Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Dean W. Felsher"'
Autor:
Candace J. Poole, Honglin Li, Atul Lodh, Wenli Zheng, Aleksey Yevtodiyenko, Daniel F. Liefwalker, Jan van Riggelen, Dean W. Felsher
Publikováno v:
Oncotarget
// Candace J. Poole 1, * , Wenli Zheng 1, * , Atul Lodh 1 , Aleksey Yevtodiyenko 2 , Daniel Liefwalker 2 , Honglin Li 1 , Dean W. Felsher 2 and Jan van Riggelen 1 1 Augusta University, Department of Biochemistry and Molecular Biology, Augusta, GA 309
Publikováno v:
Oncotarget
Oncogene inactivation in both clinical targeted therapies and conditional transgenic mouse cancer models can induce significant tumor regression associated with the robust induction of apoptosis. Here we report that in MYC-, RAS-, and BCR-ABL-induced
Autor:
Alper Yetil, Arvin M. Gouw, Benedict Anchang, Ramya Parameswaran, Stacey J. Adam, Dean W. Felsher, Sylvia K. Plevritis, Jan van Riggelen, Tahera Zabuawala
Publikováno v:
Oncotarget
MYC-induced T-ALL exhibit oncogene addiction. Addiction to MYC is a consequence of both cell-autonomous mechanisms, such as proliferative arrest, cellular senescence, and apoptosis, as well as non-cell autonomous mechanisms, such as shutdown of angio
Autor:
Vivek Kaimal, Ian Lai, Meital Gabay-Ryan, Dean W. Felsher, Adriane Mosley, Virginie Baylot, Priya Karmali, Xinqiang Huang, Renumathy Dhanasekaran, Sonya Zabludoff, Jian Li
Publikováno v:
Oncotarget
Hepatocellular carcinoma (HCC) remains a significant clinical challenge with few therapeutic options. Genomic amplification and/or overexpression of the MYC oncogene is a common molecular event in HCC, thus making it an attractive target for drug the
Publikováno v:
Oncotarget. 7(21)
All highly proliferating cells have two absolute requirements: abundant sources of energy and building blocks such as proteins, carbohydrates, and lipids. Specific gene products that coordinate massive induction of both energy and these chemical prod
Publikováno v:
Oncotarget. 5:7986-7987
The term “oncogene addiction” was first coined by Dr. Bernard Weinstein to describe the exquisite dependency of tumor cells on the expression of specific oncogenes for their relentless proliferation and survival [1]. Since cancers generally have
Publikováno v:
Oncotarget
Brian A. DeChristopher 1,* , Alice C. Fan 2,* , Dean W. Felsher 2 , Paul A. Wender 1 1 Departments of Chemistry and Chemical and Systems Biology, Stanford University, Stanford, CA 94305-5080 2 Division of Oncology, Stanford University School of Medic