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Autor:
Clemens, Eva, Broer, Linda, Langer, Thorsten, Uitterlinden, André G., de Vries, Andrica C. H., van Grotel, Martine, Pluijm, Saskia F. M., Binder, Harald, Byrne, Julianne, Broeder, Eline van Dulmen-den, Crocco, Marco, Kaiser, Melanie, Kenborg, Line, Winther, Jeanette F., Rechnitzer, Catherine, Hasle, Henrik, van der Kooi, Anne-Lotte F., Kremer, Leontien C., van der Pal, Heleen, Parfitt, Ross, Deuster, Dirk, Matulat, Peter, Spix, Claudia, Tillmanns, Amelie, Tissing, Wim J. E., Maier, Lara, am Zehnhoff-Dinnesen, Antoinette, Zolk, Oliver, Kaatsch, P., Grabow, D., Campbell, H., O’Brien, K., Kremer, L.C.M., van Dulmen-den Broeder, E., van den Berg, M.H., van den Heuvel-Eibrink, M.M., Borgmann-Staudt, A., Kuehni, C.E., Haupt, R., Kepak, T., Berger, C., Winther, J.F., Kruseova, J., Calaminus, G., Baust, K., Dirksen, U., Kuehni, Claudia E., van den Heuvel-Eibrink, Marry M.
Publikováno v:
Pharmacogenomics journal, 20(2), 294-305. Nature Publishing Group
Clemens, E, Broer, L, Langer, T, Uitterlinden, A G, de Vries, A C H, van Grotel, M, Pluijm, S F M, Binder, H, Byrne, J, Broeder, E V D, Crocco, M, Grabow, D, Kaatsch, P, Kaiser, M, Kenborg, L, Winther, J F, Rechnitzer, C, Hasle, H, Kepak, T, van der Kooi, A-L F, Kremer, L C, Kruseova, J, Kuehni, C E, van der Pal, H, Parfitt, R, Deuster, D, Matulat, P, Spix, C, Tillmanns, A, Tissing, W J E, Maier, L, Am Zehnhoff-Dinnesen, A, Zolk, O, van den Heuvel-Eibrink, M M & PanCareLIFE Consortium 2020, ' Genetic variation of cisplatin-induced ototoxicity in non-cranial-irradiated pediatric patients using a candidate gene approach : The International PanCareLIFE Study ', The Pharmacogenomics Journal, vol. 20, no. 2, pp. 294-305 . https://doi.org/10.1038/s41397-019-0113-1
Clemens, E, Broer, L, Langer, T, Uitterlinden, A G, de Vries, A C H, van Grotel, M, Pluijm, S F M, Binder, H, Broeder, E V D, Crocco, M, Kenborg, L, Winther, J F, Rechnitzer, C, Hasle, H, van der Kooi, A-L F, Kremer, L C, van der Pal, H, Parfitt, R, Deuster, D, Matulat, P, Spix, C, Tillmanns, A, Tissing, W J E, Maier, L, am Zehnhoff-Dinnesen, A, Zolk, O, van den Heuvel-Eibrink, M M, Kaatsch, P, on behalf of the PanCareLIFE consortium & van den Heuvel-Eibrink, M M 2020, ' Genetic variation of cisplatin-induced ototoxicity in non-cranial-irradiated pediatric patients using a candidate gene approach: The International PanCareLIFE Study ', Pharmacogenomics Journal, vol. 20, no. 2, pp. 294-305 . https://doi.org/10.1038/s41397-019-0113-1
Pharmacogenomics Journal, 20(2), 294-305. Nature Publishing Group
Clemens, E, Broer, L, Langer, T, Uitterlinden, A G, de Vries, A C H, van Grotel, M, Pluijm, S F M, Binder, H, Byrne, J, Broeder, E V D, Crocco, M, Grabow, D, Kaatsch, P, Kaiser, M, Kenborg, L, Winther, J F, Rechnitzer, C, Hasle, H, Kepak, T, van der Kooi, A-L F, Kremer, L C, Kruseova, J, Kuehni, C E, van der Pal, H, Parfitt, R, Deuster, D, Matulat, P, Spix, C, Tillmanns, A, Tissing, W J E, Maier, L, Am Zehnhoff-Dinnesen, A, Zolk, O, van den Heuvel-Eibrink, M M & PanCareLIFE Consortium 2020, ' Genetic variation of cisplatin-induced ototoxicity in non-cranial-irradiated pediatric patients using a candidate gene approach : The International PanCareLIFE Study ', The Pharmacogenomics Journal, vol. 20, no. 2, pp. 294-305 . https://doi.org/10.1038/s41397-019-0113-1
Clemens, E, Broer, L, Langer, T, Uitterlinden, A G, de Vries, A C H, van Grotel, M, Pluijm, S F M, Binder, H, Broeder, E V D, Crocco, M, Kenborg, L, Winther, J F, Rechnitzer, C, Hasle, H, van der Kooi, A-L F, Kremer, L C, van der Pal, H, Parfitt, R, Deuster, D, Matulat, P, Spix, C, Tillmanns, A, Tissing, W J E, Maier, L, am Zehnhoff-Dinnesen, A, Zolk, O, van den Heuvel-Eibrink, M M, Kaatsch, P, on behalf of the PanCareLIFE consortium & van den Heuvel-Eibrink, M M 2020, ' Genetic variation of cisplatin-induced ototoxicity in non-cranial-irradiated pediatric patients using a candidate gene approach: The International PanCareLIFE Study ', Pharmacogenomics Journal, vol. 20, no. 2, pp. 294-305 . https://doi.org/10.1038/s41397-019-0113-1
Pharmacogenomics Journal, 20(2), 294-305. Nature Publishing Group
Ototoxicity is a common side effect of platinum treatment and manifests as irreversible, high-frequency sensorineural hearing loss. Genetic association studies have suggested a role for SNPs in genes related to the disposition of cisplatin or deafnes