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pro vyhledávání: '"Stary ‐ Weinzinger, A"'
Autor:
Anna Stary-Weinzinger, Chonticha Suwattanasophon, Norbert Klugbauer, Lubica Lacinova, Steffen Hering, Stanislav Beyl, Maria Karmazinova
Publikováno v:
Pflügers Archiv - European Journal of Physiology. 460:1015-1028
The role of six cysteines of Ca(V)3.1 in channel gating was investigated. C241, C271, C282, C298, C313, and C323, located in the extracellular loop between segment IS5 and the pore helix, were each mutated to alanine; the resultant channels were expr
Autor:
Katrin Depil, Stanislav Beyl, Eugen Timin, Anna Stary-Weinzinger, Tobias Linder, Annette Hohaus, Steffen Hering
Publikováno v:
Pflügers Archiv - European Journal of Physiology. 464(4):391-401
Voltage sensors trigger the closed-open transitions in the pore of voltage-gated ion channels. To probe the transmission of voltage sensor signalling to the channel pore of Ca(V)1.2, we investigated how elimination of positive charges in the S4 segme