Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Wei Wang"'
Publikováno v:
Organic Letters. 23:7656-7660
Herein we report a cascade cocatalysis strategy for the facile construction of chiral γ,γ-disubstituted butenolides. The synthetic manifold employs simple alkynoic acids instead of the preformed silyloxy furans or 5-substituted furan-2(3H)-ones. In
Autor:
Yu-Han Qiao, Yi Lu, Jia-Xue Wu, Yong-Fei Li, Jianmin Dou, Dacheng Li, Huai-Wei Wang, Qing-Xia Yao
Publikováno v:
Organic Letters. 23:7177-7182
Herein, we disclose a RhIII-catalyzed heteroarylation of C(sp3)-H and C(sp2)-H bonds in heterocycles with organoboron reagents. This protocol displays high efficiency and excellent functional group tolerance. A range of heterocyclic boronates with st
Publikováno v:
Organic Letters. 23:6589-6593
A nickel-catalyzed one-pot carbonylation reaction of 2-bromobenzenesulfonyl chlorides with alkynes for the synthesis of thiochromenones has been established. Both terminal and internal alkynes were suitable substrates in this carbonylative transforma
Publikováno v:
Organic Letters. 23:3064-3069
An efficient protocol for the construction of functionalized 3-alkenyl benzofurans is demonstrated under metal-free conditions using catalytic amount of phosphine proceeding an intramolecular Wittig reaction. This one-pot reaction initiated by the ph
Publikováno v:
Organic Letters. 23:1406-1410
An expedient synthesis of β-silyl α-amino acids is reported via the application of visible-light-mediated hydrosilylation. The reaction utilizes readily accessible and structurally diverse hydrosilanes to provide radicals for conjugate addition to
Autor:
Jia-Xue Wu, Yi Lu, Meng-Xin Tian, Jianmin Dou, Huai-Wei Wang, Yu-Han Qiao, Yong-Fei Li, Qing-Xia Yao, Dacheng Li, Qiu-Ping Wang
Publikováno v:
Organic Letters. 23:656-662
RhIII-catalyzed sp2 C-H cross-coupling of acrylamides with organoboron reactants has been accomplished using a commercially available N-2,6-difluoroaryl acrylamide auxiliary. A broad range of aryl and vinyl boronates as well as a variety of heterocyc
Autor:
Jinjiang Zhu, Stephanie Scales, Michael R. Collins, Joyann S. Barber, Michelle Tran-Dubé, Fen Wang, Alexander Burtea, Wei Wang, Jillian E. Spangler, Ryan L. Patman, T Patrick Montgomery, Graham Smith, Shouliang Yang
Publikováno v:
Organic letters. 22(22)
Indazoles represent a privileged motif in drug discovery. However, the formation of highly substituted indazoles can require the execution of lengthy synthetic routes with minimal opportunities to introduce diversity. In this report, we disclose the
Publikováno v:
Organic letters. 22(15)
An unprecedented organocatalytic enantioselective [4 + 2] cycloaddition reaction of vinyl quinolines with dienals is achieved with the synergistic activation of CH3SO3H and a chiral aminocatalyst. The power of the process is demonstrated by its high
Publikováno v:
Org Lett
A mild, versatile organophotoredox protocol has been developed for the preparation of diverse, enantioenriched α-deuterated α-amino acids. Distinct from the well-established two-electron transformations, this radical-based strategy offers the unriv
Publikováno v:
Organic letters. 22(1)
An unprecedented method that enables the direct transformation of unprotected secondary aliphatic amines into functionalized N-heterocycles in the absence of transition metals was developed. The activation of these NH-free amines by the iodonium ylid