Zobrazeno 1 - 10
of 20
pro vyhledávání: '"M. De Silva"'
Autor:
Laura J. White, Luis D. Giavedoni, James D. Brien, Amelia K. Pinto, Melween I. Martínez, Teresa Arana, Aravinda M. de Silva, Idia V. Rodríguez, L. Parodi, Petraleigh Pantoja, Crisanta Serrano-Collazo, Lorna Cruz, Vida L. Hodara, Mariah Hassert, Erick X. Pérez-Guzmán, Carlos A. Sariol
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 14, Iss 5, p e0008285 (2020)
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases
Little is known about the contribution of virus-specific and cross-reacting antibodies (Abs) or the cellular immune response generated by a primary dengue (DENV) infection on the course of a secondary zika (ZIKV) infection in vivo. Here we show that
Autor:
Elizabeth C. Adams, Aravinda M. de Silva, Ellen F. Young, Laura J. White, Ralph S. Baric, Sandra Henein, Mark Stoops
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 15, Iss 3, p e0009258 (2021)
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases
The four dengue virus serotypes (DENV1-4) infect several hundred million people each year living in tropical and sub-tropical regions. Clinical development of DENV vaccines is difficult because immunity to a single serotype increases risk of severe d
Autor:
Aravinda M. de Silva, Navin Khanna, Rafi Ahmed, Melissa M. Mattocks, Rajgokul K. Shanmugam, Siddhartha Kumar Bhaumik, Ankur Poddar, Rajendra Raut, Rahul Shukla, Poornima Tyagi, Viswanathan Ramasamy, Robert E. Johnston, Sathyamangalam Swaminathan, Murali Krishna Kaja, Francois Villinger, Upasana Arora, Laura J. White, Ashiya Perween
Publikováno v:
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases, Vol 12, Iss 1, p e0006191 (2018)
PLoS Neglected Tropical Diseases, Vol 12, Iss 1, p e0006191 (2018)
Background Dengue is one of the fastest spreading vector-borne diseases, caused by four antigenically distinct dengue viruses (DENVs). Antibodies against DENVs are responsible for both protection as well as pathogenesis. A vaccine that is safe for an
Autor:
Magelda Montoya, Michael J. Miley, Aravinda M. de Silva, Patti Longo, Bhumi Patel, Eva Harris
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 11, Iss 5, p e0005554 (2017)
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases
Dengue viruses (DENVs) are mosquito-borne flaviviruses and the causative agents of dengue fever and dengue hemorrhagic fever. As there are four serotypes of DENV (DENV1-4), people can be infected multiple times, each time with a new serotype. Primary
Autor:
Michelle Stone, Aravinda M. de Silva, Xianwen Yi, Michael J. Miley, Stefan W. Metz, Gabriel Hoekstra, Joseph M. DeSimone, Chris Luft, Katie Horvath, Shaomin Tian
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 10, Iss 10, p e0005071 (2016)
PLoS Neglected Tropical Diseases
PLOS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases
PLOS Neglected Tropical Diseases
Dengue virus (DENV) is the causative agent of dengue fever and dengue hemorrhagic fever. The virus is endemic in over 120 countries, causing over 350 million infections per year. Dengue vaccine development is challenging because of the need to induce
Autor:
Michele Stone, Ashlie Thomas, Aravinda M. de Silva, Katie Horvath, Chris Luft, Stefan W. Metz, Alex Brackbill, Yi Xianwen, Shaomin Tian, Joseph M. DeSimone, Michael J. Miley
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 12, Iss 9, p e0006793 (2018)
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases
Dengue virus (DENV) is the causative agent of dengue fever and dengue hemorrhagic shock syndrome. Dengue vaccine development is challenging because of the need to induce protection against four antigenically distinct DENV serotypes. Recent studies in
Autor:
Orlando Mayorga, Anne Broadwater, Megan E. Reller, Jeremy J. Miles, Christopher W. Woods, Aravinda M. de Silva, Armando Matute, Kathleen R Walker, Ramesh Jadi
Publikováno v:
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases, Vol 10, Iss 10, p e0005026 (2016)
PLoS Neglected Tropical Diseases, Vol 10, Iss 10, p e0005026 (2016)
Background Dengue is an emerging infectious disease of global significance. Suspected dengue, especially in children in Nicaragua’s heavily-urbanized capital of Managua, has been well documented, but unsuspected dengue among children and adults wit
Autor:
Harold S. Margolis, Ananda Amarasinge, Hasitha Tissera, Aravinda M. de Silva, Aruna D. De Silva, Clarence C. Tam
Publikováno v:
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases, Vol 7, Iss 6, p e2259 (2013)
PLoS Neglected Tropical Diseases, Vol 7, Iss 6, p e2259 (2013)
Dengue is the most important vector-borne viral disease worldwide and a major cause of childhood fever burden in Sri Lanka, which has experienced a number of large epidemics in the past decade. Despite this, data on the burden and transmission of den
Autor:
Martina Beltramello, Ralph S. Baric, Quang Pham, Wahala M.P.B. Wahala, Federica Sallusto, Nicholas P. Olivarez, Scott B. Halstead, Wei-Kung Wang, Michael S. Diamond, Ruklanthi de Alwis, Wen-Yang Tsai, James Brian, Aravinda M. de Silva, Soila Sukupolvi-Petty, Srisakul Kliks, Antonio Lanzavecchia, William B. Messer, Annette A. Kraus
Publikováno v:
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases, Vol 5, Iss 6, p e1188 (2011)
PLoS Neglected Tropical Diseases, Vol 5, Iss 6, p e1188 (2011)
Humans who experience a primary dengue virus (DENV) infection develop antibodies that preferentially neutralize the homologous serotype responsible for infection. Affected individuals also generate cross-reactive antibodies against heterologous DENV
Autor:
Eric F. Donaldson, Aravinda M. de Silva, William B. Messer, Boyd Yount, Kari Hacker, Ralph S. Baric, Jeremy P. Huynh
Publikováno v:
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases, Vol 6, Iss 2, p e1486 (2012)
PLoS Neglected Tropical Diseases, Vol 6, Iss 2, p e1486 (2012)
Dengue viruses (DENV) are enveloped single-stranded positive-sense RNA viruses transmitted by Aedes spp. mosquitoes. There are four genetically distinct serotypes designated DENV-1 through DENV-4, each further subdivided into distinct genotypes. The