretinopathy (CSC). Design Observational case series. P
Autor:
Yunqian Xie, Bing-Shu Wang, Mingliang Tang, Ling Wei, Li Wang, Wenyi Yi, Zhongbiao Fu, Chun Luo, Hailan Ruan, Suiqun Wang, Zhengjin Liu, Liyuan Zhang, Hui-Zhong Xie, Changjiang Liu
Publikováno v:
PLoS ONE
PLoS ONE, Vol 13, Iss 11, p e0206060 (2018)
PLoS ONE, Vol 13, Iss 11, p e0206060 (2018)
BACKGROUND There is no consensus regarding the relationship between HBV DNA and liver fibrosis, and the relationship between HBV DNA and the degree of liver cirrhosis has not been reported in patients with chronic HBV infection. METHODS From January
Publikováno v:
PLoS ONE
PLoS ONE, Vol 13, Iss 11, p e0206504 (2018)
PLoS ONE, Vol 13, Iss 11, p e0206504 (2018)
Smoking is an extremely lethal act and is associated with many illnesses. Lately, major concerns that passive smokers face the same health risks as (if not higher than) active smokers have been raised. Some studies have shown that active smoking is a
Publikováno v:
PLoS ONE
PLoS ONE, Vol 13, Iss 11, p e0206670 (2018)
Repositório Institucional da UnB
Universidade de Brasília (UnB)
instacron:UNB
PLoS ONE, Vol 13, Iss 11, p e0206670 (2018)
Repositório Institucional da UnB
Universidade de Brasília (UnB)
instacron:UNB
Oxidative and inflammatory responses play an important role in the development and prevention of cancer, with both responses being modulated by phytochemical compounds. This study investigated the chemopreventive effect of tucum-do-cerrado fruit in r
Autor:
Tomas Karpati, Itamar Raz, Ran D. Balicer, Maya Leventer-Roberts, Chandra J Cohen-Stavi, Becca Feldman
Publikováno v:
PLoS ONE
PLoS ONE, Vol 13, Iss 11, p e0207096 (2018)
PLoS ONE, Vol 13, Iss 11, p e0207096 (2018)
Aims To identify clinically meaningful clusters of patients with similar glycated hemoglobin (HbA1c) trajectories among patients with type 2 diabetes. Methods A retrospective cohort study using unsupervised machine learning clustering methodologies t