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Autor:
Posavi M; Department of Neurology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, United States of America., Diaz-Ortiz M; Department of Neurology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, United States of America., Liu B; Department of Neurology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, United States of America., Swanson CR; Department of Neurology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.; National Institute of Neurological Disease and Stroke, National Institutes of Health, Bethesda, Maryland, United States of America., Skrinak RT; Department of Neurology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, United States of America., Hernandez-Con P; Department of Neurology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, United States of America., Amado DA; Department of Neurology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, United States of America., Fullard M; Department of Neurology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, United States of America., Rick J; Department of Neurology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, United States of America., Siderowf A; Department of Neurology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, United States of America., Weintraub D; Department of Psychiatry, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, United States of America., McCluskey L; Department of Neurology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, United States of America., Trojanowski JQ; Department of Pathology and Laboratory Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, United States of America., Dewey RB Jr; Department of Neurology and Neurotherapeutics, Clinical Center for Movement Disorders at the University of Texas Southwestern Medical Center, Dallas, Texas, United States of America., Huang X; Department of Neurology, Penn State College of Medicine, Hershey, Pennsylvania, United States of America., Chen-Plotkin AS; Department of Neurology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.
Publikováno v:
PLoS medicine [PLoS Med] 2019 Oct 11; Vol. 16 (10), pp. e1002931. Date of Electronic Publication: 2019 Oct 11 (Print Publication: 2019).
Autor:
Leo McCluskey, Pilar Hernandez-Con, Xuemei Huang, Defne A. Amado, Michelle E. Fullard, Richard B. Dewey, Marijan Posavi, John Q. Trojanowski, Maria Diaz-Ortiz, Benjamine Liu, Daniel Weintraub, Andrew Siderowf, Jacqueline Rick, Alice Chen-Plotkin, Christine R. Swanson, R. Tyler Skrinak
Publikováno v:
PLoS Medicine, Vol 16, Iss 10, p e1002931 (2019)
PLoS Medicine
PLoS Medicine
Background Parkinson’s disease (PD) is a progressive neurodegenerative disease affecting about 5 million people worldwide with no disease-modifying therapies. We sought blood-based biomarkers in order to provide molecular characterization of indivi