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Autor:
Deqiang Zhang, J. Andrew McCammon
Publikováno v:
PLoS Computational Biology
PLoS Computational Biology, Vol 1, Iss 6, p e62 (2005)
PLoS Computational Biology, Vol 1, Iss 6, p e62 (2005)
Acetylcholinesterase (AChE) rapidly hydrolyzes acetylcholine in the neuromuscular junctions and other cholinergic synapses to terminate the neuronal signal. In physiological conditions, AChE exists as tetramers associated with the proline-rich attach