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Publikováno v:
Plastic and Reconstructive Surgery. 144:372-384
We investigated expression of prorenin receptor, angiotensin-converting enzyme, angiotensin II receptor 1, and angiotensin II receptor 2 by the embryonic stem cell-like population on the endothelium of the microvessels and perivascular cells within k
Autor:
Naoya Sakamoto, Chigusa Sato, Shunsuke Ohnishi, Kazumichi Kawakubo, Hidetaka Hosono, Naoki Murao, Akihiko Oyama, Yuhei Yamamoto, Hiroshi Furukawa, Emi Funayama
Publikováno v:
Plastic and Reconstructive Surgery. 141:390-398
Mesenchymal stem cells are a valuable cell source in regenerative medicine, and conditioned medium obtained from mesenchymal stem cells reportedly inhibits inflammation. Keloids are characterized by abnormal fibrosis, caused by fibroblasts in respons
Autor:
Eun Young Seo, Elizabeth R. Zielins, Charles Chan, Kevin J. Paik, Christopher Duldulao, Michael T. Chung, Michael T. Longaker, Stephanie Vistnes, Adrian McArdle, Ruth Tevlin, Graham G. Walmsley, David Atashroo, Derrick C. Wan, Elizabeth A. Brett
Publikováno v:
Plast Reconstr Surg
BACKGROUND: The authors have developed a novel protocol for isolating adipose-derived stem cells from human lipoaspirate. In this study, they compare their new method to a previously published standard protocol. METHODS: Human adipose-derived stem ce
Autor:
David Atashroo, Kevin C. Wang, Elizabeth R. Zielins, Andrew Spencley, Kevin J. Paik, Michael T. Longaker, Jiang Li, Derrick C. Wan, Anna Luan, Arash Momeni
Publikováno v:
Plastic and Reconstructive Surgery. 136:752-763
Adipose-derived stromal cells represent a relatively abundant source of multipotent cells, with many potential applications in regenerative medicine. The present study sought to demonstrate the use of RNA sequencing in identifying differentially expr
Autor:
Anahid Jewett, Luis A. Segovia, Patricia A. Zuk, Kameron S. Rezzadeh, Akishige Hokugo, Anna Kozlowska, Reza Jarrahy
Publikováno v:
Plastic and Reconstructive Surgery. 136:503-510
Natural killer cells are thought to represent more than 30 percent of all lymphocytes within the stromal vascular fraction of lipoaspirates. However, their physiologic interaction with adipocytes and their precursors has never been specifically exami
Adipose-Derived Stem Cells Inhibit Epidermal Melanocytes through an Interleukin-6–Mediated Mechanism
Autor:
Na Hyun Hwang, Deok Woo Kim, Eun Sang Dhong, Byung Il Lee, Eul Sik Yoon, Seung Ha Park, Min Sook Kim, Byung Joon Jeon
Publikováno v:
Plastic and Reconstructive Surgery. 134:470-480
Several investigators have postulated that human adipose-derived stem cells can be used for skin rejuvenation, but there have been few reports about their direct effects on human epidermal melanocytes. The authors studied the effects on melanocytes,
Publikováno v:
Plastic and Reconstructive Surgery. 131:174e-187e
Background The extracellular matrix is an essential microenvironment for cell survival activity. The adipose tissue extract microparticle scaffolds from human adipose tissue and small intestine submucosa microparticle scaffolds from porcine jejunum w
Autor:
Kacey G. Marra, Albert D. Donnenberg, Vera S. Donnenberg, Han Li, J. Peter Rubin, Ludovic Zimmerlin
Publikováno v:
Plastic and Reconstructive Surgery. 128:663-672
Adipose stem cells represent a heterogenous population. Understanding the functional characteristics of subpopulations will be useful in developing adipose stem cell-based therapies for regenerative medicine applications. The aim of this study was to
Publikováno v:
Plastic and Reconstructive Surgery. 126:412-425
BACKGROUND: Adipose-derived stromal cells hold promise for skeletal tissue engineering. However, various studies have observed that adipose-derived stromal cells differ significantly in their biology depending on species of derivation. In the followi