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Autor:
Raphaël Métivier, Françoise Lenfant, Pierre Gourdy, Coralie Fontaine, Jean-François Arnal, Pierre Chambon, Marine Adlanmerini, John A. Katzenellenbogen, Gilles Flouriot, Daniel Henrion, Benita S. Katzenellenbogen
Publikováno v:
Physiological Reviews
Physiological Reviews, American Physiological Society, 2017, 97 (3), pp.1045-1087. ⟨10.1152/physrev.00024.2016⟩
Physiological Reviews, 2017, 97 (3), pp.1045-1087. ⟨10.1152/physrev.00024.2016⟩
Physiological Reviews, American Physiological Society, 2017, 97 (3), pp.1045-1087. ⟨10.1152/physrev.00024.2016⟩
Physiological Reviews, 2017, 97 (3), pp.1045-1087. ⟨10.1152/physrev.00024.2016⟩
International audience; Estrogen receptor alpha (ERα) has been recognized now for several decades as playing a key role in reproduction and exerting functions in numerous nonreproductive tissues. In this review, we attempt to summarize the in vitro
Autor:
Lomeli R. Carpio, Andre J. Van Wijnen, Jennifer J. Westendorf, Meghan E. McGee-Lawrence, Elizabeth W. Bradley
Publikováno v:
Physiological Reviews. 95:1359-1381
Histone deacetylases (Hdacs) are conserved enzymes that remove acetyl groups from lysine side chains in histones and other proteins. Eleven of the 18 Hdacs encoded by the human and mouse genomes depend on Zn2+for enzymatic activity, while the other 7
Autor:
Ross A. D. Bathgate, Michelle L. Halls, Gabrielle E. Callander, Martina Kocan, E. T. van der Westhuizen, Roger J. Summers
Publikováno v:
Physiological Reviews. 93:405-480
There are seven relaxin family peptides that are all structurally related to insulin. Relaxin has many roles in female and male reproduction, as a neuropeptide in the central nervous system, as a vasodilator and cardiac stimulant in the cardiovascula
Publikováno v:
Physiological Reviews. 89:481-534
Nitric oxide production in response to flow-dependent shear forces applied on the surface of endothelial cells is a fundamental mechanism of regulation of vascular tone, peripheral resistance, and tissue perfusion. This implicates the concerted actio
Publikováno v:
Physiological Reviews. 87:521-544
Cardiac myocytes rapidly proliferate during fetal life but exit the cell cycle soon after birth in mammals. Although the extent to which adult cardiac myocytes are capable of cell cycle reentry is controversial and species-specific differences may ex
Autor:
Michael J. Welsh, David N. Sheppard
Publikováno v:
Physiological Reviews. 79:S23-S45
Sheppard, David N., and Michael J. Welsh. Structure and Function of the CFTR Chloride Channel. Physiol. Rev. 79 , Suppl.: S23–S45, 1999. — The cystic fibrosis transmembrane conductance regulator (CFTR) is a unique member of the ABC transporter fa
Publikováno v:
Physiological Reviews. 73:469-487
Autor:
R J Alpern
Publikováno v:
Physiological Reviews. 70:79-114
In this review I summarize a large body of work related to the mechanism of H ion secretion (and HCO 3 absorption) in the renal proximal tubule. In addition, I discuss some general mechanisms by which transporter rate is regulated in the proximal tub
Autor:
B. Swynghedauw
Publikováno v:
Physiological Reviews. 66:710-771
The goal of this review is to summarize our knowledge of the plasticity of striated muscles in terms of contractile proteins. During development or when the working conditions are changed, the intrinsic physiological properties of both cardiac and sk
Publikováno v:
Physiological Reviews. 66:855-886