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Publikováno v:
Physiology & Behavior. 207:64-72
It has been reported that the degree of anxiety-like behavior differs between inbred strains of mice, and that this phenomenon was linked to the expression levels of the oxidative stress-related genes glyoxalase 1 (Glo1) and glutathione reductase 1 (
Autor:
Shigenobu Matsumura, Mayuki Odanaka, Tsutomu Sasaki, Mark Christian C. Manio, Fuka Ishikawa, Kazuo Inoue, Tohru Fushiki
Publikováno v:
Physiology & Behavior. 204:112-120
Corticosterone (CORT) is a powerful regulator of energy metabolism, and chronically high CORT levels cause obesity and diabetes in mice. It is reported that a chronically high CORT level changes food preference, increasing the intake of comfort foods
Autor:
Edith Ramírez-Rosas, P.N. Velázquez, M.C. Paredes-Carbajal, Leticia Verdugo-Díaz, Marco Antonio Juárez-Oropeza, Elia Martha Pérez-Armendáriz
Publikováno v:
Physiology & Behavior. 204:283-289
Background and aims There is a close relationship between psychosocial stress and the development of cardiovascular diseases. It has been reported that there are different alterations in endothelial function in this relationship. However, results obt
Publikováno v:
Physiology & Behavior. 202:45-51
Objectives Psychological stress has been linked to common cold symptoms. Nitric oxide (NO) is part of the first line of epithelial defense against pathogens, and beetroot juice is a source of dietary nitrate that increases NO availability. We therefo
Autor:
Kayla Rapps, Noa Hazut, Aron Weller, Gal Shoval, Raphael Mechoulam, Shira Dar, Gil Zalsman, Danielle Hen-Shoval, Liat Shbiro
Publikováno v:
Physiology & Behavior. 201:59-63
The current study explores the therapeutic potential of Cannabidiol (CBD), a compound in the Cannabis plant, using both sexes of 2 “depressive-like” genetic models, Wistar Kyoto (WKY) and Flinders Sensitive Line (FSL) rats. Rats ingested CBD (30
Autor:
Terrence Deak, Michael B. Hennessy, Jamie E. Mondello, Joshua D. Sensenbaugh, Alexis M. Garybush, Patricia A. Schiml, Darci M. Gallimore
Publikováno v:
Physiology & Behavior. 199:366-374
Disruption of attachment relations in early life is linked to greater vulnerability to depressive illness at later ages. Evidence suggests this process involves stress-induced activation of central inflammatory factors, though the specific mediators
Autor:
Kazuhiko Nakadate, Hiromi Tanaka, Kanji Yoshimoto, Ayuka Ehara, Kazutaka Shimoda, Shuich Ueda
Publikováno v:
Physiology & Behavior. 199:118-126
It is well known that an abusive environment in childhood is related to individual anxiety behavior in adulthood. Though an imbalance of adrenocorticosteroid receptors and a dysfunction of monoaminergic neuron systems have been proposed, the underlyi
Autor:
Mohammad Azab, Fadia Mayyas, Nasr Alrabadi, Saleem Ali Banihani, Karem H. Alzoubi, Omar N. Al Yacoub, Zuhair A. Hasan, Omar F. Khabour
Publikováno v:
Physiology & Behavior. 196:1-7
There is increasing evidence advocating for the causal association between oxidative stress and different neurodegenerative disorders such as Alzheimer disease and epilepsy. We have previously shown that consumption of High-fat diet (HFD) induces oxi
Publikováno v:
Physiology & Behavior. 194:474-480
Background Low-renin levels in Blacks have been associated with volume-loading hypertension (HT). Depression symptoms, frequently co-occurring with vascular dysregulation, might reflect a disturbed renin-angiotensin-aldosterone-system (RAAS). We aime
Publikováno v:
Physiology & Behavior. 194:437-449
Social isolation presents a risk factor and worsens outcome to cerebrovascular diseases; however, the underlying mechanisms remain underspecified. This study examines the effect of social environment on microglial reactivity after global cerebral isc