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pro vyhledávání: '"Manabu, Igarashi"'
Autor:
Xinhao Li, Kazuki Takeda, Dhoha Triki, Manabu Igarashi, Tsutomu Tanikawa, Kazuyuki D. Tanaka, Denis Fourches, Shouta M.M. Nakayama, Mayumi Ishizuka, Yoshinori Ikenaka
Publikováno v:
Pesticide biochemistry and physiology. 173:104774
Well-known 4-hydroxycoumarin derivatives, such as warfarin, act as inhibitors of the vitamin K epoxide reductase (VKOR) and are used as anticoagulants. Mutations of the VKOR enzyme can lead to resistance to those compounds. This has been a problem in