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Publikováno v:
Pathology - Research and Practice. 215:1012-1019
Colorectal cancer (CRC) is the third most common malignancy and a leading cause of cancer-related death worldwide. GEF-H1 is considered a RhoA-specific guanine nucleotide exchange factor. GEF-H1 upregulation may contribute to cancer cell migration an
Publikováno v:
Pathology - Research and Practice. 215:924-930
Oral squamous cell carcinoma (OSCC) is a common type of malignant oral cancer with high recurrence. MYC-induced long non-coding RNA (MINCR) has been reported as a tumor suppressor in liver cancer and lung cancer. Whereas, it is unknown whether MINCR
Publikováno v:
Pathology - Research and Practice. 215:632-638
Background Previous studies have indicated that Trichosanthin (TCS) exerts anti-virus, immunoregulation and a broad spectrum anti-tumor pharmacological activities. Trichosanthin is a promising agent for the treatment of cervical cancer. However, the
Autor:
Li Li, Weidong Zhao
Publikováno v:
Pathology - Research and Practice. 215:439-445
Long non-coding RNAs (LncRNAs) are acknowledged as crucial regulators in tumorigenesis and tumor progression. In this study, we explored the mechanism and function of lncRNA HCP5 in osteosarcoma (OS). At first, five lncRNAs were chosen from GeneCard
Publikováno v:
Pathology - Research and Practice. 215:571-579
Background Long non-coding RNAs (lncRNAs) have been reported in human cancers as regulators for biological processes. LncRNA bladder cancer associated transcript 1 (BLACAT1) has been found to exert oncogenic function in cervical cancer and lung cance
Publikováno v:
Pathology - Research and Practice. 215:499-505
Profilin 1 (PFN1) is a critical actin-regulatory protein; however, its functional role in hepatocellular carcinoma (HCC) progression remains to be further elucidated. In the present study, we observed that the expression levels of PFN1 were significa
Autor:
Bo Ge, Chuang Wang, Zhipeng Xu, Xuebao Xiang, Tianyu Zhang, Yi Chen, Ya Peng, Jiefu Huang, Hailin Shi, Li Gao
Publikováno v:
Pathology - Research and Practice. 215:302-307
It is identified that long non-coding RNAs (lncRNAs) play important roles in tumorigenesis. LncRNA SNHG7 has been found to be an oncogene in varieties of tumors including bladder cancer. However, its potential regulatory mechanism in bladder cancer s
Autor:
Jingjing Tian, Zhihui Dong, Xianping Li, Min Wang, Kan Zhang, Aiguo Tang, Huan Song, Fang Chen, Yixin Xie, Xiaomeng Xia, Min Yang
Publikováno v:
Pathology - Research and Practice. 215:315-321
To construct a lentiviral vector with endostatin (ES) and staphylococcal enterotoxin CBy inserting ES and SEC3 gene into the plasmid and then transfect 293 T cell, the co-expressed (SEC3-ES) vector were constructed. A series of experiments in vitro w
Publikováno v:
Pathology - Research and Practice. 215:329-334
Wilms'tumor is the most common malignant tumor with a poor clinical prognosis because of metastasis or recurrence among children worldwide. CD151, a member of transmembrane 4 superfamily, has now been confirmed to be involved in tumor progression inc
Autor:
Lorenzo Alibardi
Publikováno v:
Pathology - Research and Practice. 215:215-221
The ultrastructural immunolocalization of telomerase and hyaluronate has been studied in a case of oropharyngeal squamous carcinoma. Immunofluorescence shows that telomerase immunolabeling is present in the cytoplasm and in nuclei of some keratinocyt