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Autor:
Ming Qi, Xiuyan Wang
Publikováno v:
Pathology - Research and Practice. 214:1787-1793
Background MicroRNAs bind the 3′ untranslated regions (3′-UTRs) of mRNAs and thereby regulate gene expression post-transcriptionally and play an important role in cancer delvelopment. In the present study, we have explored the role of miR-718 in
Autor:
Fei Pei, Xinying Liu, Rui Wu, Beiying Liu, Jiang-feng You, Xiaodan Liu, Xiaoqiang Wang, Qichen Liu, Ran Tang, Yakun Shao, Kuangen Zhang
Publikováno v:
Pathology - Research and Practice. 214:1904-1908
Endometrial dedifferentiated carcinoma is a rare, malignant tumor whose molecular alterations have not been clarified yet. We report a novel case of a 61-year old woman who presented with irregular vaginal bleeding after menopause and a 3 cm uterus m
Autor:
Gulgun Erdogan, Elif Pestereli, Mualla Ozcan, Hülya Ayık Aydın, Tayup Simsek, Zeynep Bayramoğlu
Publikováno v:
Pathology - Research and Practice. 214:1868-1872
Objective ROS1 is an orphan receptor protein tyrosine kinase which is supposed to undergo genetic rearrangement in carcinogenesis. In the current study, we aimed to investigate the frequency and clinicopathologic features associated with ROS1 gene fu
Publikováno v:
Pathology - Research and Practice. 214:1556-1563
Transporter associated with antigen processing protein (TAP) is a heterodimer protein consist of TAP1 and TAP2, act a pivotal part in the immune surveillance. In recent days, controversial relationships were reported between TAP polymorphisms and can
Autor:
Naoki Wada, Keisuke Kawasaki, Kenji Ohshima, Satoshi Nojima, Eiichi Morii, Shinya Kusumoto, Masako Kurashige, Shinichiro Tahara, Mitsuyo Tone, Jun-ichiro Ikeda
Publikováno v:
Pathology - Research and Practice. 214:1667-1674
Glutamine (Gln) is important not only for cell proliferation but also for differentiation. Although Gln is essential for plasmacytic differentiation of lymphocytes, no study has been done on the effect of Gln on differentiation of tumor cells, such a
Publikováno v:
Pathology - Research and Practice. 214:1726-1731
Endometrial stromal sarcomas are rare tumors that may recur or metastasize many years after their initial presentation. Though most recurrences are within the pelvis, distant metastases can occur, and are most common to the lungs. Metastases to the l
Publikováno v:
Pathology - Research and Practice. 214:1517-1523
Objectives A vast of transcripts have been found aberrantly expressed in cancers functioning as mechanical factors. The association between the deregulation of long noncoding RNAs (lncRNAs) and clinicopathologic features is one of the most investigat
Publikováno v:
Pathology - Research and Practice. 214:1732-1737
Squamous cell carcinoma with pseudoangiosarcomatous features is a rare but well-recognized variant of squamous cell carcinoma. These tumors exhibit complex anastomosing channels lined by neoplastic cells, histologically mimicking a vasoformative mese
Publikováno v:
Pathology - Research and Practice. 214:1648-1654
NIMA Related Kinase 6 (Nek6) is a protein kinase involved in various cellular processes, including cell cycle regulation, apopotosis, senescence, telomere maintainance and chemoresistance. In the present study, we investigated the role of Nek6 in bre
Publikováno v:
Pathology - Research and Practice. 214:1655-1660
This study was aimed to explore the potential roles of miR-130b for the efficacy of radiofrequency ablation (RFA) in patients with primary hepatocellular carcinoma (PHC).The serum sample of 110 PHC patients, which underwent RFA treatment, was collect