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Publikováno v:
Pathology - Research and Practice. 215:910-917
Human epidermal growth factor 2 (HER2) is a candidate therapeutic and prognostic marker for rectal cancer treated with neoadjuvant chemoradiotherapy. The specific frequency and prognostic role of HER2 protein expression and HER2 gene amplification in
Autor:
Yanjie Shuai, Li Ma
Publikováno v:
Pathology - Research and Practice. 215:29-33
Neoadjuvant chemotherapy(NCT) has become the standard treatment for breast cancer. The information about the tumor's sensitivity to chemotherapy and prognostic significance based on response to therapy can be provided after individualized neoadjuvant
Publikováno v:
Pathology - Research and Practice. 214:1253-1259
Previous studies demonstrated that AIB1 or HER2 copy number gain (CNG), respectively, were independent predictors for poor prognosis of glioma patients, especially in females. We hypothesize that there are some connections between the two genes and s
Publikováno v:
Pathology - Research and Practice. 229:153693
Background Small cell lung cancer (SCLC) is a malignant lung neuroendocrine tumor with early metastasis, rapid progression, and poor outcomes. Insulinoma-associated protein 1 (INSM1) has been an excellent marker for neuroendocrine (NE) differentiatio
Autor:
Yawei Zhang, Kuaile Zhao, Xiaolong Fu, Weiwei Yu, Xi Yang, Qiao Wei, Haiquan Chen, Congying Xie, Zhengfei Zhu, Weixin Zhao, Li Chu, Hecheng Li, Jiaqing Xiang, Menghong Sun
Publikováno v:
Pathology - Research and Practice. 214:1017-1023
The human epidermal growth factor receptor (EGFR) family has been widely studied in cancer, however, the prognostic role of EGFR family expression in lymph node-negative esophageal squamous cell carcinoma (ESCC) patients have not been invalidated. Th
Autor:
Bingjian Lu, Lanlan Tang
Publikováno v:
Pathology - Research and Practice. 214:871-875
The object of this study is to investigate the prognosis and potential histologic origin of uterine intravenous leiomyomatosis (IVL). We retrospectively analyzed the clinicopathologic and immunohistochemical features of 13 cases of IVL from a single
Autor:
Seung Duk Lee, Eun-Kyung Hong, Sang-Jae Park, Jungnam Joo, Hyerim Byeon, Sung-Sik Han, Seong Hoon Kim, Bohyun Kim, YunSung Seo, Dong-Eun Lee
Publikováno v:
Pathology - Research and Practice. 214:814-820
Background New biomarkers are essential for improving the prediction of the survival and prognosis of patients with hepatocellular carcinoma (HCC). Alpha-fetoprotein (AFP) is the most widely used biomarker, but the low sensitivity and specificity lim
Autor:
Stratigoula Sakellariou, Ilenia Chatziandreou, Georgios E. Theodoropoulos, Penelope Korkolopoulou, Efstratios Patsouris, Nikolaos V. Michalopoulos, Angelica A. Saetta, Spyridon Tsikalakis
Publikováno v:
Pathology - Research and Practice. 214:826-834
TNF-related, apoptosis-inducing ligand (TRAIL) apoptotic pathway constitutes a promising therapeutic target due to high selectivity and low toxicity of TRAIL targeting agents when administered in combination therapies. 106 colorectal cancers were exa
Publikováno v:
Pathology - Research and Practice. 214:848-856
Neuroendocrine differentiation (NED) is a common phenomenon in prostate cancer, and it has been associated with poor prognosis in some studies of primary prostate cancer. Incidence and patterns of NED in metastatic prostate cancer sites have not been
Autor:
Jeong-Yoon Song, Kyu Yeoun Won, Anbok Lee, Sung-Jig Lim, Sun Young Cho, SaeGwang Park, Sang-Ah Han
Publikováno v:
Pathology - Research and Practice. 214:619-624
Many studies have reported that Aldehyde dehydrogenase 1 (ALDH1) and tumor-infiltrating lymphocytes (TIL) are related to breast cancer prognosis. However, the clinical significance of ALDH1 and tumor-infiltrating immune cells in breast cancer has not