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Autor:
Xinming Chen, Bo Zhang, Fuwei Qi, Fei Ju, Qiong Wu, Qiuhong Wang, Ziheng Wang, Chenlin Zhang, You Lang Zhou, Shiqi Ren, Qianqian Ma, Yidan Sun, Qun Xue, Xinyi Hu, Ran Xu
Publikováno v:
Pathology - Research and Practice. 215:1038-1048
Background and objective The underlying molecular mechanisms of gastric cancer (GC) have yet not been investigated clearly. In this study, we aimed to identify hub genes involved in the pathogenesis and prognosis of GC. Methods We integrated five mic
Publikováno v:
Pathology - Research and Practice. 215:880-884
Papillary thyroid carcinoma (PTC) is the most common differentiated thyroid cancer in children; and the follicular variant is the second most common variant after the classic subtype. The histological appearance of follicular variant of papillary thy
Publikováno v:
Pathology - Research and Practice. 215:910-917
Human epidermal growth factor 2 (HER2) is a candidate therapeutic and prognostic marker for rectal cancer treated with neoadjuvant chemoradiotherapy. The specific frequency and prognostic role of HER2 protein expression and HER2 gene amplification in
Publikováno v:
Pathology - Research and Practice. 215:1033-1037
Purpose To screen novel candidate biomarkers in primary colorectal cancer (CRC), and indentify their clinical valuation in progress of colorectal cancer. Methods By using antibody microarray, 274 target proteins in tissue samples from primary colorec
Publikováno v:
Pathology - Research and Practice. 215:1066-1070
In the era of personalized medicine, lung cancer is a typical disease which can be treated strategically based on the patient's histological and molecular diagnosis. Immunohistochemistry (IHC), fluorescence in-situ hybridization (FISH), Sanger sequen
Publikováno v:
Pathology - Research and Practice. 215:918-923
Polycystic ovary syndrome (PCOS) is one of the most complex and common reproductive and endocrinologic disorders in the child-bearing age of women. Recently, miR-222 were reported to be associated with the etiology of PCOS. However, the function of m
Autor:
Gu Xiuli, Meiqin Wang, Fukang Yaolong, Yuxiao Liu, Xianhong Feng, Bifeng Chen, Tiansong Li, Yuwei Jiao
Publikováno v:
Pathology - Research and Practice. 215:1061-1065
The rs3787016 polymorphism, in polymerase II polypeptide E (POLR2E), was previously identified as being associated with the risk for prostate cancer, esophageal cancer, breast cancer, papillary thyroid carcinoma and liver cancer, suggesting that rs37
Publikováno v:
Pathology - Research and Practice. 215:988-994
Objective Recent studies have shown that Chondroitin polymerizing factor (CHPF) is abnormally expressed in malignant tumors, however, the expression of CHPF in lung adenocarcinoma (LUAD) has not been reported. In this study, the relationship of CHPF
Publikováno v:
Pathology - Research and Practice. 215:1012-1019
Colorectal cancer (CRC) is the third most common malignancy and a leading cause of cancer-related death worldwide. GEF-H1 is considered a RhoA-specific guanine nucleotide exchange factor. GEF-H1 upregulation may contribute to cancer cell migration an
Publikováno v:
Pathology - Research and Practice. 215:924-930
Oral squamous cell carcinoma (OSCC) is a common type of malignant oral cancer with high recurrence. MYC-induced long non-coding RNA (MINCR) has been reported as a tumor suppressor in liver cancer and lung cancer. Whereas, it is unknown whether MINCR