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Publikováno v:
Pathology - Research and Practice. 215:977-982
Introduction Syndecan-1 is heparan sulfate proteoglycans (HSPGs) that is used as coreceptors for signaling of growth factors. The comprehensive effect of syndecan-1 is to augment receptor stimulation at little ligand concentrations. The goal of this
Publikováno v:
Pathology - Research and Practice. 215:880-884
Papillary thyroid carcinoma (PTC) is the most common differentiated thyroid cancer in children; and the follicular variant is the second most common variant after the classic subtype. The histological appearance of follicular variant of papillary thy
Publikováno v:
Pathology - Research and Practice. 215:1012-1019
Colorectal cancer (CRC) is the third most common malignancy and a leading cause of cancer-related death worldwide. GEF-H1 is considered a RhoA-specific guanine nucleotide exchange factor. GEF-H1 upregulation may contribute to cancer cell migration an
Publikováno v:
Pathology - Research and Practice. 215:1020-1032
Background Although previous researchers have analyzed the expression level of vimentin in nasopharyngeal carcinoma (NPC), the sample size of each study was too small, and there was no further in-depth study utilizing microarray and RNA-sequencing da
Publikováno v:
Pathology - Research and Practice. 215:676-682
Background The miR-129-5p has been reported to be aberrant expression and exert vital roles in tumor progression of various malignancies. However, the effects on EMT in gastric cancer and its precise molecular mechanism in gastric cancer remain uncle
Publikováno v:
Pathology - Research and Practice. 215:519-524
Signal transducer and activator of transcription 5 (STAT5) plays a key role in the malignancy of many tumors and has been identified as a therapeutic target. However, the role of STAT5A in osteosarcoma is still unclear.98 osteosarcoma patients were o
Publikováno v:
Pathology - Research and Practice. 215:571-579
Background Long non-coding RNAs (lncRNAs) have been reported in human cancers as regulators for biological processes. LncRNA bladder cancer associated transcript 1 (BLACAT1) has been found to exert oncogenic function in cervical cancer and lung cance
Publikováno v:
Pathology - Research and Practice. 215:532-538
Lysine-specific histone demethylase 1A gene (KDM1A) promotes tumorigenesis. The aim of this study was to investigate the association between KDM1A methylation and colorectal cancer (CRC). Currently, we collected 37 paired CRC tissues and adjacent non
Autor:
Feng Zhang, Fenglai Yuan, Zong-Ning Miao, Xuetao Li, Aihua Zhu, Haibin Wu, Youxin Zhou, Bei Wang
Publikováno v:
Pathology - Research and Practice. 215:600-606
Gliomas are the most common primary brain malignant tumors in humans. Glioblastoma multiforme(GBM) is the most malignant intracranial tumor with a relatively poor prognosis. There promote us to find effective anti-cancer therapies to reduce cancer mo
Autor:
Sug Hyung Lee, Yun Sol Jo, Su Yeon Yeon, Yeun-Jun Chung, Min Sung Kim, Seung-Hyun Jung, Eun Ji Choi
Publikováno v:
Pathology - Research and Practice. 215:209-214
β2-microglobulin (B2M), a component of major histocompatibility complex class I, plays an important role in host immune reaction to tumor, and inactivation of B2M is known to contribute to resistance to immune checkpoint blockade (ICB) treatment. To