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Publikováno v:
Pathology - Research and Practice. 215:519-524
Signal transducer and activator of transcription 5 (STAT5) plays a key role in the malignancy of many tumors and has been identified as a therapeutic target. However, the role of STAT5A in osteosarcoma is still unclear.98 osteosarcoma patients were o
Publikováno v:
Pathology - Research and Practice. 215:265-271
Although dose intensification strategies achieve a favorable prognosis for pediatric patients of T-lmphoblastic lymphoma/leukemia (T-LBL/ALL), numerous side effects have been followed. Molecular targeted therapies will be needed to optimize the curr
Autor:
I. Papadimitriou-Olivgeri, Nicholas A. Athanasou, Yasuhito Tanaka, D. Herrero-Charrington, Y. Uchihara, E. Iwata
Publikováno v:
Pathology - Research and Practice. 214:1661-1666
Localised (transthyretin-associated) amyloid is commonly seen in articular/periarticular tissues of elderly individuals. Whether age-associated, amyloid deposition occurs in foot and ankle (FA) tissues has not previously been investigated. In this st
Publikováno v:
Pathology - Research and Practice. 214:1726-1731
Endometrial stromal sarcomas are rare tumors that may recur or metastasize many years after their initial presentation. Though most recurrences are within the pelvis, distant metastases can occur, and are most common to the lungs. Metastases to the l
Autor:
Hans Bösmüller, Bence Sipos, Vanessa Pfefferle, Falko Fend, Zeid Bittar, Marius Horger, Veit Scheble
Publikováno v:
Pathology - Research and Practice. 214:1136-1141
Microvessel density is an indicator of tumor-driven neoangiogenesis. Hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (ICC) have distinct vascular patterns, which are also reflected in their imaging characteristics. Since a signific
Publikováno v:
Pathology - Research and Practice. 214:974-977
Previous studies have shown a correlation between the expression of H3K27me3 and pathological characteristics of malignant tumors. This study aimed to investigate the association of H3K27me3 and VEGF expression with clinical outcomes of synovial sarc
Publikováno v:
Pathology - Research and Practice. 214:881-888
IDH mutation and MGMT promoter methylation are reliable prognostic and predictive biomarkers in grade II–IV diffuse gliomas. Recurrent mutations in the promoter region of the telomerase reverse transcriptase (TERTp) gene have also been found in dif
Autor:
Eduardo Rodrigues Fregnani, Gleyson Kleber do Amaral-Silva, Rosana Lima Pagano, Oslei Paes de Almeida, Bernar Monteiro Benites, Marco Aurélio Petroni Montezuma, Felipe Paiva Fonseca, Fernando Augusto Soares, Ciro Dantas Soares
Publikováno v:
Pathology - Research and Practice. 214:907-913
Ameloblastoma is a locally aggressive neoplasm with a poorly understood pathogenesis. Therefore, the aim of this study is to investigate whether COX-2 expression is associated with ameloblastoma microvascular density (MVD) and with tumor aggressivene
Autor:
Mehar Chand Sharma, Rajeev Sharma, Pankaj Pathak, Sujata Chaturvedi, Arvind Ahuja, Minakshi Bhardwaj, Chitra Sarkar, Vaishali Suri, Gaurav Khanna, Ajay Garg
Publikováno v:
Pathology - Research and Practice. 214:679-685
Epithelioid glioblastoma (e-gbm) is a recently described variant of glioblastoma (GBM) which is associated with short survival and now added as a provisional entity to WHO 2016 classification of CNStumors. About half of these tumors show characterist
Autor:
Masanobu Sato, Ryuji Yasumatsu, Rina Jiromaru, Takashi Nakagawa, Yui Hatanaka, Muneyuki Masuda, Toshimitsu Nishijima, Kenichi Taguchi, Yoshinao Oda, Hidetaka Yamamoto
Publikováno v:
Pathology - Research and Practice. 214:586-592
Differential diagnosis among basal cell adenoma (BCA), basal cell adenocarcinoma (BCAC), adenoid cystic carcinoma (ACC) and pleomorphic adenoma (PA) of the salivary gland can be challenging due to their similar histological appearance. Although frequ