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Autor:
Anna Rita Bilia, Lorenzo Di Cesare Mannelli, Carla Ghelardini, Matteo Zanardelli, Gianluca Bartolucci, Anastasia Karioti, Alessandro Mugelli, Alfredo Vannacci
Publikováno v:
Planta Medica. 81:1045-1055
The repeated exposure to the anticancer drug oxaliplatin induces a disabling, painful neuropathy. The current pharmacological treatments are unsatisfactory and unable to modify the complex nervous damage induced by the platin derivative. Recently, we
Publikováno v:
Planta Medica. 80:1259-1268
Rhizoma Dioscoreae Nipponicae, from Discorea nipponica, is a widely used traditional Chinese herb. It is used to treat arthroncus, arthrodynia, and arthritis. Hyperuricemia is an important foundation of gouty arthritis. The current study was aimed at
Autor:
Xinlin Wu, Kuang Yu, Xin Zhou, Jianxin Wan, Jiantang Liao, Lihua Liu, Junbiao Li, Yu Zhang, Hongbo Xie
Publikováno v:
Planta Medica. 78:866-873
The purpose of this research is to investigate the effect of tanshinone IIA, an extract of the Chinese medicine Que Xie Hua Yu Tang, on uric acid nephropathy (UAN) and to elucidate the underlying mechanisms. UAN rat model was established. Fifty UAN r
Publikováno v:
Planta Medica. 76:27-33
Rhein (4,5-dihydroxyanthraquinone-2-carboxylic acid) is purified from rhubarb (Rheum officinale), a widely used traditional Chinese herb. In our previous studies, rhein was shown to be effective in ameliorating diabetic renal pathological changes and
Publikováno v:
Planta Medica. 72:14-19
A cell-based method for screening drug candidates from herbal extracts that have possible anti-type II diabetic effects was established. The differentiation of preadipocytes into adipocytes was used as a sensitive primary indicator of a drug's potent
Autor:
Jong Keun Son, Eunkyung Lee, Hye Kyung Ju, Chang Xiu Lin, Seung Ho Lee, Hyeun Wook Chang, So Hee Kim, Tae Chul Moon, Min Jung Son, Mi Jeong Kim
Publikováno v:
Planta Medica. 70:474-476
This study examined the effect of a podophyllotoxin derivative, deoxypodophyllotoxin (anthricin), which is a medicinal herb product isolated from Anthriscus sylvestris Hoffm. Deoxypodophyllotoxin was tested in a rat PCA (passive cutaneous anaphylaxis
Autor:
Hidemi Shiomoto, Keiichi Samukawa, Seiya Fukuda, Michinori Kubo, Tong Chun-ning, Hideaki Matsuda
Publikováno v:
Planta Medica. 55:18-21
The effects of a 70% methanol extract (PMe) obtained from the rhizomes of Panax japonicus C. A. Meyer on experimental thrombosis and fibrinolysis were investigated in vivo and in vitro. PMe showed a promotive effect on the activation of the fibrinoly