Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Roger J. Packer"'
Autor:
Mohamed S. AbdelBaki, Christopher L. Tinkle, Girish Dhall, Rebecca Ronsley, Juliette Hukin, Roger J. Packer, Sabine Mueller, Jonathan L. Finlay, Joseph Stanek, Gregory K. Friedman, Kee Kiat Yeo, Tabitha Cooney, Ashley Margol, Lindsey Hoffman, Susan N. Chi, Amar Gajjar, Christina Coleman, Stephanie Villeneuve, Karen Gauvain, Jacob G. Ellen, Michael Fisher, Richard T Graham, Andrea Cappellano, Ute Bartels, Jack Su, Mohammad H Abu-Arja, Pournima Navalkele, John T. Lucas, Nicholas G. Gottardo, Jeffrey C. Allen
Publikováno v:
Pediatr Blood Cancer
BACKGROUND: Central nervous system (CNS) germinomas are treatment-sensitive tumors with excellent survival outcomes. Current treatment strategies combine chemotherapy with radiotherapy (RT) in order to reduce the field and dose of RT. Germinomas orig
Autor:
Nicole J. Ullrich, Stewart Goldman, Jeffrey C. Allen, Mark W. Kieran, Nathan Robison, Sanjay P. Prabhu, David H. Gutmann, Michael Fisher, Bruce R. Korf, David Viskochil, Roger J. Packer, John P. Perentesis
Publikováno v:
Pediatric Blood & Cancer. 68
Data for visual acuity (VA) after treatment of neurofibromatosis type 1-associated optic pathway gliomas (NF1-OPGs) are limited. We retrospectively collected VA, converted to logMAR, before and after targeted therapy with everolimus for NF1-OPG, and
Autor:
Alexander Druy, Anastasia Ektova, Eugene I Hwang, Roger J Packer, Galina Novichkova, Alexei Maschan, Ludmila Papusha, Ludmila Yasko, Andge Valiakhmetova, Alexander Karachunsky
Publikováno v:
Pediatric Blood & Cancer. 67
Autor:
Ashley Margol, Jennifer R. Madden, Douglas Strother, Roger J. Packer, Nicholas K. Foreman, Girish Dhall, Elizabeth Wells, Amy Smith, Eric Bouffet, Lucie Lafay-Cousin, Vijay Ramaswamy, Michael D. Taylor, Mark W. Kieran, Jonathan L. Finlay, Susan N. Chi
Publikováno v:
Pediatric Blood & Cancer. 63:1527-1534
Background High-dose chemotherapy (HDC) strategies were developed to avoid unacceptable neurotoxicity associated with craniospinal irradiation in infants with embryonal brain tumors. However, the impact of molecular and pathological characterizations
Publikováno v:
Pediatric Blood & Cancer. 63:547-550
A 3-year-old boy with sickle cell anemia (SCA) presented with progressive daily emesis and was found to have an anaplastic ependymoma. Radiation therapy and chemotherapy are usually employed after subtotal resections of anaplastic ependymomas, althou
Autor:
Peter C. Burger, Ian F. Pollack, Regina I. Jakacki, Roger J. Packer, Joel W. Goldwein, Minesh P. Mehta, Nancy J. Tarbell, James M. Boyett, Mehmet Kocak
Publikováno v:
Pediatric Blood & Cancer. 62:776-783
Background Supratentorial PNETs (sPNET) are uncommon embryonal malignancies of the central nervous system whose prognosis has historically been poor. We evaluated the outcome and prognostic factors of children with sPNET treated prospectively on a Ch
Autor:
Nicholas J. Patronas, Dusica Babovic-Vuksanovic, Seth M. Steinberg, Eva Dombi, Mark W. Kieran, Anne Goodwin, Wendy Goodspeed, Staci Martin, Frank M. Balis, Brigitte C. Widemann, Allison A. King, Elizabeth Fox, Stewart Goldman, Roger J. Packer, Susan M. Blaney, Jeffrey Solomon, Bruce M. Cohen, Pamela L. Wolters
Publikováno v:
Pediatric Blood & Cancer. 61:1598-1602
Background Pirfenidone, an oral anti-inflammatory, antifibrotic agent with activity in idiopathic pulmonary fibrosis, may mediate anti-tumor activity in neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN) by inhibition of fibroblast proli
Autor:
Bruce R. Korf, Brigitte C. Widemann, David H. Gutmann, Alexander A. Vinks, Brian Weiss, Elizabeth K. Schorry, Roger J. Packer, John P. Perentesis, Pamela L. Wolters, Michael Fisher, Eva Dombi, Alan B. Cantor
Publikováno v:
Pediatric Blood & Cancer. 61:982-986
Background Patients with Neurofibromatosis Type 1 (NF1) have an increased risk of developing tumors of the central and peripheral nervous system, including plexiform neurofibromas (PN), which are benign nerve sheath tumors that are among the most deb
Autor:
Patrick Y. Wen, Michael D. Prados, Katherine E. Warren, Tina Young Poussaint, Stefan Rutkowski, Gilbert Vezina, Ian F. Pollack, Darren Hargrave, Mark W. Kieran, Roger J. Packer, Larry E. Kun, Stewart Goldman, David Zurakowski
Publikováno v:
Pediatric Blood & Cancer. 60:1397-1401
Criteria for new drug approval include demonstration of efficacy. In neuro-oncology, this is determined radiographically utilizing tumor measurements on MRI scans. Limitations of this method have been identified where drug activity is not reflected i
Autor:
Tianni Zhou, Amar Gajjar, F. Daniel Armstrong, Dana Wallace, Karin S. Walsh, Emi Holmes, M. Douglas Ris, Roger J. Packer
Publikováno v:
Pediatric Blood & Cancer. 60:1350-1357
cerebral vasculature, disruption of the blood–brain barrier, and direct damage to cerebral white matter as well as damage to neural progenitor cells in neuronal niches [6,7] Purpose. Assess the intellectual and academic outcomes as well as risk fac