Zobrazeno 1 - 8
of 8
pro vyhledávání: '"David Meyre"'
Autor:
Suzanne Vogelezang, Jonathan P Bradfield, Tarunveer S Ahluwalia, John A Curtin, Timo A Lakka, Niels Grarup, Markus Scholz, Peter J van der Most, Claire Monnereau, Evie Stergiakouli, Anni Heiskala, Momoko Horikoshi, Iryna O Fedko, Natalia Vilor-Tejedor, Diana L Cousminer, Marie Standl, Carol A Wang, Jorma Viikari, Frank Geller, Carmen Íñiguez, Niina Pitkänen, Alessandra Chesi, Jonas Bacelis, Loic Yengo, Maties Torrent, Ioanna Ntalla, Øyvind Helgeland, Saskia Selzam, Judith M Vonk, Mohammed H Zafarmand, Barbara Heude, Ismaa Sadaf Farooqi, Akram Alyass, Robin N Beaumont, Christian T Have, Peter Rzehak, Jose Ramon Bilbao, Theresia M Schnurr, Inês Barroso, Klaus Bønnelykke, Lawrence J Beilin, Lisbeth Carstensen, Marie-Aline Charles, Bo Chawes, Karine Clément, Ricardo Closa-Monasterolo, Adnan Custovic, Johan G Eriksson, Joaquin Escribano, Maria Groen-Blokhuis, Veit Grote, Dariusz Gruszfeld, Hakon Hakonarson, Torben Hansen, Andrew T Hattersley, Mette Hollensted, Jouke-Jan Hottenga, Elina Hyppönen, Stefan Johansson, Raimo Joro, Mika Kähönen, Ville Karhunen, Wieland Kiess, Bridget A Knight, Berthold Koletzko, Andreas Kühnapfel, Kathrin Landgraf, Jean-Paul Langhendries, Terho Lehtimäki, Jaakko T Leinonen, Aihuali Li, Virpi Lindi, Estelle Lowry, Mariona Bustamante, Carolina Medina-Gomez, Mads Melbye, Kim F Michaelsen, Camilla S Morgen, Trevor A Mori, Tenna R H Nielsen, Harri Niinikoski, Albertine J Oldehinkel, Katja Pahkala, Kalliope Panoutsopoulou, Oluf Pedersen, Craig E Pennell, Christine Power, Sijmen A Reijneveld, Fernando Rivadeneira, Angela Simpson, Peter D Sly, Jakob Stokholm, Kook K Teo, Elisabeth Thiering, Nicholas J Timpson, André G Uitterlinden, Catharina E M van Beijsterveldt, Barbera D C van Schaik, Marc Vaudel, Elvira Verduci, Rebecca K Vinding, Mandy Vogel, Eleftheria Zeggini, Sylvain Sebert, Mads V Lind, Christopher D Brown, Loreto Santa-Marina, Eva Reischl, Christine Frithioff-Bøjsøe, David Meyre, Eleanor Wheeler, Ken Ong, Ellen A Nohr, Tanja G M Vrijkotte, Gerard H Koppelman, Robert Plomin, Pål R Njølstad, George D Dedoussis, Philippe Froguel, Thorkild I A Sørensen, Bo Jacobsson, Rachel M Freathy, Babette S Zemel, Olli Raitakari, Martine Vrijheid, Bjarke Feenstra, Leo-Pekka Lyytikäinen, Harold Snieder, Holger Kirsten, Patrick G Holt, Joachim Heinrich, Elisabeth Widén, Jordi Sunyer, Dorret I Boomsma, Marjo-Riitta Järvelin, Antje Körner, George Davey Smith, Jens-Christian Holm, Mustafa Atalay, Clare Murray, Hans Bisgaard, Mark I McCarthy, Early Growth Genetics Consortium, Vincent W V Jaddoe, Struan F A Grant, Janine F Felix
Publikováno v:
PLoS Genetics, Vol 16, Iss 10, p e1008718 (2020)
The genetic background of childhood body mass index (BMI), and the extent to which the well-known associations of childhood BMI with adult diseases are explained by shared genetic factors, are largely unknown. We performed a genome-wide association s
Externí odkaz:
https://doaj.org/article/4ad2f9c3808446e988079e02971d10ee
Autor:
Zari Dastani, Marie-France Hivert, Nicholas Timpson, John R B Perry, Xin Yuan, Robert A Scott, Peter Henneman, Iris M Heid, Jorge R Kizer, Leo-Pekka Lyytikäinen, Christian Fuchsberger, Toshiko Tanaka, Andrew P Morris, Kerrin Small, Aaron Isaacs, Marian Beekman, Stefan Coassin, Kurt Lohman, Lu Qi, Stavroula Kanoni, James S Pankow, Hae-Won Uh, Ying Wu, Aurelian Bidulescu, Laura J Rasmussen-Torvik, Celia M T Greenwood, Martin Ladouceur, Jonna Grimsby, Alisa K Manning, Ching-Ti Liu, Jaspal Kooner, Vincent E Mooser, Peter Vollenweider, Karen A Kapur, John Chambers, Nicholas J Wareham, Claudia Langenberg, Rune Frants, Ko Willems-Vandijk, Ben A Oostra, Sara M Willems, Claudia Lamina, Thomas W Winkler, Bruce M Psaty, Russell P Tracy, Jennifer Brody, Ida Chen, Jorma Viikari, Mika Kähönen, Peter P Pramstaller, David M Evans, Beate St Pourcain, Naveed Sattar, Andrew R Wood, Stefania Bandinelli, Olga D Carlson, Josephine M Egan, Stefan Böhringer, Diana van Heemst, Lyudmyla Kedenko, Kati Kristiansson, Marja-Liisa Nuotio, Britt-Marie Loo, Tamara Harris, Melissa Garcia, Alka Kanaya, Margot Haun, Norman Klopp, H-Erich Wichmann, Panos Deloukas, Efi Katsareli, David J Couper, Bruce B Duncan, Margreet Kloppenburg, Linda S Adair, Judith B Borja, DIAGRAM+ Consortium, MAGIC Consortium, GLGC Investigators, MuTHER Consortium, James G Wilson, Solomon Musani, Xiuqing Guo, Toby Johnson, Robert Semple, Tanya M Teslovich, Matthew A Allison, Susan Redline, Sarah G Buxbaum, Karen L Mohlke, Ingrid Meulenbelt, Christie M Ballantyne, George V Dedoussis, Frank B Hu, Yongmei Liu, Bernhard Paulweber, Timothy D Spector, P Eline Slagboom, Luigi Ferrucci, Antti Jula, Markus Perola, Olli Raitakari, Jose C Florez, Veikko Salomaa, Johan G Eriksson, Timothy M Frayling, Andrew A Hicks, Terho Lehtimäki, George Davey Smith, David S Siscovick, Florian Kronenberg, Cornelia van Duijn, Ruth J F Loos, Dawn M Waterworth, James B Meigs, Josee Dupuis, J Brent Richards, Benjamin F Voight, Laura J Scott, Valgerdur Steinthorsdottir, Christian Dina, Ryan P Welch, Eleftheria Zeggini, Cornelia Huth, Yurii S Aulchenko, Gudmar Thorleifsson, Laura J McCulloch, Teresa Ferreira, Harald Grallert, Najaf Amin, Guanming Wu, Cristen J Willer, Soumya Raychaudhuri, Steve A McCarroll, Oliver M Hofmann, Ayellet V Segrè, Mandy van Hoek, Pau Navarro, Kristin Ardlie, Beverley Balkau, Rafn Benediktsson, Amanda J Bennett, Roza Blagieva, Eric Boerwinkle, Lori L Bonnycastle, Kristina Bengtsson Boström, Bert Bravenboer, Suzannah Bumpstead, Noël P Burtt, Guillaume Charpentier, Peter S Chines, Marilyn Cornelis, Gabe Crawford, Alex S F Doney, Katherine S Elliott, Amanda L Elliott, Michael R Erdos, Caroline S Fox, Christopher S Franklin, Martha Ganser, Christian Gieger, Niels Grarup, Todd Green, Simon Griffin, Christopher J Groves, Candace Guiducci, Samy Hadjadj, Neelam Hassanali, Christian Herder, Bo Isomaa, Anne U Jackson, Paul R V Johnson, Torben Jørgensen, Wen H L Kao, Augustine Kong, Peter Kraft, Johanna Kuusisto, Torsten Lauritzen, Man Li, Aloysius Lieverse, Cecilia M Lindgren, Valeriya Lyssenko, Michel Marre, Thomas Meitinger, Kristian Midthjell, Mario A Morken, Narisu Narisu, Peter Nilsson, Katharine R Owen, Felicity Payne, Ann-Kristin Petersen, Carl Platou, Christine Proença, Inga Prokopenko, Wolfgang Rathmann, N William Rayner, Neil R Robertson, Ghislain Rocheleau, Michael Roden, Michael J Sampson, Richa Saxena, Beverley M Shields, Peter Shrader, Gunnar Sigurdsson, Thomas Sparsø, Klaus Strassburger, Heather M Stringham, Qi Sun, Amy J Swift, Barbara Thorand, Jean Tichet, Tiinamaija Tuomi, Rob M van Dam, Timon W van Haeften, Thijs van Herpt, Jana V van Vliet-Ostaptchouk, G Bragi Walters, Michael N Weedon, Cisca Wijmenga, Jacqueline Witteman, Richard N Bergman, Stephane Cauchi, Francis S Collins, Anna L Gloyn, Ulf Gyllensten, Torben Hansen, Winston A Hide, Graham A Hitman, Albert Hofman, David J Hunter, Kristian Hveem, Markku Laakso, Andrew D Morris, Colin N A Palmer, Igor Rudan, Eric Sijbrands, Lincoln D Stein, Jaakko Tuomilehto, Andre Uitterlinden, Mark Walker, Richard M Watanabe, Goncalo R Abecasis, Bernhard O Boehm, Harry Campbell, Mark J Daly, Andrew T Hattersley, Oluf Pedersen, Inês Barroso, Leif Groop, Rob Sladek, Unnur Thorsteinsdottir, James F Wilson, Thomas Illig, Philippe Froguel, Cornelia M van Duijn, Kari Stefansson, David Altshuler, Michael Boehnke, Mark I McCarthy, Nicole Soranzo, Eleanor Wheeler, Nicole L Glazer, Nabila Bouatia-Naji, Reedik Mägi, Joshua Randall, Paul Elliott, Denis Rybin, Abbas Dehghan, Jouke Jan Hottenga, Kijoung Song, Anuj Goel, Taina Lajunen, Alex Doney, Christine Cavalcanti-Proença, Meena Kumari, Nicholas J Timpson, Carina Zabena, Erik Ingelsson, Ping An, Jeffrey O'Connell, Jian'an Luan, Amanda Elliott, Steven A McCarroll, Rosa Maria Roccasecca, François Pattou, Praveen Sethupathy, Yavuz Ariyurek, Philip Barter, John P Beilby, Yoav Ben-Shlomo, Sven Bergmann, Murielle Bochud, Amélie Bonnefond, Knut Borch-Johnsen, Yvonne Böttcher, Eric Brunner, Suzannah J Bumpstead, Yii-Der Ida Chen, Peter Chines, Robert Clarke, Lachlan J M Coin, Matthew N Cooper, Laura Crisponi, Ian N M Day, Eco J C de Geus, Jerome Delplanque, Annette C Fedson, Antje Fischer-Rosinsky, Nita G Forouhi, Maria Grazia Franzosi, Pilar Galan, Mark O Goodarzi, Jürgen Graessler, Scott Grundy, Rhian Gwilliam, Göran Hallmans, Naomi Hammond, Xijing Han, Anna-Liisa Hartikainen, Caroline Hayward, Simon C Heath, Serge Hercberg, David R Hillman, Aroon D Hingorani, Jennie Hui, Joe Hung, Marika Kaakinen, Jaakko Kaprio, Y Antero Kesaniemi, Mika Kivimaki, Beatrice Knight, Seppo Koskinen, Peter Kovacs, Kirsten Ohm Kyvik, G Mark Lathrop, Debbie A Lawlor, Olivier Le Bacquer, Cécile Lecoeur, Yun Li, Robert Mahley, Massimo Mangino, María Teresa Martínez-Larrad, Jarred B McAteer, Ruth McPherson, Christa Meisinger, David Melzer, David Meyre, Braxton D Mitchell, Sutapa Mukherjee, Silvia Naitza, Matthew J Neville, Marco Orrù, Ruth Pakyz, Giuseppe Paolisso, Cristian Pattaro, Daniel Pearson, John F Peden, Nancy L Pedersen, Andreas F H Pfeiffer, Irene Pichler, Ozren Polasek, Danielle Posthuma, Simon C Potter, Anneli Pouta, Michael A Province, Nigel W Rayner, Kenneth Rice, Samuli Ripatti, Fernando Rivadeneira, Olov Rolandsson, Annelli Sandbaek, Manjinder Sandhu, Serena Sanna, Avan Aihie Sayer, Paul Scheet, Udo Seedorf, Stephen J Sharp, Beverley Shields, Gunnar Sigurðsson, Eric J G Sijbrands, Angela Silveira, Laila Simpson, Andrew Singleton, Nicholas L Smith, Ulla Sovio, Amy Swift, Holly Syddall, Ann-Christine Syvänen, Anke Tönjes, André G Uitterlinden, Ko Willems van Dijk, Dhiraj Varma, Sophie Visvikis-Siest, Veronique Vitart, Nicole Vogelzangs, Gérard Waeber, Peter J Wagner, Andrew Walley, Kim L Ward, Hugh Watkins, Sarah H Wild, Gonneke Willemsen, Jaqueline C M Witteman, John W G Yarnell, Diana Zelenika, Björn Zethelius, Guangju Zhai, Jing Hua Zhao, M Carola Zillikens, DIAGRAM Consortium, GIANT Consortium, Global B Pgen Consortium, Ingrid B Borecki, Pierre Meneton, Patrik K E Magnusson, David M Nathan, Gordon H Williams, Kaisa Silander, Stefan R Bornstein, Peter Schwarz, Joachim Spranger, Fredrik Karpe, Alan R Shuldiner, Cyrus Cooper, Manuel Serrano-Ríos, Lars Lind, Lyle J Palmer, Paul W Franks, Shah Ebrahim, Michael Marmot, W H Linda Kao, Peter Paul Pramstaller, Alan F Wright, Michael Stumvoll, Anders Hamsten, Procardis Consortium, Thomas A Buchanan, Timo T Valle, Jerome I Rotter, Brenda W J H Penninx, Dorret I Boomsma, Antonio Cao, Angelo Scuteri, David Schlessinger, Manuela Uda, Aimo Ruokonen, Marjo-Riitta Jarvelin, Leena Peltonen, Vincent Mooser, Robert Sladek, MAGIC investigators, GLGC Consortium, Kiran Musunuru, Albert V Smith, Andrew C Edmondson, Ioannis M Stylianou, Masahiro Koseki, James P Pirruccello, Daniel I Chasman, Christopher T Johansen, Sigrid W Fouchier, Gina M Peloso, Maja Barbalic, Sally L Ricketts, Joshua C Bis, Mary F Feitosa, Marju Orho-Melander, Olle Melander, Xiaohui Li, Mingyao Li, Yoon Shin Cho, Min Jin Go, Young Jin Kim, Jong-Young Lee, Taesung Park, Kyunga Kim, Xueling Sim, Rick Twee-Hee Ong, Damien C Croteau-Chonka, Leslie A Lange, Joshua D Smith, Andreas Ziegler, Weihua Zhang, Robert Y L Zee, John B Whitfield, John R Thompson, Ida Surakka, Tim D Spector, Johannes H Smit, Juha Sinisalo, James Scott, Juha Saharinen, Chiara Sabatti, Lynda M Rose, Robert Roberts, Mark Rieder, Alex N Parker, Guillaume Pare, Christopher J O'Donnell, Markku S Nieminen, Deborah A Nickerson, Grant W Montgomery, Wendy McArdle, David Masson, Nicholas G Martin, Fabio Marroni, Gavin Lucas, Robert Luben, Marja-Liisa Lokki, Guillaume Lettre, Lenore J Launer, Edward G Lakatta, Reijo Laaksonen, Kirsten O Kyvik, Inke R König, Kay-Tee Khaw, Lee M Kaplan, Åsa Johansson, A Cecile J W Janssens, Wilmar Igl, G Kees Hovingh, Christian Hengstenberg, Aki S Havulinna, Nicholas D Hastie, Tamara B Harris, Talin Haritunians, Alistair S Hall, Leif C Groop, Elena Gonzalez, Nelson B Freimer, Jeanette Erdmann, Kenechi G Ejebe, Angela Döring, Anna F Dominiczak, Serkalem Demissie, Panagiotis Deloukas, Ulf de Faire, Gabriel Crawford, Yii-der I Chen, Mark J Caulfield, S Matthijs Boekholdt, Themistocles L Assimes, Thomas Quertermous, Mark Seielstad, Tien Y Wong, E-Shyong Tai, Alan B Feranil, Christopher W Kuzawa, Herman A Taylor, Stacey B Gabriel, Hilma Holm, Vilmundur Gudnason, Ronald M Krauss, Jose M Ordovas, Patricia B Munroe, Jaspal S Kooner, Alan R Tall, Robert A Hegele, John J P Kastelein, Eric E Schadt, David P Strachan, Muredach P Reilly, Nilesh J Samani, Heribert Schunkert, L Adrienne Cupples, Manjinder S Sandhu, Paul M Ridker, Daniel J Rader, Sekar Kathiresan
Publikováno v:
PLoS Genetics, Vol 8, Iss 3, p e1002607 (2012)
Circulating levels of adiponectin, a hormone produced predominantly by adipocytes, are highly heritable and are inversely associated with type 2 diabetes mellitus (T2D) and other metabolic traits. We conducted a meta-analysis of genome-wide associati
Externí odkaz:
https://doaj.org/article/d72a07536f4c468e8ab94500a1e663a5
Autor:
André Scherag, Christian Dina, Anke Hinney, Vincent Vatin, Susann Scherag, Carla I G Vogel, Timo D Müller, Harald Grallert, H-Erich Wichmann, Beverley Balkau, Barbara Heude, Marjo-Riitta Jarvelin, Anna-Liisa Hartikainen, Claire Levy-Marchal, Jacques Weill, Jérôme Delplanque, Antje Körner, Wieland Kiess, Peter Kovacs, Nigel W Rayner, Inga Prokopenko, Mark I McCarthy, Helmut Schäfer, Ivonne Jarick, Heiner Boeing, Eva Fisher, Thomas Reinehr, Joachim Heinrich, Peter Rzehak, Dietrich Berdel, Michael Borte, Heike Biebermann, Heiko Krude, Dieter Rosskopf, Christian Rimmbach, Winfried Rief, Tobias Fromme, Martin Klingenspor, Annette Schürmann, Nadja Schulz, Markus M Nöthen, Thomas W Mühleisen, Raimund Erbel, Karl-Heinz Jöckel, Susanne Moebus, Tanja Boes, Thomas Illig, Philippe Froguel, Johannes Hebebrand, David Meyre
Publikováno v:
PLoS Genetics, Vol 6, Iss 4, p e1000916 (2010)
Meta-analyses of population-based genome-wide association studies (GWAS) in adults have recently led to the detection of new genetic loci for obesity. Here we aimed to discover additional obesity loci in extremely obese children and adolescents. We a
Externí odkaz:
https://doaj.org/article/03ae334df6704a48ab2b24253c722f85
Autor:
Iris M Heid, Cornelia Huth, Ruth J F Loos, Florian Kronenberg, Vera Adamkova, Sonia S Anand, Kristin Ardlie, Heike Biebermann, Peter Bjerregaard, Heiner Boeing, Claude Bouchard, Marina Ciullo, Jackie A Cooper, Dolores Corella, Christian Dina, James C Engert, Eva Fisher, Francesc Francès, Philippe Froguel, Johannes Hebebrand, Robert A Hegele, Anke Hinney, Margret R Hoehe, Frank B Hu, Jaroslav A Hubacek, Steve E Humphries, Steven C Hunt, Thomas Illig, Marjo-Riita Järvelin, Marika Kaakinen, Barbara Kollerits, Heiko Krude, Jitender Kumar, Leslie A Lange, Birgit Langer, Shengxu Li, Andreas Luchner, Helen N Lyon, David Meyre, Karen L Mohlke, Vincent Mooser, Almut Nebel, Thuy Trang Nguyen, Bernhard Paulweber, Louis Perusse, Lu Qi, Tuomo Rankinen, Dieter Rosskopf, Stefan Schreiber, Shantanu Sengupta, Rossella Sorice, Anita Suk, Gudmar Thorleifsson, Unnur Thorsteinsdottir, Henry Völzke, Karani S Vimaleswaran, Nicholas J Wareham, Dawn Waterworth, Salim Yusuf, Cecilia Lindgren, Mark I McCarthy, Christoph Lange, Joel N Hirschhorn, Nan Laird, H-Erich Wichmann
Publikováno v:
PLoS Genetics, Vol 5, Iss 10, p e1000694 (2009)
The INSIG2 rs7566605 polymorphism was identified for obesity (BMI> or =30 kg/m(2)) in one of the first genome-wide association studies, but replications were inconsistent. We collected statistics from 34 studies (n = 74,345), including general popula
Externí odkaz:
https://doaj.org/article/48b5ddba957d4effaae19a30092a0bee
Autor:
Inês Barroso, Peter D. Sly, Jose Ramon Bilbao, Nicholas J. Timpson, Johan G. Eriksson, Maria M. Groen-Blokhuis, Sijmen A. Reijneveld, Dariusz Gruszfeld, George Davey Smith, Christine Power, Eva Reischl, Mandy Vogel, Andrew T. Hattersley, Øyvind Helgeland, Niina Pitkänen, Akram Alyass, Jean-Paul Langhendries, Elina Hyppönen, Kathrin Landgraf, Loreto Santa-Marina, Frank Geller, Christopher D. Brown, Elvira Verduci, Katja Pahkala, Olli T. Raitakari, Joaquin Escribano, Torben Hansen, Hakon Hakonarson, Barbara Heude, Bridget A. Knight, Maties Torrent, Robin N Beaumont, Judith M. Vonk, Estelle Lowry, Patrick G. Holt, Harold Snieder, Carol A. Wang, Mark I. McCarthy, Christine Frithioff-Bøjsøe, Tanja G. M. Vrijkotte, Natalia Vilor-Tejedor, Lisbeth Carstensen, Catharina E. M. van Beijsterveldt, Ville Karhunen, Virpi Lindi, Marjo-Riitta Järvelin, Tarunveer S. Ahluwalia, Jordi Sunyer, Jaakko T. Leinonen, Clare S. Murray, Klaus Bønnelykke, Thorkild I. A. Sørensen, André G. Uitterlinden, Janine F. Felix, John A. Curtin, Mika Kähönen, Jorma Viikari, Leo-Pekka Lyytikäinen, Oluf Pedersen, Carmen Iñiguez, Harri Niinikoski, Wieland Kiess, Kim F. Michaelsen, Evie Stergiakouli, Anni Heiskala, Alessandra Chesi, Craig E. Pennell, Mohammed H Zafarmand, Peter Rzehak, Kook K Teo, Aihuali Li, Marie Standl, Veit Grote, Momoko Horikoshi, Ellen A. Nohr, Eleanor Wheeler, Rachel M. Freathy, Iryna O. Fedko, Gerard H. Koppelman, Elisabeth Widen, Jens-Christian Holm, Raimo Joro, David Meyre, Mustafa Atalay, Theresia M. Schnurr, Camilla Schmidt Morgen, Adnan Custovic, Niels Grarup, Trevor A. Mori, Terho Lehtimäki, Christian Theil Have, Angela Simpson, Mads Melbye, Bjarke Feenstra, Lawrence J. Beilin, Stefan Johansson, Ioanna Ntalla, Martine Vrijheid, Mariona Bustamante, George Dedoussis, Sylvain Sebert, Jonas Bacelis, Carolina Medina-Gomez, Elisabeth Thiering, Ken K. Ong, Eleftheria Zeggini, Berthold Koletzko, Karine Clément, Bo L. Chawes, Mette Hollensted, Babette S. Zemel, Markus Scholz, Holger Kirsten, Antje Körner, Albertine J. Oldehinkel, Barbera D. C. van Schaik, Philippe Froguel, Vincent W. V. Jaddoe, Dorret I. Boomsma, Struan F.A. Grant, Loic Yengo, Jonathan P. Bradfield, Tenna Ruest Haarmark Nielsen, Suzanne Vogelezang, Jakob Stokholm, Pål R. Njølstad, Bo Jacobsson, Marc Vaudel, Peter J. van der Most, Andreas Kühnapfel, Mads Vendelbo Lind, Timo A. Lakka, Saskia Selzam, Robert Plomin, Marie-Aline Charles, Jouke-Jan Hottenga, Kalliope Panoutsopoulou, Fernando Rivadeneira, Rebecca K. Vinding, Hans Bisgaard, I. S. Farooqi, Joachim Heinrich, Diana L. Cousminer, Ricardo Closa-Monasterolo, Claire Monnereau
Publikováno v:
PLoS Genetics, Vol 16, Iss 10, p e1008718 (2020)
PLoS Genetics
Addi. Archivo Digital para la Docencia y la Investigación
instname
Vogelezang, S, Bradfield, J P, Ahluwalia, T S, Curtin, J A, Grarup, N, Schnurr, T M, Hansen, T, Michaelsen, K F, Pedersen, O B, Stokholm, J, Lind, M V, Frithioff-Bøjsøe, C, Holm, J-C, Felix, J F & Early Growth Genetics Consortium 2020, ' Novel loci for childhood body mass index and shared heritability with adult cardiometabolic traits ', P L o S Genetics, vol. 16, no. 10, e1008718 . https://doi.org/10.1371/journal.pgen.1008718
Vogelezang, S, Bradfield, J P, Ahluwalia, T S, Curtin, J A, Lakka, T A, Grarup, N, Scholz, M, van der Most, P J, Monnereau, C, Stergiakouli, E, Heiskala, A, Horikoshi, M, Fedko, I O, Vilor-Tejedor, N, Cousminer, D L, Standl, M, Wang, C A, Viikari, J, Geller, F, Íñiguez, C, Pitkänen, N, Chesi, A, Bacelis, J, Yengo, L, Torrent, M, Ntalla, I, Helgeland, Ø, Selzam, S, Vonk, J M, Zafarmand, M H, Heude, B, Farooqi, I S, Alyass, A, Beaumont, R N, Have, C T, Rzehak, P, Bilbao, J R, Schnurr, T M, Barroso, I, Bønnelykke, K, Beilin, L J, Carstensen, L, Charles, M A, Chawes, B, Clément, K, Closa-Monasterolo, R, Custovic, A, Hansen, T, Morgen, C S, Nohr, E A & Early Growth Genetics Consortium 2020, ' Novel loci for childhood body mass index and shared heritability with adult cardiometabolic traits ', PLOS Genetics, vol. 16, no. 10, e1008718 . https://doi.org/10.1371/journal.pgen.1008718
PLOS Genetics
PLoS Genetics (online), 16(10):e1008718. Public Library of Science
PLoS genetics, 16(10):e1008718. Public Library of Science
PLoS Genetics, Public Library of Science, 2020, 16 (10), pp.e1008718. ⟨10.1371/journal.pgen.1008718⟩
e1008718
PLOS GENETICS
r-FISABIO: Repositorio Institucional de Producción Científica
Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO)
Fedko, I O, Groen-Blokhuis, M, Hottenga, J-J, Van Beijsterveldt, C E M, Vrijkotte, T G M, Boomsma, D I & Early Growth Genetics (EGG) Consortium 2020, ' Novel loci for childhood body mass index and shared heritability with adult cardiometabolic traits ', PLoS Genetics, vol. 16, no. 10, e1008718, pp. 1-26 . https://doi.org/10.1371/journal.pgen.1008718
PLoS Genetics, 2020, 16 (10), pp.e1008718. ⟨10.1371/journal.pgen.1008718⟩
PLoS Genetics, 16(10):e1008718, 1-26. Public Library of Science
Addi: Archivo Digital para la Docencia y la Investigación
Universidad del País Vasco
r-FISABIO. Repositorio Institucional de Producción Científica
Curtin, J, Murray, C & et al. 2020, ' Novel loci for childhood body mass index and shared heritability with adult cardiometabolic traits ', PL o S Genetics . https://doi.org/10.1371/journal.pgen.1008718
PLoS genetics, 16(10):e1008718. PUBLIC LIBRARY SCIENCE
PLoS Genet. 16:e1008718 (2020)
PLoS Genetics
Addi. Archivo Digital para la Docencia y la Investigación
instname
Vogelezang, S, Bradfield, J P, Ahluwalia, T S, Curtin, J A, Grarup, N, Schnurr, T M, Hansen, T, Michaelsen, K F, Pedersen, O B, Stokholm, J, Lind, M V, Frithioff-Bøjsøe, C, Holm, J-C, Felix, J F & Early Growth Genetics Consortium 2020, ' Novel loci for childhood body mass index and shared heritability with adult cardiometabolic traits ', P L o S Genetics, vol. 16, no. 10, e1008718 . https://doi.org/10.1371/journal.pgen.1008718
Vogelezang, S, Bradfield, J P, Ahluwalia, T S, Curtin, J A, Lakka, T A, Grarup, N, Scholz, M, van der Most, P J, Monnereau, C, Stergiakouli, E, Heiskala, A, Horikoshi, M, Fedko, I O, Vilor-Tejedor, N, Cousminer, D L, Standl, M, Wang, C A, Viikari, J, Geller, F, Íñiguez, C, Pitkänen, N, Chesi, A, Bacelis, J, Yengo, L, Torrent, M, Ntalla, I, Helgeland, Ø, Selzam, S, Vonk, J M, Zafarmand, M H, Heude, B, Farooqi, I S, Alyass, A, Beaumont, R N, Have, C T, Rzehak, P, Bilbao, J R, Schnurr, T M, Barroso, I, Bønnelykke, K, Beilin, L J, Carstensen, L, Charles, M A, Chawes, B, Clément, K, Closa-Monasterolo, R, Custovic, A, Hansen, T, Morgen, C S, Nohr, E A & Early Growth Genetics Consortium 2020, ' Novel loci for childhood body mass index and shared heritability with adult cardiometabolic traits ', PLOS Genetics, vol. 16, no. 10, e1008718 . https://doi.org/10.1371/journal.pgen.1008718
PLOS Genetics
PLoS Genetics (online), 16(10):e1008718. Public Library of Science
PLoS genetics, 16(10):e1008718. Public Library of Science
PLoS Genetics, Public Library of Science, 2020, 16 (10), pp.e1008718. ⟨10.1371/journal.pgen.1008718⟩
e1008718
PLOS GENETICS
r-FISABIO: Repositorio Institucional de Producción Científica
Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO)
Fedko, I O, Groen-Blokhuis, M, Hottenga, J-J, Van Beijsterveldt, C E M, Vrijkotte, T G M, Boomsma, D I & Early Growth Genetics (EGG) Consortium 2020, ' Novel loci for childhood body mass index and shared heritability with adult cardiometabolic traits ', PLoS Genetics, vol. 16, no. 10, e1008718, pp. 1-26 . https://doi.org/10.1371/journal.pgen.1008718
PLoS Genetics, 2020, 16 (10), pp.e1008718. ⟨10.1371/journal.pgen.1008718⟩
PLoS Genetics, 16(10):e1008718, 1-26. Public Library of Science
Addi: Archivo Digital para la Docencia y la Investigación
Universidad del País Vasco
r-FISABIO. Repositorio Institucional de Producción Científica
Curtin, J, Murray, C & et al. 2020, ' Novel loci for childhood body mass index and shared heritability with adult cardiometabolic traits ', PL o S Genetics . https://doi.org/10.1371/journal.pgen.1008718
PLoS genetics, 16(10):e1008718. PUBLIC LIBRARY SCIENCE
PLoS Genet. 16:e1008718 (2020)
The genetic background of childhood body mass index (BMI), and the extent to which the well-known associations of childhood BMI with adult diseases are explained by shared genetic factors, are largely unknown. We performed a genome-wide association s
Autor:
Anke Hinney, Barbara Heude, Christian Rimmbach, Ivonne Jarick, Peter Kovacs, Heike Biebermann, Susann Scherag, Vincent Vatin, Marjo-Riitta Järvelin, André Scherag, Inga Prokopenko, Claire Levy-Marchal, Dietrich Berdel, Karl-Heinz Jöckel, Joachim Heinrich, Tanja Boes, Raimund Erbel, Peter Rzehak, Eva Fisher, Wieland Kiess, Tobias Fromme, Jérôme Delplanque, Anna-Liisa Hartikainen, Beverley Balkau, Carla I. G. Vogel, Martin Klingenspor, Christian Dina, Jacques Weill, Markus M. Nöthen, Winfried Rief, Annette Schürmann, Timo D. Müller, Harald Grallert, Philippe Froguel, Nigel W. Rayner, Susanne Moebus, Thomas Illig, Thomas W. Mühleisen, Helmut Schäfer, Johannes Hebebrand, David Meyre, Mark I. McCarthy, Dieter Rosskopf, Michael Borte, Heiner Boeing, Thomas Reinehr, Nadja Schulz, Antje Körner, H.-Erich Wichmann, Heiko Krude
Publikováno v:
PLoS Genetics, Vol 6, Iss 4, p e1000916 (2010)
PLoS Genet. 6:e1000916 (2010)
PLoS Genet. 6:e1000916 (2010)
Meta-analyses of population-based genome-wide association studies (GWAS) in adults have recently led to the detection of new genetic loci for obesity. Here we aimed to discover additional obesity loci in extremely obese children and adolescents. We a
Autor:
Seppo Koskinen, Christian Herder, Daniel I. Chasman, Andrew R. Wood, Jonna L. Grimsby, J.F. Wilson, Day Inm., Massimo Mangino, Gonneke Willemsen, Robert W. Mahley, Cristian Pattaro, Nicole L. Glazer, T.B. Harris, Irene Pichler, M S Sandhu, D. van Heemst, Christine Proença, Martha Ganser, Robert A. Hegele, Richa Saxena, Eleftheria Zeggini, Markku Laakso, Peter Kraft, Judith B. Borja, Karen L. Mohlke, J B Richards, de Geus Ejc., Robert Sladek, Cristen J. Willer, Samy Hadjadj, S.M. Boekholdt, Gina M. Peloso, Kijoung Song, Sutapa Mukherjee, Gudmar Thorleifsson, Winston Hide, Mark I. McCarthy, Ruth E. Pakyz, Marian Beekman, Ayellet V. Segrè, Inga Prokopenko, Ping An, George Dedoussis, Danielle Posthuma, Jeanette Erdmann, Simon J. Griffin, Nilesh J. Samani, Inke R. König, Frank B. Hu, Lokki M-L., David M. Evans, Xiaohui Li, Valgerdur Steinthorsdottir, Aimo Ruokonen, A Pouta, Kerrin S. Small, Cecilia M. Lindgren, O Le Bacquer, Xijing Han, Florian Kronenberg, E Katsareli, Christian Dina, S. Gabriel, Jochen Spranger, James S. Pankow, M. Kloppenburg, Penninx Bwjh., Torben Hansen, Josh Smith, Jennie Hui, Gordon H. Williams, Mark Seielstad, Ingrid B. Borecki, Weihua Zhang, Peter P. Pramstaller, Stephen J. Sharp, Neil R. Robertson, Zee Ryl., Mike Sampson, Angela Silveira, C.M. van Duijn, Anders Hamsten, Peter Shrader, Denis Rybin, Chen Y-Di., Gunnar Sigurdsson, Michael Stumvoll, Russel Tracy, Mark O. Goodarzi, Göran Hallmans, Michael R. Erdos, Valeriya Lyssenko, Juha Saharinen, Sven Bergmann, Jeffrey R. O'Connell, Debbie A Lawlor, Thomas Meitinger, Yvonne Böttcher, Jérôme Delplanque, Sarah G. Buxbaum, Silvia Naitza, Shah Ebrahim, Graham A. Hitman, Angelo Scuteri, Aroon D. Hingorani, Heribert Schunkert, François Pattou, Claudia Lamina, A L Elliott, Sekar Kathiresan, Dawn M. Waterworth, Jennifer A. Brody, Thomas Quertermous, Leena Peltonen, Josephine M. Egan, Daniel J. Rader, J F Peden, Yarnell Jwg., Daniel S. Pearson, Pfeiffer Afh., P S Chines, N Vogelzangs, Susan Redline, Alka M. Kanaya, T B Harris, J. V. van Vliet-Ostaptchouk, Ghislain Rocheleau, Rune R. Frants, Olga D. Carlson, James G. Wilson, Melissa Garcia, Ong Rt-H., Mark J. Caulfield, Tanya M. Teslovich, Loo B-M., Beatrice Knight, Andreas Ziegler, Claudia Langenberg, Yoon Shin Cho, Paul M. Ridker, Mark J. Rieder, Praveen Sethupathy, Bert Bravenboer, J. Viikari, Matt Neville, Ioannis M. Stylianou, Andrew Walley, Jarvelin M-R., Jarred B. McAteer, Ronald M. Krauss, Augustine Kong, Oluf Pedersen, Mark J. Daly, Andrew P. Morris, Anna F. Dominiczak, Stéphane Cauchi, Michael Boehnke, Christopher J. O'Donnell, Barbara Thorand, Peter M. Nilsson, Aaron Isaacs, Deborah A. Nickerson, Roza Blagieva, Mary F. Feitosa, Nicholas J. Wareham, Robert Roberts, J S Kooner, K W van Dijk, Tiinamaija Tuomi, Paul Scheet, Lynda M. Rose, Albert V. Smith, Rafn Benediktsson, Chiara Sabatti, Candace Guiducci, Lee M. Kaplan, Aki S. Havulinna, Toby Johnson, Samuli Ripatti, Erik Ingelsson, Mario A. Morken, Carl G. P. Platou, Anke Tönjes, Qi Sun, Narisu Narisu, S J Bumpstead, Jose M. Ordovas, Alan B. Feranil, L Groop, P Chines, Sara M. Willems, Perry Jrb., Matthew A. Allison, Jan Scott, Cécile Lecoeur, Kastelein Jjp., Herman A. Taylor, Anyuan Cao, Christopher J. Groves, Lincoln D. Stein, Laura J. Scott, John Beilby, Kristin G. Ardlie, Christopher S. Franklin, Yoav Ben-Shlomo, B M Shields, N J Timpson, Marco Orrù, Amélie Bonnefond, Kiran Musunuru, Murielle Bochud, Udo Seedorf, Yongmei Liu, Guillaume Lettre, Lee J-Y., Alan R. Shuldiner, Ryan P. Welch, David J. Hunter, John Whitfield, Klaus Strassburger, Khaw K-T., Hartikainen A-L., Gunnar Sigurðsson, Lu Qi, Richard N. Bergman, G M Lathrop, Sigrid W. Fouchier, T van Herpt, David S. Siscovick, Igor Rudan, Richard M. Watanabe, Themistocles L. Assimes, Nicholas G. Martin, Ozren Polasek, Dhiraj Varma, K Kim, Oliver Hofmann, Nicholas D. Hastie, S Bumpstead, Jose C. Florez, Fernando Rivadeneira, Katharine R. Owen, Braxton D. Mitchell, Alisa K. Manning, Abbas Dehghan, Bruce Bartholow Duncan, Cisca Wijmenga, Timo T. Valle, Jaakko Kaprio, Mika Kivimäki, B Shields, Laila Simpson, Tim D. Spector, Paul W. Franks, Guangju Zhai, María Teresa Martínez-Larrad, Janssens Acjw., Kim L. Ward, Inês Barroso, Xiuqing Guo, Rosa Maria Roccasecca, Zari Dastani, Reijo Laaksonen, Wilmar Igl, Vincent Mooser, Niels Grarup, Cornelia Huth, Christian Gieger, Fabio Marroni, Jaakko Tuomilehto, Doney Asf., Andrew C. Edmondson, Christian Fuchsberger, Meena Kumari, David M. Nathan, Reedik Mägi, Solomon K. Musani, U de Faire, Knut Borch-Johnsen, Masahiro Koseki, Giuseppe Paolisso, Norman Klopp, Caroline S. Fox, Nelson B. Freimer, Mika Kähönen, Peter Henneman, Diana Zelenika, K Willems-Vandijk, Steven A. McCarroll, Paul Elliott, Wichmann H-E., J. C. Bis, Nita G. Forouhi, Antti Jula, Witteman Jcm., Fredrik Karpe, Joseph Hung, Antje Fischer-Rosinsky, Eric J. Brunner, Elena Gonzalez, Soumya Raychaudhuri, Jian'an Luan, Josée Dupuis, Joshua C. Randall, Taesung Park, Francis S. Collins, Lori L. Bonnycastle, Andrew A. Hicks, Peter Kovacs, Thomas Illig, Maja Barbalić, David Couper, Jaspal S. Kooner, Damien C. Croteau-Chonka, Gavin Lucas, P J Wagner, Young-Jin Kim, Yurii S. Aulchenko, Aurelian Bidulescu, Ingrid Meulenbelt, Pilar Galan, Iris M. Heid, Michael N. Weedon, Serena Sanna, Sarah H. Wild, Hivert M-F., Patricia B. Munroe, Johan G. Eriksson, Teresa Ferreira, Robert A. Scott, A. Sandbaek, Kenneth Rice, Veronique Vitart, Xin Yuan, Leslie A. Lange, Hilma Holm, Jorge R. Kizer, Timothy M. Frayling, Marika Kaakinen, Liu C-T., Petersen A-K., Peter Schwarz, G B Walters, Palmer Cna., Jean Tichet, Bernhard Paulweber, Ying Wu, Alyson Hall, Christopher T. Johansen, David Masson, Martin Ladouceur, Christie M. Ballantyne, Tai E-S., Robert Luben, Guillaume Charpentier, Angela Döring, Philip J. Barter, Ruth McPherson, Benjamin F. Voight, Wolfgang Rathmann, Mark Walker, Markus Perola, M. A. Province, Veikko Salomaa, James B. Meigs, George Davey Smith, Robert Clarke, Gerard Waeber, Stefania Bandinelli, Sally L. Ricketts, Kaisa Silander, Loos Rjf., Amanda J. Bennett, John C. Chambers, Marilyn C. Cornelis, L A Cupples, Andrew T. Hattersley, M Sandhu, Marju Orho-Melander, C M van Duijn, Olli T. Raitakari, David Meyre, Ida Surakka, Jouke-Jan Hottenga, Uh H-W., Kari Stefansson, David Melzer, P E Slagboom, Kristian Midthjell, Robert K. Semple, James P. Pirruccello, Aloysius G Lieverse, Åsa Johansson, Michael Roden, Felicity Payne, Eric J.G. Sijbrands, N P Burtt, David R. Hillman, Michael Marmot, Todd Green, Eric E. Schadt, Sijbrands Ejg., Tien Yin Wong, Coin Ljm., K B Boström, Olov Rolandsson, A D Morris, David Altshuler, Harald Grallert, L C Groop, Alan F. Wright, Karen Kapur, Xueling Sim, Philippe Froguel, K O Kyvik, T. Lauritzen, Linda S. Adair, Yavuz Ariyurek, Talin Haritunians, Toshiko Tanaka, Albert Hofman, MariaGrazia Franzosi, Nicholas L. Smith, Laura Crisponi, Andrew B. Singleton, A Uitterlinden, Bo Isomaa, Y A Kesaniemi, Anne U. Jackson, Christa Meisinger, Holly E. Syddall, Dorret I. Boomsma, Harry Campbell, Gonçalo R. Abecasis, Lyudmyla Kedenko, Christine Cavalcanti-Proença, G Crawford, Scott M. Grundy, Johnson Prv., Nuotio M-L., I Chen, J.H. Smit, Anuj Goel, M Li, David P. Strachan, Kenechi Ejebe, Beverley Balkau, Neelam Hassanali, Kristian Hveem, Pierre Meneton, R. Gwilliam, A J Swift, Caroline Hayward, J. Graessler, Carina Zabena, B. St Pourcain, Michel Marre, Margot Haun, Lyytikäinen L-P., Ben A. Oostra, Stefan Coassin, M. van Hoek, Nigel W. Rayner, John R. Thompson, Kurt Lohman, Ulla Sovio, Unnur Thorsteinsdottir, Naveed Sattar, Lyle J. Palmer, Ulf Gyllensten, A Elliott, Muredach P. Reilly, A Swift, Luigi Ferrucci, Syvänen A-C., Simon C. Potter, T.W. van Haeften, G Wu, Stefan Böhringer, Grant W. Montgomery, Edward G. Lakatta, Serkalem Demissie, Alex S. F. Doney, Najaf Amin, Lenore J. Launer, Hugh Watkins, Johanna Kuusisto, Lars Lind, Stefan R. Bornstein, Laura J. Rasmussen-Torvik, Terho Lehtimäki, Guillaume Paré, Sophie Visvikis-Siest, S C Heath, David Schlessinger, Juha Sinisalo, Kao Whl., Mark E. Cooper, Kati Kristiansson, Thomas W. Winkler, Thomas Sparsø, Laura J. McCulloch, Taina K. Lajunen, Alex N. Parker, Nabila Bouatia-Naji, Markku S. Nieminen, Peter Vollenweider, Wendy L. McArdle, G K Hovingh, Thomas A. Buchanan, Avan Aihie Sayer, M C Zillikens, Jing Hua Zhao, Naomi Hammond, Vilmundur Gudnason, Björn Zethelius, Panos Deloukas, Jacqueline C. M. Witteman, Eric Boerwinkle, Manuel Serrano-Ríos, Anna L. Gloyn, Katherine S. Elliott, A C Fedson, Torben Jørgensen, Nicole Soranzo, Heather M. Stringham, Bruce M. Psaty, A G Uitterlinden, Stavroula Kanoni, Christian Hengstenberg, Yun Li, Olle Melander, Alan R. Tall, Manuela Uda, Magnusson Pke., Christopher W. Kuzawa, V Mooser, R. M. van Dam, Jerome I. Rotter, Greenwood Cmt., Cyrus Cooper, Pau Navarro, Min Jin Go, Nancy L. Pedersen, Serge Hercberg, Bernhard O. Boehm, Eleanor Wheeler
Publikováno v:
PLoS Genetics; Vol 8
Dastani, Z, Hivert, M F, Timpson, N J, Perry, J R, Yuan, X, Scott, R A, Henneman, P, Heid, I M, Kizer, J R, Lyytikäinen, L P, Fuchsberger, C, Tanaka, T, Morris, A P, Small, K, Isaacs, A, Beekman, M, Coassin, S, Lohman, K, Qi, L, Kanoni, S, Pankow, J S, Uh, H W, Wu, Y, Bidulescu, A, Rasmussen-Torvik, L J, Greenwood, C M, Ladouceur, M, Grimsby, J, Manning, A K, Liu, C T, Kooner, J, Mooser, V E, Vollenweider, P, Kapur, K A, Chambers, J, Wareham, N J, Langenberg, C, Frants, R, Willems van Dijk, K, Oostra, B A, Willems, S M, Lamina, C, Winkler, T W, Psaty, B M, Tracy, R P, Brody, J, Chen, I, Viikari, J, Kähönen, M, Pramstaller, P P, Evans, D M, St Pourcain, B, Sattar, N, Wood, A R, Bandinelli, S, Carlson, O D, Egan, J M, Böhringer, S, van Heemst, D, Kedenko, L, Kristiansson, K, Nuotio, M L, Loo, B M, Harris, T, Garcia, M, Kanaya, A, Haun, M, Klopp, N, Wichmann, H E, Deloukas, P, Katsareli, E, Couper, D J, Duncan, B B, Kloppenburg, M, Adair, L S, Borja, J B, Hottenga, J J, de Geus, E J C, Willemsen, G, Boomsma, D I, Wilson, J G, Musani, G, Guo, X, Johnson, T, Semple, R, Teslovich, T M, Allison, M A, Redline, S, Buxbaum, S G, Mohlke, K L, Meulenbelt, I, Ballantyne, C M, Dedoussis, G V, Hu, F B, Liu, Y, Paulweber, B, Spector, T D, Slagboom, P E, Ferrucci, L, Jula, A, Perola, M, Raitakari, O, Florez, J C, Salomaa, V, Eriksson, J G, Frayling, T M, Hicks, A A, Lehtimäki, T, Smith, G D, Siscovick, D S, Kronenberg, F, van Duijn, C M, Loos, R J, Waterworth, D, Meigs, J B, Dupuis, J, Richards, J B, Posthuma, D, Penninx, B W J H, Vogelzangs, N & Kathiresan, S 2012, ' Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals ', PLoS Genetics, vol. 8, no. 3, e1002607, pp. e1002607 . https://doi.org/10.1371/journal.pgen.1002607
Plos Genetics, 8(3). Public Library of Science
PLoS Genet. 8:e1002607 (2012)
DIAGRAM+ Consortium, MAGIC Consortium & GLGC Consortium 2012, ' Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits : a multi-ethnic meta-analysis of 45,891 individuals ', P L o S Genetics, vol. 8, no. 3, pp. e1002607 . https://doi.org/10.1371/journal.pgen.1002607
PLoS Genetics (print), 8(3). Public Library of Science
Dastani, Z, Hivert, M-F, Timpson, N, Perry, J R B, Yuan, X, Scott, R A, Henneman, P, Heid, I M, Kizer, J R, Lyytikäinen, L-P, Fuchsberger, C, Tanaka, T, Morris, A P, Small, K, Isaacs, A, Beekman, M, Coassin, S, Lohman, K, Qi, L, Kanoni, S, Pankow, J S, Uh, H-W, Wu, Y, Bidulescu, A, Rasmussen-Torvik, L J, Greenwood, C M T, Ladouceur, M, Grimsby, J, Manning, A K, Liu, C-T, Kooner, J, Mooser, V E, Vollenweider, P, Kapur, K A, Chambers, J, Wareham, N J, Langenberg, C, Wilson, J G, Navarro, P, Morris, A, Rudan, I, Campbell, H, Wilson, J F, Hayward, C, Sharp, S J, Vitart, V, Wild, S H, Wright, A F & Thompson, J R & Hastie, N D 2012, ' Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits : a multi-ethnic meta-analysis of 45,891 individuals ', PLoS Genetics, vol. 8, no. 3, pp. e1002607 . https://doi.org/10.1371/journal.pgen.1002607
PLoS Genetics, 8(3)
PLoS Genetics, Vol 8, Iss 3, p e1002607 (2012)
PLoS Genetics
PLoS Genetics, 8(3):e1002607. Public Library of Science
PLoS genetics, 8(3). Public Library of Science
Dastani, Z, Hivert, M-F, Timpson, N, Perry, J R B, Yuan, X, Scott, R A, Henneman, P, Heid, I M, Kizer, J R, Lyytikäinen, L-P, Fuchsberger, C, Tanaka, T, Morris, A P, Small, K, Isaacs, A, Beekman, M, Coassin, S, Lohman, K, Qi, L, Kanoni, S, Pankow, J S, Uh, H-W, Wu, Y, Bidulescu, A, Rasmussen-Torvik, L J, Greenwood, C M T, Ladouceur, M, Grimsby, J, Manning, A K, Liu, C-T, Kooner, J, Mooser, V E, Vollenweider, P, Kapur, K A, Chambers, J, Wareham, N J, Langenberg, C, Frants, R, Willems-Vandijk, K, Oostra, B A, Willems, S M, Lamina, C, Winkler, T W, Psaty, B M, Tracy, R P, Brody, J, Chen, I, Borch-Johnsen, K, Kyvik, K O & DIAGRAM Consortium 2012, ' Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits : a multi-ethnic meta-analysis of 45,891 individuals ', P L o S Genetics, vol. 8, no. 3, pp. e1002607 . https://doi.org/10.1371/journal.pgen.1002607
Plos Genetics, vol. 8, no. 3, pp. e1002607
Dastani, Z, Hivert, M F, Timpson, N J, Perry, J R, Yuan, X, Scott, R A, Henneman, P, Heid, I M, Kizer, J R, Lyytikäinen, L P, Fuchsberger, C, Tanaka, T, Morris, A P, Small, K, Isaacs, A, Beekman, M, Coassin, S, Lohman, K, Qi, L, Kanoni, S, Pankow, J S, Uh, H W, Wu, Y, Bidulescu, A, Rasmussen-Torvik, L J, Greenwood, C M, Ladouceur, M, Grimsby, J, Manning, A K, Liu, C T, Kooner, J, Mooser, V E, Vollenweider, P, Kapur, K A, Chambers, J, Wareham, N J, Langenberg, C, Frants, R, Willems van Dijk, K, Oostra, B A, Willems, S M, Lamina, C, Winkler, T W, Psaty, B M, Tracy, R P, Brody, J, Chen, I, Viikari, J, Kähönen, M, Pramstaller, P P, Evans, D M, St Pourcain, B, Sattar, N, Wood, A R, Bandinelli, S, Carlson, O D, Egan, J M, Böhringer, S, van Heemst, D, Kedenko, L, Kristiansson, K, Nuotio, M L, Loo, B M, Harris, T, Garcia, M, Kanaya, A, Haun, M, Klopp, N, Wichmann, H E, Deloukas, P, Katsareli, E, Couper, D J, Duncan, B B, Kloppenburg, M, Adair, L S, Borja, J B, Hottenga, J J, de Geus, E J C, Willemsen, G, Boomsma, D I, Wilson, J G, Musani, G, Guo, X, Johnson, T, Semple, R, Teslovich, T M, Allison, M A, Redline, S, Buxbaum, S G, Mohlke, K L, Meulenbelt, I, Ballantyne, C M, Dedoussis, G V, Hu, F B, Liu, Y, Paulweber, B, Spector, T D, Slagboom, P E, Ferrucci, L, Jula, A, Perola, M, Raitakari, O, Florez, J C, Salomaa, V, Eriksson, J G, Frayling, T M, Hicks, A A, Lehtimäki, T, Smith, G D, Siscovick, D S, Kronenberg, F, van Duijn, C M, Loos, R J, Waterworth, D, Meigs, J B, Dupuis, J, Richards, J B, Posthuma, D, Penninx, B W J H, Vogelzangs, N & Kathiresan, S 2012, ' Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals ', PLoS Genetics, vol. 8, no. 3, e1002607, pp. e1002607 . https://doi.org/10.1371/journal.pgen.1002607
Plos Genetics, 8(3). Public Library of Science
PLoS Genet. 8:e1002607 (2012)
DIAGRAM+ Consortium, MAGIC Consortium & GLGC Consortium 2012, ' Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits : a multi-ethnic meta-analysis of 45,891 individuals ', P L o S Genetics, vol. 8, no. 3, pp. e1002607 . https://doi.org/10.1371/journal.pgen.1002607
PLoS Genetics (print), 8(3). Public Library of Science
Dastani, Z, Hivert, M-F, Timpson, N, Perry, J R B, Yuan, X, Scott, R A, Henneman, P, Heid, I M, Kizer, J R, Lyytikäinen, L-P, Fuchsberger, C, Tanaka, T, Morris, A P, Small, K, Isaacs, A, Beekman, M, Coassin, S, Lohman, K, Qi, L, Kanoni, S, Pankow, J S, Uh, H-W, Wu, Y, Bidulescu, A, Rasmussen-Torvik, L J, Greenwood, C M T, Ladouceur, M, Grimsby, J, Manning, A K, Liu, C-T, Kooner, J, Mooser, V E, Vollenweider, P, Kapur, K A, Chambers, J, Wareham, N J, Langenberg, C, Wilson, J G, Navarro, P, Morris, A, Rudan, I, Campbell, H, Wilson, J F, Hayward, C, Sharp, S J, Vitart, V, Wild, S H, Wright, A F & Thompson, J R & Hastie, N D 2012, ' Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits : a multi-ethnic meta-analysis of 45,891 individuals ', PLoS Genetics, vol. 8, no. 3, pp. e1002607 . https://doi.org/10.1371/journal.pgen.1002607
PLoS Genetics, 8(3)
PLoS Genetics, Vol 8, Iss 3, p e1002607 (2012)
PLoS Genetics
PLoS Genetics, 8(3):e1002607. Public Library of Science
PLoS genetics, 8(3). Public Library of Science
Dastani, Z, Hivert, M-F, Timpson, N, Perry, J R B, Yuan, X, Scott, R A, Henneman, P, Heid, I M, Kizer, J R, Lyytikäinen, L-P, Fuchsberger, C, Tanaka, T, Morris, A P, Small, K, Isaacs, A, Beekman, M, Coassin, S, Lohman, K, Qi, L, Kanoni, S, Pankow, J S, Uh, H-W, Wu, Y, Bidulescu, A, Rasmussen-Torvik, L J, Greenwood, C M T, Ladouceur, M, Grimsby, J, Manning, A K, Liu, C-T, Kooner, J, Mooser, V E, Vollenweider, P, Kapur, K A, Chambers, J, Wareham, N J, Langenberg, C, Frants, R, Willems-Vandijk, K, Oostra, B A, Willems, S M, Lamina, C, Winkler, T W, Psaty, B M, Tracy, R P, Brody, J, Chen, I, Borch-Johnsen, K, Kyvik, K O & DIAGRAM Consortium 2012, ' Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits : a multi-ethnic meta-analysis of 45,891 individuals ', P L o S Genetics, vol. 8, no. 3, pp. e1002607 . https://doi.org/10.1371/journal.pgen.1002607
Plos Genetics, vol. 8, no. 3, pp. e1002607
Circulating levels of adiponectin, a hormone produced predominantly by adipocytes, are highly heritable and are inversely associated with type 2 diabetes mellitus (T2D) and other metabolic traits. We conducted a meta-analysis of genome-wide associati
Autor:
Ruth J. F. Loos, Stefan Schreiber, Claude Bouchard, Unnur Thorsteinsdottir, Barbara Kollerits, Karani Santhanakrishnan Vimaleswaran, Shantanu Sengupta, Bernhard Paulweber, Rossella Sorice, Robert A. Hegele, Margret R. Hoehe, Thuy Trang Nguyen, Lu Qi, Gudmar Thorleifsson, Tuomo Rankinen, Cecilia M. Lindgren, Philippe Froguel, James C. Engert, Andreas Luchner, Karen L. Mohlke, Dieter Rosskopf, Almut Nebel, Francesc Francés, Henry Völzke, Steve E. Humphries, Helen N. Lyon, Vincent Mooser, Nan M. Laird, Steven C. Hunt, Jitender Kumar, Florian Kronenberg, Salim Yusuf, Thomas Illig, M. R. Järvelin, Christoph Lange, Anke Hinney, Christian Dina, Sonia S. Anand, Jackie A. Cooper, Birgit Langer, Iris M. Heid, Nicholas J. Wareham, Vera Adamkova, Kristin G. Ardlie, Louis Pérusse, Johannes Hebebrand, Cornelia Huth, Dolores Corella, Anita Suk, Peter Bjerregaard, Heike Biebermann, Eva Fisher, Dawn M. Waterworth, Marika Kaakinen, Shengxu Li, Leslie A. Lange, David Meyre, Jaroslav A. Hubacek, H-Erich Wichmann, Marina Ciullo, Heiko Krude, Mark I. McCarthy, Joel N. Hirschhorn, Frank B. Hu, Heiner Boeing
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 5, Iss 10, p e1000694 (2009)
Robarts Vascular Research Publications
PLoS Genet. 5:e1000694 (2009)
Heid, I M, Huth, C, Loos, R J F, Kronenberg, F, Adamkova, V, Anand, S S, Ardlie, K, Biebermann, H, Bjerregaard, P, Boeing, H, Bouchard, C, Ciullo, M, Cooper, J A, Corella, D, Dina, C, Engert, J C, Fisher, E, Francès, F, Froguel, P, Hebebrand, J, Hegele, R A, Hinney, A, Hoehe, M R, Hu, F B, Hubacek, J A, Humphries, S E, Hunt, S C, Illig, T, Järvelin, M-R, Kaakinen, M, Kollerits, B, Krude, H, Kumar, J, Lange, L A, Langer, B, Li, S, Luchner, A, Lyon, H N, Meyre, D, Mohlke, K L, Mooser, V, Nebel, A, Nguyen, T T, Paulweber, B, Perusse, L, Qi, L, Rankinen, T, Rosskopf, D, Schreiber, S, Sengupta, S, Sorice, R, Suk, A, Thorleifsson, G, Thorsteinsdottir, U, Völzke, H, Vimaleswaran, K S, Wareham, N J, Waterworth, D, Yusuf, S, Lindgren, C, McCarthy, M I, Lange, C, Hirschhorn, J N, Laird, N & Wichmann, H-E 2009, ' Meta-analysis of the INSIG2 association with obesity including 74,345 individuals: does heterogeneity of estimates relate to study design? ', PLOS Genetics, vol. 5, no. 10, pp. e1000694 . https://doi.org/10.1371/journal.pgen.1000694
PLOS genetics 5 (2009). doi:10.1371/journal.pgen.1000694
info:cnr-pdr/source/autori:Heid I.M.; Huth C.; Loos R.J.F.; Kronenberg F.; Adamkova V.; Anand S.S.; Ardlie K.; Biebermann H.; Bjerregaard P.; Boeing H.; Bouchard C.; Ciullo M.; Cooper J.A.; Corella D.; Dina C.; Engert J.C.; Fisher E.; Frances F.; Froguel P.; Hebebrand J.; Hegele R.A.; Hinney A.; Hoehe M.R.; Hu F.B.; Hubacek J.A.; Humphries S.E.; Hunt S.C.; Illig T.; Jarvelin M.-R.; Kaakinen M.; Kollerits B.; Krude H.; Kumar J.; Lange L.A.; Langer B.; Li S.; Luchner A.; Lyon H.N.; Meyre D.; Mohlke K.L.; Mooser V.; Nebel A.; Nguyen T.T.; Paulweber B.; Perusse L.; Qi L.; Rankinen T.; Rosskopf D.; Schreiber S.; Sengupta S.; Sorice R.; Suk A.; Thorleifsson G.; Thorsteinsdottir U.; Volzke H.; Vimaleswaran K.S.; Wareham N.J.; Waterworth D.; Yusuf S.; Lindgren C.; McCarthy M.I.; Lange C.; Hirschhorn J.N.; Laird N.; Wichmann H.-E./titolo:Meta-Analysis of the INSIG2 Association with Obesity Including 74,345 Individuals: Does Heterogeneity of Estimates Relate to Study Design?/doi:10.1371%2Fjournal.pgen.1000694/rivista:PLOS genetics/anno:2009/pagina_da:/pagina_a:/intervallo_pagine:/volume:5
PLoS Genetics, Vol 5, Iss 10, p e1000694 (2009)
Robarts Vascular Research Publications
PLoS Genet. 5:e1000694 (2009)
Heid, I M, Huth, C, Loos, R J F, Kronenberg, F, Adamkova, V, Anand, S S, Ardlie, K, Biebermann, H, Bjerregaard, P, Boeing, H, Bouchard, C, Ciullo, M, Cooper, J A, Corella, D, Dina, C, Engert, J C, Fisher, E, Francès, F, Froguel, P, Hebebrand, J, Hegele, R A, Hinney, A, Hoehe, M R, Hu, F B, Hubacek, J A, Humphries, S E, Hunt, S C, Illig, T, Järvelin, M-R, Kaakinen, M, Kollerits, B, Krude, H, Kumar, J, Lange, L A, Langer, B, Li, S, Luchner, A, Lyon, H N, Meyre, D, Mohlke, K L, Mooser, V, Nebel, A, Nguyen, T T, Paulweber, B, Perusse, L, Qi, L, Rankinen, T, Rosskopf, D, Schreiber, S, Sengupta, S, Sorice, R, Suk, A, Thorleifsson, G, Thorsteinsdottir, U, Völzke, H, Vimaleswaran, K S, Wareham, N J, Waterworth, D, Yusuf, S, Lindgren, C, McCarthy, M I, Lange, C, Hirschhorn, J N, Laird, N & Wichmann, H-E 2009, ' Meta-analysis of the INSIG2 association with obesity including 74,345 individuals: does heterogeneity of estimates relate to study design? ', PLOS Genetics, vol. 5, no. 10, pp. e1000694 . https://doi.org/10.1371/journal.pgen.1000694
PLOS genetics 5 (2009). doi:10.1371/journal.pgen.1000694
info:cnr-pdr/source/autori:Heid I.M.; Huth C.; Loos R.J.F.; Kronenberg F.; Adamkova V.; Anand S.S.; Ardlie K.; Biebermann H.; Bjerregaard P.; Boeing H.; Bouchard C.; Ciullo M.; Cooper J.A.; Corella D.; Dina C.; Engert J.C.; Fisher E.; Frances F.; Froguel P.; Hebebrand J.; Hegele R.A.; Hinney A.; Hoehe M.R.; Hu F.B.; Hubacek J.A.; Humphries S.E.; Hunt S.C.; Illig T.; Jarvelin M.-R.; Kaakinen M.; Kollerits B.; Krude H.; Kumar J.; Lange L.A.; Langer B.; Li S.; Luchner A.; Lyon H.N.; Meyre D.; Mohlke K.L.; Mooser V.; Nebel A.; Nguyen T.T.; Paulweber B.; Perusse L.; Qi L.; Rankinen T.; Rosskopf D.; Schreiber S.; Sengupta S.; Sorice R.; Suk A.; Thorleifsson G.; Thorsteinsdottir U.; Volzke H.; Vimaleswaran K.S.; Wareham N.J.; Waterworth D.; Yusuf S.; Lindgren C.; McCarthy M.I.; Lange C.; Hirschhorn J.N.; Laird N.; Wichmann H.-E./titolo:Meta-Analysis of the INSIG2 Association with Obesity Including 74,345 Individuals: Does Heterogeneity of Estimates Relate to Study Design?/doi:10.1371%2Fjournal.pgen.1000694/rivista:PLOS genetics/anno:2009/pagina_da:/pagina_a:/intervallo_pagine:/volume:5
The INSIG2 rs7566605 polymorphism was identified for obesity (BMI≥30 kg/m2) in one of the first genome-wide association studies, but replications were inconsistent. We collected statistics from 34 studies (n = 74,345), including general population