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Publikováno v:
Pathology - Research and Practice. 231:153779
CIC-DUX4 fusion gene associated sarcoma is a new emerging subgroup of round cell sarcoma with Ewing sarcoma-like morphology. Distinguishing these tumors from Ewing sarcoma family tumors (ESFT) is critical because of the clinical impact but is still c
Publikováno v:
Pathology - Research and Practice. 214:343-349
Type B3 thymoma and thymic squamous cell carcinoma (SqCC) often cause a diagnostic problem due to their histological similarities. The aim of this study is to identify EZH2 as a novel and powerful biomarker that can effectively distinguish thymic SqC
Publikováno v:
Pathology - Research and Practice. 214:431-435
Background Low-grade malignant endolymphatic sac tumor (ELST) is a rare neoplasm, occurring in the inner ear and invading the temporal bone. This study aims to investigate the clinicopathological features of low-grade malignant ELSTs. Methods The cli
Autor:
Yoshinao Oda, Shin Ishihara, Yuichi Yamada, Masato Yoshimoto, Yasuharu Nakashima, Kenichi Kohashi, Yu Toda, Hiroshi Otsuka, Hidetaka Yamamoto
Publikováno v:
Pathology - Research and Practice. 214:417-425
The histological definitive diagnosis of malignant peripheral nerve sheath tumor (MPNST) is quite difficult because the morphological features are not specific and no useful immunohistochemical marker has been identified. Loss-of-function mutations i
Autor:
Juan Pablo García de la Torre, María Bengoa Caamaño, Rosa Noguera, Mª Luisa García Mauriño, Lara Navarro, Susana Martín-Vañó, Veronica Andrade-Gamarra, Clara Alfaro-Cervello, Samuel Navarro, Gema Nieto
Publikováno v:
Pathology - Research and Practice. 213:1435-1439
Small round cell sarcomas are aggressive bone and soft tissue tumors that predominantly affect children and young adults. A new group of sarcomas with a recurrent BCOR-CCNB3 gene fusion has been recently identified in previously unclassifiable small
Publikováno v:
Pathology - Research and Practice. 213:1306-1309
Epstein-Barr Virus-associated smooth muscle tumor (EBV-SMT) is a rare mesenchymal tumor typically seen in immunocompromised patients. Here, we report a case of EBV-SMT and associated granulomatous inflammation in the liver of a 32-year-old man with h
Publikováno v:
Pathology - Research and Practice. 213:1237-1241
Background In diabetic patients, subcutaneous insulin injection may cause several types of injection site-related lesions, such as lipoatrophy, insulin-induced cutaneous lipohypertrophy (IICL), allergic reaction, and iatrogenic localized insulin-deri
Autor:
Karina Munhoz de Paula Alves Coelho, Paulo Henrique Condeixa de França, Hercílio Fronza Júnior, Jaqueline Stall, Rodrigo Blasius
Publikováno v:
Pathology - Research and Practice. 213:1067-1071
Aim Malignant melanoma is an aggressive disease and its incidence is increasing worldwide. Genetic predisposition and exposure to environmental factors, especially sunlight, are risk factors. Histopathologic distinction between nevi and melanomas can
Autor:
Weiping Liu, Min Chen, Fen Li, Sha Zhao, Gan-Di Li, Wenyan Zhang, Limin Gao, Xiang-Lan Zhu, Xiu-Hui Zhang, Xiao-yu Liu
Publikováno v:
Pathology - Research and Practice. 213:598-605
Background It is a great challenge for pathologists to initially diagnose metastatic malignant mesothelioma (MM) by the lymph node biopsy without any history of primary MM. Because the onset of MM is hidden and the metastatic MM in lymph node is rela
Claudin 6 expression is useful to distinguish myxofibrosarcomas from other myxoid soft tissue tumors
Autor:
Katsumi Harimaya, Hiroshi Otsuka, Yuichi Yamada, Kenichi Kohashi, Yoshinao Oda, Katsumi Takizawa, Hidetaka Yamamoto, Takeshi Iwasaki, Yukihide Iwamoto, Hirofumi Bekki
Publikováno v:
Pathology - Research and Practice. 213:674-679
Myxofibrosarcoma (MFS) is characterized by abundant myxoid stroma, a wide spectrum of cytological atypia, and frequent local recurrence. Some soft tissue tumors with myxoid stroma can histologically mimic MFS, but have different biological behaviors.